Diana G. Myles

Overview

Best Publications

• A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion.

  Carl P. Blobel;Tyra G. Wolfsberg;Christoph W. Turck;Diana G. Myles

  921
  Citations

• The ADAM gene family: surface proteins with adhesion and protease activity.

  Paul Primakoff;Diana G Myles

  855
  Citations

• Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor.

  Eduardo A. C. Almeida;A. P.J. Huovila;A. E. Sutherland;L. E. Stephens

  700
  Citations

• ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain.

  Tyra G. Wolfsberg;Paul D. Straight;Robyn L. Gerena;Ari-Pekka J. Huovila

  543
  Citations

• Penetration, adhesion, and fusion in mammalian sperm-egg interaction.

  Paul Primakoff;Diana G. Myles

  472
  Citations

• A hyaluronidase activity of the sperm plasma membrane protein PH-20 enables sperm to penetrate the cumulus cell layer surrounding the egg.

  Ying Lin;Kimberly Mahan;William E Lathrop;Diana G. Myles

  416
  Citations

• Fully effective contraception in male and female guinea pigs immunized with the sperm protein PH-20.

  Paul Primakoff;William Lathrop;Laura Woolman;Ann Cowan

  362
  Citations

• Analysis of loss of adhesive function in sperm lacking cyritestin or fertilin beta.

  Hitoshi Nishimura;Chunghee Cho;Daniel R. Branciforte;Diana G. Myles

  360
  Citations

• Cell adhesion and fertilization: steps in oocyte transport, sperm-zona pellucida interactions, and sperm-egg fusion.

  Prudence Talbot;Barry D. Shur;Diana G. Myles

  346
  Citations

• Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion

  Diana G. Myles;Lida H. Kimmel;Carl P. Blobel;Judith M. White

  342
  Citations

• A role for the migrating sperm surface antigen PH-20 in guinea pig sperm binding to the egg zona pellucida.

  P Primakoff;H Hyatt;D G Myles

  340
  Citations

• A Role for the Disintegrin Domain of Cyritestin, a Sperm Surface Protein Belonging to the ADAM Family, in Mouse Sperm–Egg Plasma Membrane Adhesion and Fusion

  Ruiyong Yuan;Paul Primakoff;Diana G. Myles

  324
  Citations

• Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence.

  C P Blobel;D G Myles;P Primakoff;J M White

  296
  Citations

• The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications

  T G Wolfsberg;J F Bazan;C P Blobel;D G Myles

  261
  Citations

• Normal Fertilization Occurs with Eggs Lacking the Integrin α6β1 and Is Cd9-Dependent

  Brent J. Miller;Elisabeth Georges-Labouesse;Paul Primakoff;Diana G. Myles

  249
  Citations

• Evidence that proteolysis of the surface is an initial step in the mechanism of formation of sperm cell surface domains.

  B M Phelps;D E Koppel;P Primakoff;D G Myles

  239
  Citations

• Oocyte CD9 is enriched on the microvillar membrane and required for normal microvillar shape and distribution

  Kathryn E. Runge;James E. Evans;Zhi Yong He;Surabhi Gupta

  238
  Citations

• Why did the sperm cross the cumulus? To get to the oocyte. Functions of the sperm surface proteins PH-20 and fertilin in arriving at, and fusing with, the egg.

  Diana G. Myles;Paul Primakoff

  235
  Citations

• cDNA cloning reveals the molecular structure of a sperm surface protein, PH-20, involved in sperm-egg adhesion and the wide distribution of its gene among mammals

  William E Lathrop;Ellen P. Carmichael;Diana G. Myles;Paul Primakoff

  231
  Citations

• Restricted lateral diffusion of PH-20, a PI-anchored sperm membrane protein.

  Bonnie M. Phelps;Paul Primakoff;Dennis E. Koppel;Martin G. Low

  218
  Citations