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Helen E. Scharfman

Helen E. Scharfman

D-Index & Metrics

Neuroscience

D-Index
85
Citations
24003
World Ranking
1347
National Ranking
678

Overview

Helen E. Scharfman is affiliated with New York University in the United States and has contributed extensively to the field of neuroscience and medicine. Their research focuses on several key areas including cellular and molecular neuroscience, cognitive neuroscience, physiology, developmental neuroscience, and neurology.

The researcher's work spans multiple main fields of study:

  • Neuroscience
  • Medicine

Within these fields, Scharfman has specialized in subfields such as:

  • Cellular and Molecular Neuroscience
  • Cognitive Neuroscience
  • Physiology
  • Developmental Neuroscience
  • Neurology

The main topics covered by their research include:

  • Neuroscience and Neuropharmacology Research
  • Memory and Neural Mechanisms
  • Alzheimer's Disease Research and Treatments
  • Neurogenesis and Neuroplasticity Mechanisms
  • Epilepsy Research and Treatment
  • Sleep and Wakefulness Research
  • Neural Dynamics and Brain Function

Scharfman has published frequently in several scientific journals and platforms. The most common publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Hippocampus
  • eLife
  • Journal of Neuroscience
  • Neurobiology of Disease

Notable recent papers authored or co-authored by Scharfman include:

  • Assessments of dentate gyrus function: discoveries and debates, 2023, Nature Reviews Neuroscience
  • Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity, 2023, Neuron
  • Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy, 2022, Neuron
  • Bidirectional Regulation of Cognitive and Anxiety-like Behaviors by Dentate Gyrus Mossy Cells in Male and Female Mice, 2021, Journal of Neuroscience
  • Dorsal and ventral mossy cells differ in their axonal projections throughout the dentate gyrus of the mouse hippocampus, 2021, Hippocampus

Scharfman collaborates regularly with several researchers, including:

  • Justin J. Botterill
  • John J. LaFrancois
  • Swati Jain
  • Christos Panagiotis Lisgaras
  • David Alcantara-Gonzalez

Best Publications

  • Brain-derived Neurotrophic Factor

    Devin K. Binder;Helen E. Scharfman

  • The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies).

    David G. Amaral;Helen E. Scharfman;Pierre Lavenex

  • Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats.

    Helen Scharfman;Jeffrey Goodman;Adam Macleod;Sudar Phani

  • Dynamics of Active Sensing and perceptual selection

    Charles E. Schroeder;Charles E. Schroeder;Dulaney A. Wilson;Dulaney A. Wilson;Dulaney A. Wilson;Thomas Radman;Helen Scharfman;Helen Scharfman

  • Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: functional implications of seizure-induced neurogenesis.

    Helen E. Scharfman;Jeffrey H. Goodman;Anne L. Sollas

  • The Neurobiology of Epilepsy

    Helen E. Scharfman

  • BDNF and epilepsy: too much of a good thing?

    Devin K Binder;Susan D Croll;Christine M Gall;Helen E Scharfman

  • Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline.

    Kyung Ok Cho;Zane R. Lybrand;Naoki Ito;Rebecca Brulet

  • Brain-Derived Neurotrophic Factor Transgenic Mice Exhibit Passive Avoidance Deficits, Increased Seizure Severity and In Vitro Hyperexcitability in the Hippocampus and Entorhinal Cortex

    S.D. Croll;C. Suri;D.L. Compton;M.V. Simmons

  • Estrogen and brain-derived neurotrophic factor (BDNF) in hippocampus: complexity of steroid hormone-growth factor interactions in the adult CNS.

    Helen E. Scharfman;Neil J. MacLusky

  • proBDNF Negatively Regulates Neuronal Remodeling, Synaptic Transmission, and Synaptic Plasticity in Hippocampus

    Jianmin Yang;Lauren C. Harte-Hargrove;Chia-Jen Siao;Tina Marinic

  • The CA3 "backprojection" to the dentate gyrus.

    Helen E. Scharfman

  • The enigmatic mossy cell of the dentate gyrus

    Unknown

  • Hippocampal excitability increases during the estrous cycle in the rat: a potential role for brain-derived neurotrophic factor.

    Helen E. Scharfman;Thomas C. Mercurio;Jeffrey H. Goodman;Marlene A. Wilson

  • Protection of dentate hilar cells from prolonged stimulation by intracellular calcium chelation

    Helen E. Scharfman;Philip A. Schwartzkroin

  • Electrophysiological evidence that dentate hilar mossy cells are excitatory and innervate both granule cells and interneurons.

    H. E. Scharfman

  • The Influence of Gonadal Hormones on Neuronal Excitability, Seizures, and Epilepsy in the Female

    Helen E. Scharfman;Neil J. MacLusky

  • Hilar mossy cells of the dentate gyrus: a historical perspective.

    Helen E. Scharfman;Helen E. Scharfman;Catherine E. Myers;Catherine E. Myers

  • Spontaneous Limbic Seizures after Intrahippocampal Infusion of Brain-Derived Neurotrophic Factor

    Helen E. Scharfman;Jeffrey H. Goodman;Anne L. Sollas;Susan D. Croll

  • Synaptic connections of dentate granule cells and hilar neurons: results of paired intracellular recordings and intracellular horseradish peroxidase injections.

    H. E. Scharfman;D. D. Kunkel;Philip A Schwartzkroin

  • DENTATE HILAR CELLS WITH DENDRITES IN THE MOLECULAR LAYER HAVE LOWER THRESHOLDS FOR SYNAPTIC ACTIVATION BY PERFORANT PATH THAN GRANULE CELLS

    HE Scharfman

Frequent Co-Authors

Jeffrey H. Goodman
Jeffrey H. Goodman SUNY Downstate Medical Center
Philip A. Schwartzkroin
Philip A. Schwartzkroin University of California, Davis
Neil J. MacLusky
Neil J. MacLusky University of Guelph
Peter Lakatos
Peter Lakatos Nathan Kline Institute for Psychiatric Research
Devin K. Binder
Devin K. Binder University of California, Riverside
Christine M. Gall
Christine M. Gall University of California, Irvine
Charles E. Schroeder
Charles E. Schroeder Nathan Kline Institute for Psychiatric Research
Robert S. Sloviter
Robert S. Sloviter University of Arizona
Marlene A. Wilson
Marlene A. Wilson University of South Carolina
Abraham A. Palmer
Abraham A. Palmer University of California, San Diego

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