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Floris P. J. T. Rutjes

Floris P. J. T. Rutjes

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Chemistry
Netherlands
2025

D-Index & Metrics

Chemistry

D-Index
74
Citations
19381
World Ranking
4702
National Ranking
113

Research.com Recognitions

  • 2025 - Research.com Chemistry in Netherlands Leader Award
  • 2022 - Research.com Chemistry in Netherlands Leader Award

Overview

Floris P. J. T. Rutjes is affiliated with Radboud University in the Netherlands and has contributed extensively to the fields of Biochemistry, Genetics and Molecular Biology, as well as Chemistry. Their research spans multiple subfields including Molecular Biology, Materials Chemistry, Organic Chemistry, Spectroscopy, and Biomedical Engineering.

The scientist's work covers a range of main topics, among which are:

  • Crystallization and Solubility Studies
  • Chemical Synthesis and Analysis
  • X-ray Diffraction in Crystallography
  • Click Chemistry and Applications
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Analytical Chemistry and Chromatography
  • Metabolomics and Mass Spectrometry Studies

Rutjes has published frequently in several scientific venues, notably:

  • The Cambridge Structural Database
  • Chemistry - A European Journal
  • Journal of the American Chemical Society
  • European Journal of Organic Chemistry
  • ChemMedChem

Recent papers authored or co-authored by Rutjes include:

  • "Cyclobutanes in Small-Molecule Drug Candidates," 2022, ChemMedChem
  • "Characterization of glycosyl dioxolenium ions and their role in glycosylation reactions," 2020, Nature Communications
  • "Continuous one-flow multi-step synthesis of active pharmaceutical ingredients," 2020, Reaction Chemistry & Engineering
  • "Untargeted metabolomics and infrared ion spectroscopy identify biomarkers for pyridoxine-dependent epilepsy," 2021, Journal of Clinical Investigation
  • "Synthetic pathways to tetrahydrocannabinol (THC): an overview," 2020, Organic & Biomolecular Chemistry

The scientist has frequently collaborated with several co-authors, including:

  • Thomas J. Boltje
  • Paul Tinnemans
  • Daniel Blanco-Ania
  • Jonathan Martens
  • Jos Oomens

Rutjes has also contributed to book publications, such as in the Doctor honoris causa series, with the title "Honorary Doctorate Dr. Katalin Karikó" published in 2023.

Best Publications

  • Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three‐Dimensional Imaging of Living Cells

    Jan Dommerholt;Samuel Schmidt;Rinske Temming;Linda J. A. Hendriks

  • Bioconjugation with strained alkenes and alkynes.

    Marjoke F. Debets;Sander S. van Berkel;Jan Dommerholt;A. (Ton) J. Dirks

  • Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition.

    Marjoke F. Debets;Sander S. van Berkel;Sanne Schoffelen;Floris P. J. T. Rutjes

  • Organocatalysed asymmetric Mannich reactions.

    Jorge M. M. Verkade;Lieke J. C. van Hemert;Peter J. L. M. Quaedflieg;Floris P. J. T. Rutjes

  • Polymeric vesicles in biomedical applications

    René P. Brinkhuis;Floris P. J. T. Rutjes;Jan C. M. van Hest

  • Strain-Promoted 1,3-Dipolar Cycloaddition of Cycloalkynes and Organic Azides

    Jan Dommerholt;Floris P. J. T. Rutjes;Floris L. van Delft

  • Azide: a unique dipole for metal-free bioorthogonal ligations.

    Marjoke F. Debets;Christianus W. J. van der Doelen;Floris P. J. T. Rutjes;Floris L. van Delft

  • Polymersome colloidosomes for enzyme catalysis in a biphasic system.

    Zhipeng Wang;Matthijs C M van Oers;Floris P J T Rutjes;Jan C M van Hest

  • Metal‐Free Triazole Formation as a Tool for Bioconjugation

    Sander S. van Berkel;A. (Ton) J. Dirks;Marjoke F. Debets;Floris L. van Delft

  • Expedient synthesis of triazole-linked glycosyl amino acids and peptides.

    B.H.M. Kuijpers;S. Groothuys;A.R. Keereweer;P.J.L.M. Quaedflieg

  • Viedma ripening: a reliable crystallisation method to reach single chirality

    Leyla-Cann Sögütoglu;René R. E. Steendam;Hugo Meekes;Elias Vlieg

  • Enamide-olefin ring-closing metathesis.

    Sape S. Kinderman;Jan H. van Maarseveen;Hans E. Schoemaker;and Henk Hiemstra

  • Ruthenium-catalyzed ring closing olefin metathesis of non-natural α-amino acids

    Floris P.J.T. Rutjes;Hans E. Schoemaker

  • Synthesis of isoxazoles by hypervalent iodine-induced cycloaddition of nitrile oxides to alkynes

    Anup M. Jawalekar;Erik Reubsaet;Floris P. J. T. Rutjes;Floris L. van Delft

  • In situ phosphine oxide reduction: a catalytic Appel reaction.

    Henri A. van Kalkeren;Stefan H. A. M. Leenders;C. Rianne A. Hommersom;Floris P. J. T. Rutjes

  • Recent advances in enzymatic and chemical deracemisation of racemic compounds

    Michał Rachwalski;Niek Vermue;Floris P. J. T. Rutjes

  • Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3 + 2] dipolar cycloaddition reaction

    A. J. (Ton) Dirks;Sander S. van Berkel;Nikos S. Hatzakis;Joost A. Opsteen

  • Total Synthesis of Brevetoxin B. 2. Completion

    K. C. Nicolaou;F. P. J. T. Rutjes;E. A. Theodorakis;J. Tiebes

  • A Microfluidic High-Resolution NMR Flow Probe

    Jacob Bart;Ard J Kolkman;Anna Jo Oosthoek-de Vries;Kaspar Koch

  • Bioorthogonal labelling of biomolecules: new functional handles and ligation methods

    Marjoke F. Debets;Jan C. M. van Hest;Floris P. J. T. Rutjes

  • Recent Advances in Asymmetric Isocyanide-Based Multicomponent Reactions

    Sander S. van Berkel;Berry G. M. Bögels;Marloes A. Wijdeven;Bernhard Westermann;Bernhard Westermann

  • 2-Deoxystreptamine : Central scaffold of aminoglycoside antibiotics

    Guuske F. Busscher;Floris P. J. T. Rutjes;Floris L. van Delft

Frequent Co-Authors

Floris L. van Delft
Floris L. van Delft Wageningen University & Research
Henk Hiemstra
Henk Hiemstra University of Amsterdam
Jan C. M. van Hest
Jan C. M. van Hest Eindhoven University of Technology
Hans E. Schoemaker
Hans E. Schoemaker DSM (Netherlands)
F. Matthias Bickelhaupt
F. Matthias Bickelhaupt Vrije Universiteit Amsterdam
Roeland J. M. Nolte
Roeland J. M. Nolte Radboud University
Joost Schalkwijk
Joost Schalkwijk Radboud University
Jeroen J. L. M. Cornelissen
Jeroen J. L. M. Cornelissen University of Twente
K. C. Nicolaou
K. C. Nicolaou Rice University
Emmanuel A. Theodorakis
Emmanuel A. Theodorakis University of California, San Diego

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