World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
10769
World Ranking
14473
National Ranking
171

Overview

Hye-Kyung Na is affiliated with Sungshin Women's University in South Korea, contributing significantly to the fields of medicine and biochemistry. Their research spans a range of topics primarily within molecular biology, pharmacology, and oncology, with a focus on inflammatory processes and cancer-related mechanisms.

The scientist's recent papers include:

  • "Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification" (2020), published in Biochemical Pharmacology
  • "Resveratrol suppresses gastric cancer cell proliferation and survival through inhibition of PIM-1 kinase activity" (2020), published in Archives of Biochemistry and Biophysics
  • "JNK-mediated Ser27 phosphorylation and stabilization of SIRT1 promote growth and progression of colon cancer through deacetylation-dependent activation of Snail" (2021), published in Molecular Oncology
  • "Targeting cyclooxygenase-2 for chemoprevention of inflammation-associated intestinal carcinogenesis: An update" (2024), published in Biochemical Pharmacology
  • "Reprograming of Tumor-Associated Macrophages in Breast Tumor-Bearing Mice under Chemotherapy by Targeting Heme Oxygenase-1" (2021), published in Antioxidants

Their work frequently appears in several key publication venues, including:

  • Journal of Cancer Prevention
  • Archives of Biochemistry and Biophysics
  • Antioxidants
  • Biochemical Pharmacology
  • Cancer Research

Research collaboration is notable with several frequent coauthors such as Young-Joon Surh, Su-Jung Kim, Do-Hee Kim, Seong Hoon Kim, and Soma Saeidi.

Key research topics examined in their work encompass:

  • Inflammatory mediators and NSAID effects
  • NF-κB Signaling Pathways
  • Genomics, phytochemicals, and oxidative stress
  • Pharmacological Effects of Natural Compounds
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Curcumin's Biomedical Applications
  • Heme Oxygenase-1 and Carbon Monoxide

Their publications highlight multi-disciplinary approaches combining molecular biology techniques with pharmacological insights, especially regarding the modulation of cancer progression and inflammation. Their work on natural compounds such as curcumin and resveratrol reflects a focus on phytochemicals and their biomedical applications.

Best Publications

  • Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals.

    Young-Joon Surh;Joydeb Kumar Kundu;Hye-Kyung Na

  • Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG.

    Hye-Kyung Na;Young-Joon Surh

  • Redox-Sensitive Transcription Factors as Prime Targets for Chemoprevention with Anti-Inflammatory and Antioxidative Phytochemicals

    Young-Joon Surh;Joydeb Kumar Kundu;Hye-Kyung Na;Jeong-Sang Lee

  • CURCUMIN ATTENUATES DIMETHYLNITROSAMINE-INDUCED LIVER INJURY IN RATS THROUGH NRF2-MEDIATED INDUCTION OF HEME OXYGENASE-1

    E. Olatunde Farombi;Sangeeta Shrotriya;Hye-Kyung Na;Sung-Hoon Kim

  • (-)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells.

    Hye-Kyung Na;Eun-Hee Kim;Joo-Hee Jung;Hyun-Hee Lee

  • NF-κB and Nrf2 as prime molecular targets for chemoprevention and cytoprotection with anti-inflammatory and antioxidant phytochemicals

    Young-Joon Surh;Hye-Kyung Na

  • Oncogenic potential of Nrf2 and its principal target protein heme oxygenase-1.

    Hye-Kyung Na;Young-Joon Surh

  • Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells.

    Zhi-Hua Chen;Yeon-Jin Hurh;Hye-Kyung Na;Jung-Hwan Kim

  • Transcriptional regulation via cysteine thiol modification: a novel molecular strategy for chemoprevention and cytoprotection.

    Hye-Kyung Na;Young-Joon Surh

  • Inhibition of Phorbol Ester–Induced COX-2 Expression by Epigallocatechin Gallate in Mouse Skin and Cultured Human Mammary Epithelial Cells

    Joydeb Kumar Kundu;Hye-Kyung Na;Kyung-Soo Chun;Young-Kyung Kim

  • Peroxisome proliferator-activated receptor γ (PPARγ) ligands as bifunctional regulators of cell proliferation

    Hye-Kyung Na;Young-Joon Surh

  • Capsaicin induces heme oxygenase-1 expression in HepG2 cells via activation of PI3K-Nrf2 signaling: NAD(P)H:quinone oxidoreductase as a potential target.

    Eun-Joo Joung;Mei-Hua Li;Hee Geum Lee;Nuntiya Somparn;Nuntiya Somparn

  • Nitric oxide induces expression of cyclooxygenase-2 in mouse skin through activation of NF-κB

    Kyung Soo Chun;Hyun Ho Cha;Jun Wan Shin;Hye Kyung Na

  • 15-Deoxy-Δ12,14-prostaglandin J2, an electrophilic lipid mediator of anti-inflammatory and pro-resolving signaling

    Young-Joon Surh;Hye-Kyung Na;Jong-Min Park;Ha-Na Lee

  • Role of Nrf2-mediated heme oxygenase-1 upregulation in adaptive survival response to nitrosative stress.

    Young-Joon Surh;Joydeb Kumar Kundu;Joydeb Kumar Kundu;Mei-Hua Li;Hye-Kyung Na

  • Molecular Basis of Alcohol-Related Gastric and Colon Cancer

    Hye-Kyung Na;Ja Young Lee

  • Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling.

    Mei-Hua Li;Jung-Hee Jang;Hye-Kyung Na;Young-Nam Cha

  • Diallyl trisulfide induces apoptosis in human breast cancer cells through ROS-mediated activation of JNK and AP-1

    Hye-Kyung Na;Eun-Hee Kim;Min-Ah Choi;Jong-Min Park

  • Ginger-derived phenolic substances with cancer preventive and therapeutic potential.

    Joydeb Kumar Kundu;Hye-Kyung Na;Young-Joon Surh

  • Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-κB as a possible target

    Su-Hyeong Kim;Sang-Hyun Song;Sang-Gyun Kim;Kyung-Soo Chun

Frequent Co-Authors

Young-Joon Surh
Young-Joon Surh Seoul National University
Joydeb Kumar Kundu
Joydeb Kumar Kundu Keimyung University
Eunji Lee
Eunji Lee Gwangju Institute of Science and Technology
Dong-Young Noh
Dong-Young Noh Seoul National University
James E. Trosko
James E. Trosko Michigan State University
Kwang Pyo Kim
Kwang Pyo Kim Kyung Hee University
Akira Murakami
Akira Murakami Kyoto University
Chia-Cheng Chang
Chia-Cheng Chang Michigan State University
Jae Weon Kim
Jae Weon Kim Seoul National University
Yong Sang Song
Yong Sang Song Seoul National University

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