Ben Youngblood

Best Publications

• Defining ‘T cell exhaustion’

  Christian U Blank;W Nicholas Haining;Werner Held;Patrick G Hogan;Patrick G Hogan

  1487
  Citations

• TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.

  Francesca Alfei;Kristiyan Kanev;Maike Hofmann;Ming Wu

  849
  Citations

• De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation

  Hazem E. Ghoneim;Yiping Fan;Ardiana Moustaki;Hossam A. Abdelsamed

  785
  Citations

• Origin and differentiation of human memory CD8 T cells after vaccination

  Rama Akondy;Mark Fitch;Srilatha Edupuganti;Shu Yang

  549
  Citations

• Effector CD8 T cells dedifferentiate into long-lived memory cells

  Ben Youngblood;Ben Youngblood;J. Scott Hale;Haydn Thomas Kissick;Eunseon Ahn

  486
  Citations

• Chronic Virus Infection Enforces Demethylation of the Locus that Encodes PD-1 in Antigen-Specific CD8+ T Cells

  Benjamin Alan Youngblood;Kenneth J. Oestreich;Kenneth J. Oestreich;Sang-Jun Ha;Sang-Jun Ha;Jaikumar Duraiswamy

  458
  Citations

• Impact of the COVID-19 nonpharmaceutical interventions on influenza and other respiratory viral infections in New Zealand.

  Q Sue Huang;Tim Wood;Lauren Jelley;Tineke Jennings

  457
  Citations

• Distinct Memory CD4+ T Cells with Commitment to T Follicular Helper- and T Helper 1-Cell Lineages Are Generated after Acute Viral Infection

  J. Scott Hale;Ben Youngblood;Donald R. Latner;Ata Ur Rasheed Mohammed

  381
  Citations

• mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.

  Hu Zeng;Sivan Cohen;Cliff Guy;Sharad Shrestha

  350
  Citations

• PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells

  Erin E. West;Hyun Tak Jin;Ata Ur Rasheed;Pablo Penaloza-MacMaster;Pablo Penaloza-MacMaster

  349
  Citations

• Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans.

  Giovanni Galletti;Gabriele De Simone;Emilia M C Mazza;Simone Puccio

  304
  Citations

• Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity.

  Brooke Prinzing;Caitlin C. Zebley;Christopher T. Petersen;Yiping Fan

  304
  Citations

• Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1.

  Ewelina Mamcarz;Sheng Zhou;Timothy Lockey;Hossam Abdelsamed

  279
  Citations

• Developmental plasticity allows outside-in immune responses by resident memory T cells.

  Raissa Fonseca;Raissa Fonseca;Lalit K Beura;Lalit K Beura;Clare F Quarnstrom;Hazem E Ghoneim;Hazem E Ghoneim

  267
  Citations

• The role of mTOR in memory CD8 T-cell differentiation.

  Koichi Araki;Benjamin Alan Youngblood;Rafi Ahmed

  222
  Citations

• Global DNA Methylation Remodeling Accompanies CD8 T Cell Effector Function

  Christopher D. Scharer;Benjamin G. Barwick;Benjamin A. Youngblood;Rafi Ahmed

  217
  Citations

• PI3K orchestration of the in vivo persistence of chimeric antigen receptor-modified T cells.

  Wenting Zheng;Carol E. O’Hear;Carol E. O’Hear;Rajshekhar Alli;Jacob H. Basham

  202
  Citations

• SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans

  E Kaitlynn Allen;Adrienne G Randolph;Tushar Bhangale;Pranay Dogra

  190
  Citations

• T-cell memory differentiation: insights from transcriptional signatures and epigenetics.

  Ben Youngblood;J. Scott Hale;Rafi Ahmed

  186
  Citations

• Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells.

  Benjamin Youngblood;Alessandra Noto;Filippos Porichis;Rama Akondy

  179
  Citations