World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
58
Citations
12244
World Ranking
4166
National Ranking
1886

Research.com Recognitions

  • 1984 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1983 - Member of the National Academy of Medicine (NAM)
  • 1983 - Member of the National Academy of Sciences

Overview

Dominick P. Purpura was affiliated with the Albert Einstein College of Medicine in the United States. Their research primarily centered on neuroscience, with notable contributions in cellular and molecular neuroscience as well as biochemistry, genetics, and molecular biology.

Their work spanned multiple subfields, including:

  • Cellular and Molecular Neuroscience
  • Molecular Biology
  • Cognitive Neuroscience
  • Developmental Neuroscience
  • Physiology

The main research topics they addressed included:

  • Neuroscience and Neuropharmacology Research
  • Photoreceptor and Optogenetics Research
  • Neurogenesis and Neuroplasticity Mechanisms
  • Memory and Neural Mechanisms
  • Genetics and Neurodevelopmental Disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • RNA Research and Splicing

Dominick P. Purpura published extensively, with frequent appearances in venues such as bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, Cell Reports, Neuron, and eLife.

Among the recent publications were:

  • "Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals" (2022, Neuron)
  • "Altered synaptic connectivity and brain function in mice lacking microglial adapter protein Iba1" (2021, Proceedings of the National Academy of Sciences)
  • "Maintenance of a short-lived protein required for long-term memory involves cycles of transcription and local translation" (2023, Neuron)
  • "Modulation of NMDA Receptors by G-protein-coupled receptors: Role in Synaptic Transmission, Plasticity and Beyond" (2020, Neuroscience)
  • "Presynaptic NMDA receptors facilitate short-term plasticity and BDNF release at hippocampal mossy fiber synapses" (2021, eLife)

The scientist collaborated frequently with several coauthors, including:

  • Pablo J. Lituma
  • Kaoutsar Nasrallah
  • Robert H. Singer
  • Stefano Lutzu
  • Hannah R. Monday

Dominick P. Purpura's professional recognitions included election as a Fellow of the American Association for the Advancement of Science (AAAS) in 1984, membership in the National Academy of Sciences (1983), and membership in the National Academy of Medicine (NAM) in 1983.

Best Publications

  • NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

    C. Geoffrey Lau;R. Suzanne Zukin

  • Dendritic spine "dysgenesis" and mental retardation

    Dominick P. Purpura

  • Distortion of neuronal geometry and formation of aberrant synapses in neuronal storage disease

    Dominick P. Purpura;Kinuko Suzuki

  • The neural substrates of rapid-onset Dystonia-Parkinsonism

    D Paola Calderon;Rachel Fremont;Franca Kraenzlin;Kamran Khodakhah

  • REST-dependent epigenetic remodeling promotes the developmental switch in synaptic NMDA receptors

    Alma Rodenas-Ruano;Andrés E Chávez;Maria J Cossio;Pablo E Castillo

  • QUANTITATIVE ASPECTS OF CO2 FIXATION IN MAMMALIAN BRAIN IN VIVO.

    H. Waelsch;S. Berl;C. A. Rossi;D. D. Clarke

  • Normal and aberrant neuronal development in the cerebral cortex of human fetus and young infant.

    Dominick P. Purpura

  • Intracellular recording from thalamic neurons during recruiting responses.

    Unknown

  • Meganeurites and other aberrant processes of neurons in feline GM1-gangliosidosis: a Golgi study.

    Dominick P. Purpura;Dominick P. Purpura;Henry J. Baker;Henry J. Baker

  • Intracellular studies of the corpus striatum I. Synaptic potentials and discharge characteristics of caudate neurons activated by thalamic stimulation

    Dominick P. Purpura;Alberto Malliani

  • Autism, fever, epigenetics and the locus coeruleus.

    Mark F. Mehler;Dominick P. Purpura

  • Abnormal High-Frequency Burst Firing of Cerebellar Neurons in Rapid-Onset Dystonia-Parkinsonism

    Rachel Fremont;D. Paola Calderon;Sara Maleki;Kamran Khodakhah

  • Electron microscope study of development of cat superficial neocortex.

    Unknown

  • Postsynaptic potentials and spike variations in the feline hippocampus during postnatal ontogenesis.

    Dominick P. Purpura;Stanislav Prelevic;Maurizio Santini

  • Pharmacological reversal of synaptic plasticity deficits in the mouse model of Fragile X syndrome by group II mGluR antagonist or lithium treatment

    Catherine H. Choi;Brian P. Schoenfeld;Aaron J. Bell;Paul Hinchey

  • Intracellular studies of the corpus striatum II. Patterns of synaptic activities in lenticular and entopeduncular neurons

    Alberto Malliani;Dominick P. Purpura

  • Fine structure of meganeurites and secondary growth processes in feline GM1-gangliosidosis.

    Dominick P. Purpura;Dominick P. Purpura;George D. Pappas;George D. Pappas;Henry J. Baker;Henry J. Baker

  • Ectopic dendritic growth in mature pyramidal neurones in human ganglioside storage disease.

    Dominick P. Purpura

  • Ultrastructure of neurites and meganeurites of cortical pyramidal neurons in feline gangliosidosis as revealed by the combined Golgi-EM technique

    S.U. Walkley;S. Wurzelmann;D.P. Purpura

  • Comparative Ontogensis of Structure-Function Relations in Cerebral and Cerebeller Cortex

    Unknown

  • Chronic GM1 gangliosidosis presenting as dystonia: I. Clinical and pathological features

    James E. Goldman;David Katz;Isabelle Rapin;Dominick P. Purpura

  • Fine structure of neurons and synapses in the feline hippocampus during postnatal ontogenesis

    Ilsa R. Schwartz;George D. Pappas;Dominick P. Purpura

  • Synaptic convergence of cerebellar and lenticular projections to thalamus.

    T. Desiraju;D.P. Purpura

  • Laminar distribution of geniculo-cortical afferents in visual cortex of the postnatal kitten

    Lois Laemle;Christiane Benhamida;Dominick P. Purpura

  • Morphological and physiological properties of chronically isolated immature neocortex.

    Unknown

  • Physiological basis of the alpha rhythm

    Dominick P. Purpura

Frequent Co-Authors

Mark F. Mehler
Mark F. Mehler Albert Einstein College of Medicine
Alan Cowey
Alan Cowey University of Oxford
Rodolfo R. Llinás
Rodolfo R. Llinás New York University
Tomas Hökfelt
Tomas Hökfelt Karolinska Institute
Floyd E. Bloom
Floyd E. Bloom Scripps Research Institute

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