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Biology and Biochemistry

D-Index
52
Citations
12998
World Ranking
16517
National Ranking
6839

Overview

Jakob Reiser is affiliated with the Center for Biologics Evaluation and Research in the United States. Their research primarily focuses on areas within biochemistry, genetics, and molecular biology, with significant contributions in medicine. They have produced work notably in molecular biology, genetics, oncology, cardiology and cardiovascular medicine, and epidemiology.

The main research topics addressed by Reiser include:

  • Virus-based gene therapy research
  • Viral infectious diseases and gene expression in insects
  • CRISPR and genetic engineering
  • CAR-T cell therapy research
  • Viral infections and immunology research
  • Virology and viral diseases
  • Transgenic plants and applications

Reiser's publication record spans multiple prestigious journals. The frequent publication venues are:

  • Molecular Therapy - Methods & Clinical Development
  • International Journal of Molecular Sciences
  • Frontiers in Genome Editing

Selected recent papers include:

  • Design and Testing of Vector-Producing HEK293T Cells Bearing a Genomic Deletion of the SV40 T Antigen Coding Region (2020, Molecular Therapy - Methods & Clinical Development)
  • CRISPR library screening to develop HEK293-derived cell lines with improved lentiviral vector titers (2023, Frontiers in Genome Editing)
  • In vivo targeting of lentiviral vectors pseudotyped with the Tupaia paramyxovirus H glycoprotein bearing a cell-specific ligand (2021, Molecular Therapy - Methods & Clinical Development)
  • Tagging and Capturing of Lentiviral Vectors Using Short RNAs (2021, International Journal of Molecular Sciences)
  • Full-Spectrum Targeted Mutagenesis in Plant and Animal Cells (2021, International Journal of Molecular Sciences)

Reiser collaborates frequently with other researchers in their field. Notable co-authors include Michael Marino, Brian J. Iaffaldano, Takele Argaw, Anna Kwilas, and Andrew E. Timmons, with multiple shared publications reflecting ongoing collaborative efforts.

Best Publications

  • Transfer of proteins from gels to diazobenzyloxymethyl-paper and detection with antisera: a method for studying antibody specificity and antigen structure

    Jaime Renart;Jakob Reiser;George R. Stark

  • Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa

    Urs A. Ochsner;Jakob Reiser

  • Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors.

    Robert H Kutner;Xian-Yang Zhang;Jakob Reiser;Jakob Reiser

  • [15] Detection of specific RNAs or specific fragments of DNA by fractionation in gels and transfer to diazobenzyloxymethyl paper

    James C. Alwine;David J. Kemp;Barbara A. Parker;Jakob Reiser

  • Altering the tropism of lentiviral vectors through pseudotyping.

    James Cronin;Xian Yang Zhang;Jakob Reiser

  • Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

    Peter Dierks;Albert van Ooyen;Mark D. Cochran;Carl Dobkin

  • Isolation and characterization of a regulatory gene affecting rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa.

    U A Ochsner;A K Koch;A Fiechter;J Reiser

  • Transduction of nondividing cells using pseudotyped defective high-titer HIV type 1 particles

    Jakob Reiser;George Harmison;Stephanie Kluepfel-Stahl;Roscoe O. Brady

  • Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA.

    M. Aebi;H. Hornig;R.A. Padgett;J. Reiser

  • Isolation, characterization, and expression in Escherichia coli of the Pseudomonas aeruginosa rhlAB genes encoding a rhamnosyltransferase involved in rhamnolipid biosurfactant synthesis.

    U.A. Ochsner;A. Fiechter;J. Reiser

  • Hydrocarbon assimilation and biosurfactant production in Pseudomonas aeruginosa mutants.

    A K Koch;O Käppeli;A Fiechter;J Reiser

  • High-Titer Human Immunodeficiency Virus Type 1-Based Vector Systems for Gene Delivery into Nondividing Cells

    Hideki Mochizuki;Joan P. Schwartz;Koichi Tanaka;Roscoe O. Brady

  • Potential of mesenchymal stem cells in gene therapy approaches for inherited and acquired diseases.

    Jakob Reiser;Xian Yang Zhang;Charles S. Hemenway;Debasis Mondal

  • Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit beta-globin gene.

    Berend Wieringa;François Meyer;François Meyer;Jakob Reiser;Charles Weissmann

  • Production and concentration of pseudotyped HIV-1-based gene transfer vectors.

    J Reiser

  • Multifunctional RNA nanoparticles.

    Kirill A. Afonin;Mathias Viard;Alexey Y. Koyfman;Angelica N. Martins

  • Production of Pseudomonas aeruginosa Rhamnolipid Biosurfactants in Heterologous Hosts

    U A Ochsner;J Reiser;A Fiechter;B Witholt

  • Lentiviral vectors for sustained transgene expression in human bone marrow-derived stromal cells.

    Xian Yang Zhang;Vincent F. La Russa;Lili Bao;Jay Kolls

  • Transduction of bone-marrow-derived mesenchymal stem cells by using lentivirus vectors pseudotyped with modified RD114 envelope glycoproteins

    Xian Yang Zhang;Vincent F. La Russa;Jakob Reiser

  • TRIF and IRF-3 Binding to the TNF Promoter Results in Macrophage TNF Dysregulation and Steatosis Induced by Chronic Ethanol

    Xue-Jun Zhao;Qing Dong;Julie Bindas;Jon D. Piganelli

Frequent Co-Authors

Armin Fiechter
Armin Fiechter ETH Zurich
Charles Weissmann
Charles Weissmann University of Florida
Urs A. Ochsner
Urs A. Ochsner University of Colorado Anschutz Medical Campus
Roscoe O. Brady
Roscoe O. Brady Beth Israel Deaconess Medical Center
George R. Stark
George R. Stark Cleveland Clinic
Jay K. Kolls
Jay K. Kolls Tulane University
Nicholas M. Boulis
Nicholas M. Boulis Emory University
Quinn H. Hogan
Quinn H. Hogan Medical College of Wisconsin
Nicolas G. Bazan
Nicolas G. Bazan Louisiana State University
Noël Tordo
Noël Tordo Institut Pasteur

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