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Gerald Seifert

Gerald Seifert

D-Index & Metrics

Neuroscience

D-Index
46
Citations
9700
World Ranking
6635
National Ranking
561

Overview

Gerald Seifert is affiliated with the University of Bonn in Germany and has produced extensive research within the fields of neuroscience and biochemistry, genetics, and molecular biology. Their work primarily focuses on cellular and molecular neuroscience, with specific attention to molecular biology, neurology, developmental neuroscience, and biophysics.

Their research investigates critical topics including neuroscience and neuropharmacology research, connexins and lens biology, neuroinflammation and neurodegeneration mechanisms, neurogenesis and neuroplasticity mechanisms, ion channel regulation and function, barrier structure and function studies, and heat shock proteins research.

The scientist's recent publications demonstrate a focused investigation into the role of astrocytes, microglia, and connexins in neurological disorders such as epilepsy. Notable papers include:

  • Reactive microglia are the major source of tumor necrosis factor alpha and contribute to astrocyte dysfunction and acute seizures in experimental temporal lobe epilepsy, 2022, Glia
  • Astrocytes and oligodendrocytes in the thalamus jointly maintain synaptic activity by supplying metabolites, 2021, Cell Reports
  • Constitutive deletion of astrocytic connexins aggravates kainate-induced epilepsy, 2020, Glia
  • Cx43 carboxyl terminal domain determines AQP4 and Cx30 endfoot organization and blood brain barrier permeability, 2021, Scientific Reports
  • Cell death of hippocampal CA1 astrocytes during early epileptogenesis, 2021, Epilepsia

Several coauthors frequently collaborate with Gerald Seifert, including Christian Steinhäuser, Ronald Jabs, Aline Timmermann, Christian Henneberger, and Lukas Henning. These collaborations underscore a continued focus on neuroglia and neurological disease mechanisms.

Their publications appear predominantly in specialized venues such as Glia, bioRxiv (Cold Spring Harbor Laboratory), Neurochemical Research, Cell Reports, and Scientific Reports, reflecting a consistent engagement within neuroscience and cellular biology research circles.

Best Publications

  • Astrocyte dysfunction in neurological disorders: a molecular perspective

    Gerald Seifert;Karl Schilling;Christian Steinhäuser

  • Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate

    Paola Bezzi;Vidar Gundersen;Vidar Gundersen;José Luis Galbete;Gerald Seifert

  • Viscoelastic properties of individual glial cells and neurons in the CNS

    Yun-Bi Lu;Kristian Franze;Gerald Seifert;Christian Steinhäuser

  • Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus.

    Katja Matthias;Frank Kirchhoff;Gerald Seifert;Kerstin Hüttmann

  • Connexin 47 (Cx47)-Deficient Mice with Enhanced Green Fluorescent Protein Reporter Gene Reveal Predominant Oligodendrocytic Expression of Cx47 and Display Vacuolized Myelin in the CNS

    Benjamin Odermatt;Kerstin Wellershaus;Anke Wallraff;Gerald Seifert

  • Astrocytes in the hippocampus of patients with temporal lobe epilepsy display changes in potassium conductances

    Stefan Hinterkeuser;Wolfgang Schröder;Gerhard Hager;Gerald Seifert

  • Astrocyte dysfunction in epilepsy

    Gerald Seifert;Giorgio Carmignoto;Christian Steinhäuser

  • Analysis of Astroglial K+ Channel Expression in the Developing Hippocampus Reveals a Predominant Role of the Kir4.1 Subunit

    Gerald Seifert;Kerstin Hüttmann;Devin K. Binder;Christian Hartmann

  • Astrocyte dysfunction in temporal lobe epilepsy: K+ channels and gap junction coupling.

    Christian Steinhäuser;Gerald Seifert;Peter Bedner

  • Developmental regulation of Na+ and K+ conductances in glial cells of mouse hippocampal brain slices

    Klaus Kressin;Elena Kuprijanova;Ronald Jabs;Gerald Seifert

  • Neuron-astrocyte signaling and epilepsy.

    Gerald Seifert;Christian Steinhäuser

  • Glial cells in the mouse hippocampus express AMPA receptors with an intermediate Ca2+ permeability.

    Gerald Seifert;Christian Steinhäuser

  • Connexin expression by radial glia-like cells is required for neurogenesis in the adult dentate gyrus

    Albrecht Kunze;Marga Rubenecia Congreso;Christian Hartmann;Anke Wallraff-Beck

  • Functional and molecular properties of human astrocytes in acute hippocampal slices obtained from patients with temporal lobe epilepsy.

    Wolfgang Schroder;Stefan Hinterkeuser;Gerald Seifert;Johannes Schramm

  • Glial membrane channels and receptors in epilepsy: impact for generation and spread of seizure activity.

    Christian Steinhäuser;Gerald Seifert

  • Astrocytic function and its alteration in the epileptic brain.

    Ronald Jabs;Gerald Seifert;Christian Steinhäuser

  • Panglial Gap Junctional Communication is Essential for Maintenance of Myelin in the CNS

    Oliver Tress;Marta Maglione;Dennis May;Tatjyana Pivneva

  • NG2‐expressing cells in the nervous system revealed by the NG2‐EYFP‐knockin mouse

    Khalad Karram;Sandra Goebbels;Markus Schwab;Katja Jennissen

  • Ionotropic glutamate receptors in astrocytes

    Gerald Seifert;Christian Steinhäuser

  • Characterization of Panglial Gap Junction Networks in the Thalamus, Neocortex, and Hippocampus Reveals a Unique Population of Glial Cells

    Stephanie Griemsmann;Simon P. Höft;Peter Bedner;Jiong Zhang

Frequent Co-Authors

Christian Steinhäuser
Christian Steinhäuser University of Bonn
Martin Theis
Martin Theis Columbia University
Christine R. Rose
Christine R. Rose Heinrich Heine University Düsseldorf
Helmut Kettenmann
Helmut Kettenmann Shenzhen Institutes of Advanced Technology
Hans-Christian Pape
Hans-Christian Pape University of Münster
Etienne Audinat
Etienne Audinat University of Montpellier
Frank Kirchhoff
Frank Kirchhoff University of Ulm
Andrea Volterra
Andrea Volterra University of Lausanne
Richard D. Kolodner
Richard D. Kolodner University of California, San Diego

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