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Neuroscience

D-Index
62
Citations
16356
World Ranking
3488
National Ranking
128

Overview

Alfonso Represa is affiliated with Aix-Marseille University in France and specializes in research intersecting biochemistry, genetics, molecular biology, medicine, and neuroscience. Their work spans several subfields including molecular biology, genetics, cellular and molecular neuroscience, pediatrics, perinatology, child health, psychiatry, and mental health.

Their main research topics encompass:

  • Fetal and Pediatric Neurological Disorders
  • Epilepsy research and treatment
  • Genetics and Neurodevelopmental Disorders
  • Tuberous Sclerosis Complex Research
  • Cerebrospinal fluid and hydrocephalus
  • Neuroscience and Neuropharmacology Research
  • RNA Research and Splicing

Alfonso Represa has published in several scientific venues, frequently contributing to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Psychiatry
  • Epilepsia
  • Neurobiology of Disease
  • Frontiers in Neuroscience

Frequent collaborators in their research include Carlos Cardoso, Françoise Watrin, A. Gélot, Antoine de Chevigny, and Emmanuelle Buhler.

Recent scientific papers include:

  • Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons, 2021, Molecular Psychiatry
  • Progression of Fetal Brain Lesions in Tuberous Sclerosis Complex, 2020, Frontiers in Neuroscience
  • A recurrent de novo splice site variant involving DNM1 exon 10a causes developmental and epileptic encephalopathy through a dominant-negative mechanism, 2022, The American Journal of Human Genetics
  • Grey matter heterotopia subtypes show specific morpho-electric signatures and network dynamics, 2023, Brain
  • Pathogenic MTOR somatic variant causing focal cortical dysplasia drives hyperexcitability via overactivation of neuronal GluN2C N-methyl-D-aspartate receptors, 2024, Epilepsia

Best Publications

  • The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission

    Ingmar Blümcke;Maria Thom;Eleonora Aronica;Dawna D. Armstrong

  • GABAergic Hub Neurons Orchestrate Synchrony in Developing Hippocampal Networks

    Paolo Bonifazi;Miri Goldin;Michel Picardo;Isabel Jorquera

  • Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis.

    C Charriaut-Marlangue;I Margaill;A Represa;T Popovici

  • Maternal oxytocin triggers a transient inhibitory switch in GABA signaling in the fetal brain during delivery.

    Roman Tyzio;Rosa Cossart;Ilgam Khalilov;Marat Minlebaev

  • Trophic actions of GABA on neuronal development

    Alfonso Represa;Yehezkel Ben-Ari

  • Kainate-induced apoptotic cell death in hippocampal neurons

    H. Pollard;C. Charriaut-Marlangue;S. Cantagrel;A. Represa

  • Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus.

    Yehezkel Ben-Ari;Alfonso Represa

  • NCAM Is Essential for Axonal Growth and Fasciculation in the Hippocampus

    Harold Cremer;Genèvieve Chazal;Christo Goridis;Alfonso Represa

  • Mutations in the [beta]-tubulin gene TUBB2B result in asymmetrical polymicrogyria

    Xavier Hubert Jaglin;Karine Poirier;Karine Poirier;Yoann Saillour;Yoann Saillour;Emmanuelle Buhler

  • Kainate binding sites in the hippocampal mossy fibers: Localization and plasticity

    A. Represa;A. Represa;E. Tremblay;E. Tremblay;Y. Ben-Ari;Y. Ben-Ari

  • The Establishment of GABAergic and Glutamatergic Synapses on CA1 Pyramidal Neurons is Sequential and Correlates with the Development of the Apical Dendrite

    Roman Tyzio;Alfonso Represa;Isabel Jorquera;Yehezkel Ben-Ari

  • Paracrine intercellular communication by a Ca2+- and SNARE-independent release of GABA and glutamate prior to synapse formation.

    Michael Demarque;Alfonso Represa;Hélène Becq;Ilgam Khalilov

  • Transient increased density of NMDA binding sites in the developing rat hippocampus

    Evelyne Tremblay;Marie Paule Roisin;Alfonso Represa;Christiane Charriaut-Marlangue

  • Neurogranin: immunocytochemical localization of a brain-specific protein kinase C substrate

    A. Represa;J. C. Deloulme;M. Sensenbrenner;Yehezkel Ben-Ari

  • A Noncanonical Release of GABA and Glutamate Modulates Neuronal Migration

    Jean-Bernard Manent;Michaël Demarque;Isabel Jorquera;Christophe Pellegrino

  • Hippocampal plasticity in the kindling model of epilepsy in rats.

    Alfonso Represa;Yehezkel Ben-Ari

  • Atlas of the Postnatal Rat Brain in Stereotaxic Coordinates

    Roustem Khazipov;Dilyara Zaynutdinova;Elena Ogievetsky;Elena Ogievetsky;Guzel Valeeva

  • Apoptotic features of selective neuronal death in ischemia, epilepsy and gpI20 toxicity

    C. Charriaut-Marlangue;D. Aggoun-Zouaoui;A. Represa;Y. Ben-Ari

  • Epilepsy induced collateral sprouting of hippocampal mossy fibers: does it induce the development of ectopic synapses with granule cell dendrites?

    Alfonso Represa;Isabel Jorquera;Yehezkel Ben-Ari

  • Effects of kainic acid-induced seizures and ischemia on c-fos-like proteins in rat brain.

    Theodora Popovici;Alfonso Represa;Vale´rie Cre´pel;Gilles Barbin

Frequent Co-Authors

Yehezkel Ben-Ari
Yehezkel Ben-Ari Neurochlore (France)
Christiane Charriaut-Marlangue
Christiane Charriaut-Marlangue Université Paris Cité
Ilgam Khalilov
Ilgam Khalilov Inserm : Institut national de la santé et de la recherche médicale
Harold Cremer
Harold Cremer Aix-Marseille University
Renzo Guerrini
Renzo Guerrini University of Florence
Sylvain Rheims
Sylvain Rheims Claude Bernard University Lyon 1
Pietro Baldelli
Pietro Baldelli University of Genoa
Albert J. Becker
Albert J. Becker University Hospital Bonn
Mathieu Milh
Mathieu Milh Aix-Marseille University
Yuri Zilberter
Yuri Zilberter Aix-Marseille University

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