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Chemistry

D-Index
78
Citations
16634
World Ranking
3909
National Ranking
290

Research.com Recognitions

  • 2016 - Fellow of the American Psychological Association (APA)

Overview

Alfred Blume is affiliated with Martin Luther University Halle-Wittenberg in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, with particular emphasis on molecular biology as well as the study of surfaces, coatings, and films. Their work also intersects with biomedical engineering, materials chemistry, and imaging techniques related to radiology and nuclear medicine.

The scientist's recent publications cover several themes around lipid membrane structure and behavior, protein purification and stability, polymer surface interactions, RNA interference and gene delivery, viral infectious diseases and gene expression in insects, and antibody research including monoclonal and polyclonal antibodies. The main topics of their research include:

  • Lipid Membrane Structure and Behavior
  • Protein Purification and Stability
  • Polymer Surface Interaction Studies
  • RNA Interference and Gene Delivery
  • Viral Infectious Diseases and Gene Expression in Insects
  • Monoclonal and Polyclonal Antibodies Research
  • Protein Interaction Studies and Fluorescence Analysis

Recent published papers by Alfred Blume demonstrate an interest in biophysical and biochemical properties related to lipid membranes and surfactants. Selected works include:

  • Surface Tension and Self-association Properties of Aqueous Polysorbate 20 HP and 80 HP Solutions: Insights into Protein Stabilisation Mechanisms, 2020, Journal of Pharmaceutical Innovation
  • Albumin Displacement at the Air-Water Interface by Tween (Polysorbate) Surfactants, 2020, European Biophysics Journal
  • Ligand Distribution and Lipid Phase Behavior in Phospholipid-Coated Microbubbles and Monolayers, 2020, Langmuir
  • Filling the Gap with Long n-Alkanes: Incorporation of C20 and C30 into Phospholipid Membranes, 2022, Langmuir
  • Monolayer Behavior of Pure F-DPPC and Mixed Films with DPPC Studied by Epifluorescence Microscopy and Infrared Reflection Absorption Spectroscopy, 2020, Chemistry and Physics of Lipids

Alfred Blume frequently collaborates with other researchers. Notable co-authors include:

  • Patrick Garidel
  • Andreas Kerth
  • Christian Schwieger
  • Michaela Blech
  • Julia Buske

The main publication venues where Blume has contributed include:

  • Langmuir
  • Journal of Pharmaceutical Innovation
  • European Biophysics Journal
  • European Journal of Pharmaceutical Sciences
  • Biochimica et Biophysica Acta (BBA) - Biomembranes

In recognition of professional contributions, Alfred Blume was awarded the title of Fellow of the American Psychological Association (APA) in 2016.

Best Publications

  • Fourier transform infrared spectroscopy of 13C = O-labeled phospholipids hydrogen bonding to carbonyl groups.

    A Blume;W Hübner;G Messner

  • A comparative study of the phase transitions of phospholipid bilayers and monolayers

    Alfred Blume

  • Thermodynamics of Micelle Formation as a Function of Temperature - A High-Sensitivity Titration Calorimetry Study

    Stefan Paula;Willy Sues;Juergen Tuchtenhagen;Alfred Blume

  • Phospholipids and lipid-based formulations in oral drug delivery.

    Gert Fricker;Torsten Kromp;Armin Wendel;Alfred Blume

  • Regulation of Acetylcholinesterase in Neuroblastoma Cells

    Arthur J. Blume;F. Gilbert;S. Wilson;John L. Farber

  • Interactions at the lipid–water interface

    Wigand Hübner;Alfred Blume

  • Thermodynamic Characterization of Bile Salt Aggregation as a Function of Temperature and Ionic Strength Using Isothermal Titration Calorimetry

    P. Garidel;A. Hildebrand;and R. Neubert;A. Blume

  • Apparent molar heat capacities of phospholipids in aqueous dispersion. Effects of chain length and head group structure

    Alfred Blume

  • A comparative study of diffusive and osmotic water permeation across bilayers composed of phospholipids with different head groups and fatty acyl chains

    M. Jansen;A. Blume

  • A 13C and 2H nuclear magnetic resonance study of phosphatidylcholine/cholesterol interactions: characterization of liquid-gel phases.

    T. H. Huang;C. W. B. Lee;S. K. Das Gupta;A. Blume

  • Mechanism of Islet Amyloid Polypeptide Fibrillation at Lipid Interfaces Studied by Infrared Reflection Absorption Spectroscopy

    D.H.J. Lopes;A. Meister;A. Gohlke;A. Hauser

  • Calamitic Bolaamphiphiles with (Semi)Perfluorinated Lateral Chains: Polyphilic Block Molecules with New Liquid Crystalline Phase Structures

    Xiaohong Cheng;Marko Prehm;Malay Kumar Das;Jens Kain

  • Hsp12 Is an Intrinsically Unstructured Stress Protein that Folds upon Membrane Association and Modulates Membrane Function

    Sylvia Welker;Birgit Rudolph;Elke Frenzel;Franz Hagn

  • Peptide induced demixing in PG/PE lipid mixtures: A mechanism for the specificity of antimicrobial peptides towards bacterial membranes?

    Ahmad Arouri;Margitta Dathe;Alfred Blume

  • Thermodynamic Characterization of Temperature-Induced Micellization and Demicellization of Detergents Studied by Differential Scanning Calorimetry

    Pinaki R. Majhi and;Alfred Blume

  • A critical assessment of micellization of sodium dodecyl benzene sulfonate (SDBS) and its interaction with poly(vinyl pyrrolidone) and hydrophobically modified polymers, JR 400 and LM 200

    Unknown

  • Phase behaviour and crystallinity of plant cuticular waxes studied by Fourier transform infrared spectroscopy

    Susanne Merk;Alfred Blume;Markus Riederer

  • The influence of charge on phosphatidic acid bilayer membranes.

    Hansjörg Eibl;Alfred Blume

  • Thermotropic lipid clustering in tetrahymena membranes

    Frank Wunderlich;Adam Ronai;Volker Speth;Joachim Seelig

  • Membranolytic activity of bile salts: influence of biological membrane properties and composition.

    Patrick Garidel;Annegret Hildebrand;Katja Knauf;Alfred Blume

  • RÖMPP Lexikon Chemie

    Jürgen Falbe;Manfred Regitz;Eckard Amelingmeier;Michael Berger

  • A Fourier transform infrared spectroscopic study of the interaction of alkaline earth cations with the negatively charged phospholipid 1, 2-dimyristoyl-sn-glycero-3-phosphoglycerol.

    Patrick Garidel;Alfred Blume;Wigand Hübner

Frequent Co-Authors

Jörg Kressler
Jörg Kressler Martin Luther University Halle-Wittenberg
Gerd Hause
Gerd Hause Martin Luther University Halle-Wittenberg
Heiko Heerklotz
Heiko Heerklotz University of Freiburg
Carsten Tschierske
Carsten Tschierske Martin Luther University Halle-Wittenberg
Vasil M. Garamus
Vasil M. Garamus Helmholtz-Zentrum Geesthacht Centre for Materials and Coastal Research
Kay Saalwächter
Kay Saalwächter Martin Luther University Halle-Wittenberg
Markus Drechsler
Markus Drechsler University of Bayreuth
Roland Winter
Roland Winter TU Dortmund University
Klaus Brandenburg
Klaus Brandenburg Leibniz Institute for Neurobiology

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