2026 Charles A. Specht: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	64	9878	9117	4327	3886	121	11720

Overview

Charles A. Specht is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily lies within the field of Medicine, with a focus on subfields such as Epidemiology, Infectious Diseases, Molecular Biology, Neurology, and Immunology.

The main topics covered in Charles A. Specht's work include:

Fungal Infections and Studies
Antifungal resistance and susceptibility
Nail Diseases and Treatments
Plant-Microbe Interactions and Immunity
Full-Duplex Wireless Communications
Asthma and respiratory diseases
RNA and protein synthesis mechanisms

Recent publications give an overview of the areas of their research:

Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression, 2020, Nature Communications
Vaccines for human fungal diseases: close but still a long way to go, 2021, npj Vaccines
Cryptococcus neoformans Cda1 and Cda2 coordinate deacetylation of chitin during infection to control fungal virulence, 2021, The Cell Surface
Protection of Mice against Experimental Cryptococcosis by Synthesized Peptides Delivered in Glucan Particles, 2022, mBio
Immunological correlates of protection following vaccination with glucan particles containing Cryptococcus neoformans chitin deacetylases, 2023, npj Vaccines

Frequent co-authors collaborating with Charles A. Specht include:

Stuart M. Levitz
Lorena V. N. Oliveira
Chrono K. Lee
Maureen M. Hester
Ruiying Wang

Publications are often found in specific venues, indicating established connections with certain journals and audiences. Notable publication venues are:

Laryngo-Rhino-Otologie
bioRxiv (Cold Spring Harbor Laboratory)
mBio
PLoS Pathogens
World Neurosurgery

Best Publications

The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus Neoformans

Brendan J. Loftus;Eula Fung;Paola Roncaglia;Don Rowley

882
Citations
Chitosan, the Deacetylated Form of Chitin, Is Necessary for Cell Wall Integrity in Cryptococcus neoformans

Lorina G. Baker;Charles A. Specht;Maureen J. Donlin;Jennifer K. Lodge

430
Citations
The Tribolium chitin synthase genes TcCHS1 and TcCHS2 are specialized for synthesis of epidermal cuticle and midgut peritrophic matrix.

Y. Arakane;S. Muthukrishnan;K. J. Kramer;K. J. Kramer;C. A. Specht

364
Citations
A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans.

Isaac R. Banks;Charles A. Specht;Maureen J. Donlin;Kimberly J. Gerik

274
Citations
Chitosan but Not Chitin Activates the Inflammasome by a Mechanism Dependent upon Phagocytosis

Chelsea L. Bueter;Chrono K. Lee;Vijay A.K. Rathinam;Gloria J. Healy

248
Citations
A method for extracting high-molecular-weight deoxyribonucleic acid from fungi.

Charles A. Specht;Concetta C. DiRusso;Charles P. Novotny;Robert C. Ullrich

248
Citations
Innate sensing of chitin and chitosan

Chelsea L. Bueter;Charles A. Specht;Stuart M. Levitz

238
Citations
Chitin synthases are required for survival, fecundity and egg hatch in the red flour beetle, Tribolium castaneum.

Yasuyuki Arakane;Charles A. Specht;Karl J. Kramer;Karl J. Kramer;Subbaratnam Muthukrishnan

221
Citations
Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.

Darin L. Wiesner;Charles A. Specht;Chrono K. Lee;Kyle D. Smith

220
Citations
Characterization of two chitin synthase genes of the red flour beetle, Tribolium castaneum, and alternate exon usage in one of the genes during development.

Yasuyuki Arakane;David G. Hogenkamp;Yu Cheng Zhu;Karl J. Kramer;Karl J. Kramer

216
Citations
Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA.

Zaida G. Ramirez-Ortiz;Charles A. Specht;Jennifer P. Wang;Chrono K. Lee

210
Citations
The molecular basis for the immunogenicity of Cryptococcus neoformans mannoproteins

Stuart M. Levitz;Charles A. Specht

203
Citations
Chitin synthesis in Saccharomyces cerevisiae in response to supplementation of growth medium with glucosamine and cell wall stress.

Dorota A. Bulik;Mariusz Olczak;Hector A. Lucero;Barbara C. Osmond

197
Citations
Domain organization and phylogenetic analysis of proteins from the chitin deacetylase gene family of Tribolium castaneum and three other species of insects.

Radhika Dixit;Yasuyuki Arakane;Charles A. Specht;Chad Richard

194
Citations
Recognition of Aspergillus fumigatus Hyphae by Human Plasmacytoid Dendritic Cells Is Mediated by Dectin-2 and Results in Formation of Extracellular Traps

Flávio V. Loures;Marc Röhm;Chrono K. Lee;Evelyn Santos

192
Citations
Distinct Patterns of Dendritic Cell Cytokine Release Stimulated by Fungal β-Glucans and Toll-Like Receptor Agonists

Haibin Huang;Gary R. Ostroff;Chrono K. Lee;Jennifer P. Wang

192
Citations
Analysis of functions of the chitin deacetylase gene family in Tribolium castaneum

Yasuyuki Arakane;Radhika Dixit;Khurshida Begum;Yoonseong Park

187
Citations
Robust stimulation of humoral and cellular immune responses following vaccination with antigen-loaded beta-glucan particles.

Haibin Huang;Gary R. Ostroff;Chrono K. Lee;Charles A. Specht

185
Citations
Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T cell responses to Cryptococcus neoformans

Stuart M. Levitz;Shu-hua Nong;Michael K. Mansour;Chao Huang

170
Citations
The A alpha mating locus of Schizophyllum commune encodes two dissimilar multiallelic homeodomain proteins

Mary M. Stankis;Charles A. Specht;Huiling Yang;Luc Giasson

169
Citations