World's Best Scientists 2026 revealed!

D-Index & Metrics

Engineering and Technology

D-Index
74
Citations
30364
World Ranking
789
National Ranking
271

Overview

Charles E. Metz was affiliated with the University of Chicago in the United States. Their research contributed to the field of medicine, focusing on several specialized subfields including rheumatology, physiology, health toxicology and mutagenesis, general health professions, and health.

Their scientific work addressed a range of topics with multiple publications focusing on lysosomal storage disorders research. Additional areas of study included climate change and health impacts, homelessness and social issues, health disparities and outcomes, cardiovascular health and risk factors, advanced statistical process monitoring, and business process modeling and analysis.

Notable recent publications by Charles E. Metz included the following:

  • Heat-Related Health Risks for People Experiencing Homelessness: A Rapid Review (2025, Journal of Urban Health)
  • Abstract 4144863: Impact of Phone Outreach and In-Person Education on Blood Pressure Control in Black Patients with Severe Hypertension at a Federally Qualified Health Center (FQHC) (2024, Circulation)
  • Statistical Process Control Charts to Improve Health Care: Hypertension Case (2025, AACN Advanced Critical Care)
  • Local immunoglobulin expression in myositis is associated with interferon gamma signaling and correlates with disease activity (2025, bioRxiv (Cold Spring Harbor Laboratory))
  • Molecular modulation in Pompe disease following acute intermittent hypoxia (2025, Physiology)

Throughout their career, they frequently collaborated with several coauthors, including:

  • Camryn Johnson
  • Anna Tharakan
  • Elliot Yoon
  • Bradi B. Granger
  • Angela L. Roger

The venues where Metz published often included:

  • Journal of Urban Health
  • Circulation
  • AACN Advanced Critical Care
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Physiology

Best Publications

  • Basic principles of ROC analysis

    Charles E. Metz

  • ROC methodology in radiologic imaging

    Charles E. Metz

  • Some practical issues of experimental design and data analysis in radiological ROC studies.

    Charles E. Metz

  • Maximum likelihood estimation of receiver operating characteristic (ROC) curves from continuously-distributed data

    Charles E. Metz;Benjamin A. Herman;Jong-Her Shen

  • Receiver operating characteristic rating analysis. Generalization to the population of readers and patients with the jackknife method.

    Donald D. Dorfman;Kevin S. Berbaum;Charles E. Metz

  • Artificial neural networks in mammography: application to decision making in the diagnosis of breast cancer.

    Yuzheng Wu;M. L. Giger;Kunio Doi;C. J. Vyborny

  • Improvement in radiologists' detection of clustered microcalcifications on mammograms. The potential of computer-aided diagnosis.

    H P Chan;K Doi;C J Vyborny;R A Schmidt

  • A New Approach for Testing the Significance of Differences Between ROC Curves Measured from Correlated Data

    Charles E. Metz;Pu-Lan Wang;Helen B. Kronman

  • Statistical Comparison of Two ROC-curve Estimates Obtained from Partially-paired Datasets

    Charles E. Metz;Benjamin A. Herman;Cheryl A. Roe

  • The exponential Radon transform

    Oleh Tretiak;Charles Metz

  • Improving breast cancer diagnosis with computer-aided diagnosis

    Yulei Jiang;Robert M. Nishikawa;Robert A. Schmidt;Charles E. Metz

  • Receiver operating characteristic analysis: a tool for the quantitative evaluation of observer performance and imaging systems.

    Charles E. Metz

  • A receiver operating characteristic partial area index for highly sensitive diagnostic tests

    Y Jiang;C E Metz;R M Nishikawa

  • ”Proper” binormal ROC curves: theory and maximum-likelihood estimation

    Charles E. Metz;Xiaochuan Pan

  • Malignant and benign clustered microcalcifications: automated feature analysis and classification.

    Y Jiang;R M Nishikawa;D E Wolverton;C E Metz

  • Computerized detection of masses in digital mammograms: analysis of bilateral subtraction images.

    Fang-Fang Yin;Maryellen L. Giger;Kunio Doi;Charles E. Metz

  • Effect of a computer-aided diagnosis scheme on radiologists' performance in detection of lung nodules on radiographs.

    T Kobayashi;X W Xu;H MacMahon;C E Metz

  • Visual detection and localization of radiographic images.

    Stuart J. Starr;Charles E. Metz;Lee B. Lusted;David J. Goodenough

  • Digital Mammography: ROC Studies of the Effects of Pixel Size and Unsharp-Mask Filtering on the Detection of Subtle Microcalcifications

    Heang Ping Chan;Carl J. Vyborny;Heber MacMahon;Charles E. Metz

  • Statistical significance tests for binormal ROC curves

    Charles E Metz;Helen B Kronman

Frequent Co-Authors

Kunio Doi
Kunio Doi University of Chicago
Maryellen L. Giger
Maryellen L. Giger University of Chicago
Robert M. Nishikawa
Robert M. Nishikawa University of Pittsburgh
Heang Ping Chan
Heang Ping Chan University of Michigan–Ann Arbor
Heber MacMahon
Heber MacMahon University of Chicago
Stephen M. Pizer
Stephen M. Pizer University of North Carolina at Chapel Hill
Xiaochuan Pan
Xiaochuan Pan University of Chicago
Benjamin M. W. Tsui
Benjamin M. W. Tsui Johns Hopkins University
Xiaoping Hu
Xiaoping Hu University of California, Riverside
Wing Hung Wong
Wing Hung Wong Stanford University

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