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Chemistry

D-Index
63
Citations
13059
World Ranking
8498
National Ranking
2440

Research.com Recognitions

  • 2015 - Chirality Medal, Società Chimica Italiana
  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2010 - Fellow of the American Chemical Society

Overview

Christopher J. Welch is affiliated with the Indiana Consortium for Analytical Science & Engineering in the United States. Their research spans multiple scientific fields and focuses significantly on analytical techniques, molecular biology, and engineering.

The primary fields of study associated with their work include:

  • Chemistry
  • Biochemistry, Genetics and Molecular Biology
  • Engineering

Their research covers several subfields, particularly:

  • Spectroscopy
  • Biomedical Engineering
  • Molecular Biology
  • Analytical Chemistry
  • Cell Biology

Key topics in their scientific output are:

  • Analytical Chemistry and Chromatography
  • Mass Spectrometry Techniques and Applications
  • Microfluidic and Capillary Electrophoresis Applications
  • Advanced Chemical Sensor Technologies
  • Metabolomics and Mass Spectrometry Studies
  • Spectroscopy and Chemometric Analyses
  • Molecular spectroscopy and chirality

Their work has been published frequently in various venues, notably:

  • Analytical Chemistry
  • UNC Libraries
  • Chirality
  • The Journal of Organic Chemistry
  • SSRN Electronic Journal

Recent notable papers authored or co-authored by Christopher J. Welch include:

  • High-Throughput Determination of Enantiopurity by Microplate Circular Dichroism, 2020, The Journal of Organic Chemistry
  • 3DMolMS: prediction of tandem mass spectra from 3D molecular conformations, 2023, Bioinformatics
  • Enhanced Structure-Based Prediction of Chiral Stationary Phases for Chromatographic Enantioseparation from 3D Molecular Conformations, 2024, Analytical Chemistry
  • Quantitation of Trastuzumab and an Antibody to SARS-CoV-2 in Minutes Using Affinity Membranes in 96-Well Plates, 2022, Analytical Chemistry
  • Next-Generation TLC: A Quantitative Platform for Parallel Spotting and Imaging, 2020, The Journal of Organic Chemistry

Frequent collaborators in their research include:

  • Klaus M. Hahn
  • R. Graham Cooks
  • Merlin L. Bruening
  • Lingqi Qiu
  • Andreas Kaerner

Recognition for their contributions includes the following awards:

  • Chirality Medal, Società Chimica Italiana, 2015
  • Fellow of the American Association for the Advancement of Science (AAAS), 2012
  • Fellow of the American Chemical Society, 2010

Best Publications

  • Nanomole-scale high-throughput chemistry for the synthesis of complex molecules

    Alexander Buitrago Santanilla;Erik L. Regalado;Tony Pereira;Michael Shevlin

  • Greening analytical chromatography

    Christopher J. Welch;Naijun Wu;Mirlinda Biba;Robert Hartman

  • Evolution of chiral stationary phase design in the Pirkle laboratories

    Christopher J. Welch

  • Design, synthesis, and evaluation of an improved enantioselective naproxen selector

    William H. Pirkle;Christopher J. Welch;Bo Lamm

  • Adsorbent Screening for Metal Impurity Removal in Pharmaceutical Process Research

    Christopher J. Welch;Jennifer Albaneze-Walker, ,†;William R. Leonard;Mirlinda Biba

  • Mapping the dark space of chemical reactions with extended nanomole synthesis and MALDI-TOF MS.

    Shishi Lin;Sergei Dikler;William D. Blincoe;Ronald D. Ferguson

  • Efficient Synthesis of NK1 Receptor Antagonist Aprepitant Using a Crystallization-Induced Diastereoselective Transformation†

    Karel M. J. Brands;Joseph F. Payack;Jonathan D. Rosen;Todd D. Nelson

  • Experimental Limiting Oxygen Concentrations for Nine Organic Solvents at Temperatures and Pressures Relevant to Aerobic Oxidations in the Pharmaceutical Industry

    Paul M. Osterberg;Jeffry K. Niemeier;Christopher J. Welch;Joel M. Hawkins

  • An Improved Chiral Stationary Phase for the Chromatographic Separation of Underivatized Naproxen Enantiomers

    William H. Pirkle;Christopher J. Welch

  • Progress in the design of selectors for buckminsterfullerene

    Christopher J. Welch;William H. Pirkle

  • Human class Mu glutathione transferases, in particular isoenzyme M2-2,catalyze detoxication of the dopamine metabolite aminochrome

    Juan Segura-Aguilar;Sofia Baez;Mikael Widersten;Christopher J. Welch

  • Metabolic activation of dopamine o-quinones to o-semiquinones by NADPH cytochrome P450 reductase may play an important role in oxidative stress and apoptotic effects

    Juan Segura-Aguilar;Diana Metodiewa;Christopher J Welch

  • Mass Activated Droplet Sorting (MADS) Enables High-Throughput Screening of Enzymatic Reactions at Nanoliter Scale

    Daniel A. Holland‐Moritz;Michael K. Wismer;Benjamin F. Mann;Iman Farasat

  • Ultrafast chiral separations for high throughput enantiopurity analysis

    Chandan L. Barhate;Chandan L. Barhate;Leo A. Joyce;Alexey A. Makarov;Kerstin Zawatzky

  • Use of simultaneous face to face and face to edge π-π interactions to facilitate chiral recognition

    William H. Pirkle;Christopher J. Welch

  • Analytical Method Volume Intensity (AMVI): A green chemistry metric for HPLC methodology in the pharmaceutical industry

    R. Hartman;R. Helmy;M. Al-Sayah;Christopher J. Welch

  • Chromatographic separation of the enantiomers of acylated amines on chiral stationary phases

    William H. Pirkle;Christopher J. Welch

  • Ultrafast Chiral Chromatography as the Second Dimension in Two-Dimensional Liquid Chromatography Experiments.

    Chandan L. Barhate;Erik L. Regalado;Nathan D. Contrella;Joon Lee

  • Current challenges and future prospects in chromatographic method development for pharmaceutical research

    Frederick T. Mattrey;Alexey A. Makarov;Erik L. Regalado;Frank Bernardoni

  • A CHIRAL RECOGNITION MODEL FOR THE CHROMATOGRAPHIC RESOLUTION OF N‐ACYLATED 1‐ARYL‐1‐AMINOALKANES

    William H. Pirkle;Christopher J. Welch;Myung Ho Hyun

  • Do the short helices exist in the nematic TB phase

    Ewa Górecka;Mirosław Salamończyk;Anna Zep;Damian Pociecha

  • New chiral crown ether stationary phase for the liquid chromatographic resolution of α-amino acid enantiomers

    Myung Ho Hyun;Sang Cheol Han;Bruce H. Lipshutz;Young-Jun Shin

Frequent Co-Authors

Georg H. Mehl
Georg H. Mehl University of Hull
William H. Pirkle
William H. Pirkle University of Illinois at Urbana-Champaign
Antal Jakli
Antal Jakli Kent State University
Oleg D. Lavrentovich
Oleg D. Lavrentovich Kent State University
Jyoti Chattopadhyaya
Jyoti Chattopadhyaya Uppsala University
Stephen M. Morris
Stephen M. Morris University of Oxford
Timothy D. Wilkinson
Timothy D. Wilkinson University of Cambridge
Goran Ungar
Goran Ungar Xi'an Jiaotong University
Ian W. Davies
Ian W. Davies Princeton University
Daniel W. Armstrong
Daniel W. Armstrong The University of Texas at Arlington

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