Ezio Giacobini

Overview

Best Publications

• Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment.

  B. Winblad;K. Palmer;Miia Kivipelto;V. Jelic

  5983
  Citations

• The cholinergic system in the pathophysiology and treatment of Alzheimer's disease.

  Harald Hampel;M.-Marsel Mesulam;A Claudio Cuello;Martin R Farlow

  1787
  Citations

• Sex differences in Alzheimer disease — the gateway to precision medicine

  Maria Teresa Ferretti;Maria Florencia Iulita;Enrica Cavedo;Patrizia Andrea Chiesa

  934
  Citations

• Cognitive dysfunction in HIV patients despite long-standing suppression of viremia.

  Samanta Simioni;Matthias Cavassini;Jean Marie Annoni;Aline Rimbault Abraham

  865
  Citations

• Clinical trials and late-stage drug development for Alzheimer's disease : an appraisal from 1984 to 2014

  Lon S. Schneider;Francesca Mangialasche;Francesca Mangialasche;Niels Andreasen;Niels Andreasen;Howard Feldman

  832
  Citations

• Cholinesterase inhibitors: new roles and therapeutic alternatives

  Ezio Giacobini

  729
  Citations

• Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers

  Giovanni B Frisoni;Marina Boccardi;Frederik Barkhof;Kaj Blennow;Kaj Blennow

  651
  Citations

• Alzheimer disease therapy—moving from amyloid-β to tau

  Ezio Giacobini;Gabriel Gold

  578
  Citations

• Cholinesterases: new roles in brain function and in Alzheimer's disease.

  Ezio Giacobini

  468
  Citations

• Cholinergic function and Alzheimer's disease.

  Ezio Giacobini

  380
  Citations

• Revisiting the Cholinergic Hypothesis in Alzheimer's Disease: Emerging Evidence from Translational and Clinical Research

  Harald Hampel;M.-M. Mesulam;A. C. Cuello;A. S. Khachaturian

  352
  Citations

• A cytochemical study of the localization of carbonic anhydrase in the nervous system.

  Ezio Giacobini

  298
  Citations

• Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit.

  Ezio Giacobini;R Spiegel;A Enz;A E Veroff

  280
  Citations

• Mechanisms of cholinesterase inhibition in senile dementia of the alzheimer type: Clinical, pharmacological, and therapeutic aspects

  Robert E. Becker;Ezio Giacobini

  277
  Citations

• Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: from tacrine to future applications.

  Ezio Giacobini

  267
  Citations

• A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease.

  Debomoy K. Lahiri;Martin R. Farlow;Kumar Sambamurti;Nigel H. Greig

  255
  Citations

• Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein.

  A. Wevers;L. Monteggia;S. Nowacki;W. Bloch

  230
  Citations

• Reality orientation therapy combined with cholinesterase inhibitors in Alzheimer's disease: randomised controlled trial

  Graziano Onder;Orazio Zanetti;Ezio Giacobini;Giovanni B. Frisoni

  226
  Citations

• Effects of local and repeated systemic administration of (-)nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex.

  K. L. Summers;E. Giacobini

  221
  Citations

• Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease.

  Hannsjo¨rg Schro¨der;Ezio Giacobini;Robert G. Struble;Karl Zilles

  219
  Citations