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Biology and Biochemistry

D-Index
52
Citations
14318
World Ranking
16494
National Ranking
6828

Overview

Aalim M. Weljie is affiliated with the University of Pennsylvania in the United States. Their research spans multiple fields including Biochemistry, Genetics and Molecular Biology, Neuroscience, and Medicine. The work notably integrates subfields such as Molecular Biology, Endocrine and Autonomic Systems, Immunology, Physiology, and Cellular and Molecular Neuroscience.

Their research topics cover a range of areas, with particular focus on Circadian rhythm and melatonin, Metabolomics and Mass Spectrometry Studies, Sleep and Wakefulness Research, Neurobiology and Insect Physiology Research, Sleep and related disorders, Immune cells in cancer, and Cancer, Hypoxia, and Metabolism.

Weljie has published frequently in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cell Metabolism
  • SLEEP
  • Cancer Research

Recent publications by Weljie highlight various aspects of cellular metabolism, cancer biology, and circadian regulation. Selected papers include:

  • "A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression," 2022, Nature Cell Biology
  • "Targeting glutamine metabolism slows soft tissue sarcoma growth," 2020, Nature Communications
  • "PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy," 2023, Cell Metabolism
  • "Mitochondrial dysfunction in inflammatory bowel disease alters intestinal epithelial metabolism of hepatic acylcarnitines," 2020, Journal of Clinical Investigation
  • "Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells," 2021, Nature Communications

Weljie frequently collaborates with other researchers. Notable co-authors include:

  • Arjun Sengupta
  • Dania Malik
  • Garret A. FitzGerald
  • Amita Sehgal
  • Serge Y. Fuchs

Best Publications

  • HMDB: The human metabolome database

    David S. Wishart;Dan Tzur;Craig Knox;Roman Eisner

  • A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance

    Cholsoon Jang;Sungwhan F Oh;Shogo Wada;Glenn C Rowe

  • Comparative metabolomics in vegans and omnivores reveal constraints on diet-dependent gut microbiota metabolite production

    Gary D Wu;Charlene Compher;Eric Z Chen;Sarah A Smith

  • Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles.

    Carolyn M. Slupsky;Kathryn N. Rankin;James Wagner;Hao Fu

  • ATP-citrate lyase controls a glucose-to-acetate metabolic switch

    Steven Zhao;AnnMarie Torres;Ryan A. Henry;Sophie Trefely

  • MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells

    Brian J. Altman;Annie L. Hsieh;Annie L. Hsieh;Arjun Sengupta;Saikumari Y. Krishnanaiah

  • Candida albicans stimulates Streptococcus mutans microcolony development via cross-kingdom biofilm-derived metabolites.

    Dongyeop Kim;Arjun Sengupta;Tagbo H. R. Niepa;Byung-Hoo Lee

  • Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination

    Sharanya Sivanand;Seth Rhoades;Qinqin Jiang;Joyce V. Lee

  • Differences in metabolism between the biofilm and planktonic response to metal stress.

    Sean C. Booth;Matthew L. Workentine;Jing Wen;Rustem Shaykhutdinov

  • Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism

    Saikumari Y. Krishnaiah;Gang Wu;Gang Wu;Brian J. Altman;Jacqueline Growe

  • An in vivo patient-derived model of endogenous IDH1-mutant glioma

    H. Artee Luchman;Owen D. Stechishin;N. Ha Dang;Michael D. Blough

  • Feasibility of Identifying Pancreatic Cancer based on Serum Metabolomics

    Oliver F Bathe;Rustem Shaykhutdinov;Karen Kopciuk;Aalim M Weljie

  • Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt

    Aalim M. Weljie;Peter Meerlo;Namni Goel;Arjun Sengupta

  • An inflammatory arthritis-associated metabolite biomarker pattern revealed by 1H NMR spectroscopy.

    Aalim M Weljie;Reza Dowlatabadi;B Joan Miller;Hans J Vogel

  • Hypoxia-induced metabolic shifts in cancer cells: Moving beyond the Warburg effect

    Aalim M. Weljie;Frank R. Jirik

  • Metabolomic profiling of dietary-induced insulin resistance in the high fat-fed C57BL/6J mouse.

    J. Shearer;G. Duggan;A. Weljie;D. S. Hittel

  • Quality Assessment of Ginseng by 1H NMR Metabolite Fingerprinting and Profiling Analysis

    Eun-Jeong Lee;Rustem Shaykhutdinov;Aalim M. Weljie;Hans J. Vogel

  • A validated metabolomic signature for colorectal cancer: exploration of the clinical value of metabolomics

    Farshad Farshidfar;Aalim M Weljie;Aalim M Weljie;Karen A Kopciuk;Karen A Kopciuk;Robert Hilsden;Robert Hilsden

  • Serum metabolomic profile as a means to distinguish stage of colorectal cancer

    Farshad Farshidfar;Aalim M Weljie;Karen Kopciuk;W Don Buie

  • The Solution Structure of the C-terminal Domain of TonB and Interaction Studies with TonB Box Peptides

    R. Sean Peacock;Aalim M. Weljie;S. Peter Howard;Feodor D. Price

Frequent Co-Authors

Raymond J. Turner
Raymond J. Turner University of Calgary
Amita Sehgal
Amita Sehgal University of Pennsylvania
John B. Hogenesch
John B. Hogenesch Cincinnati Children's Hospital Medical Center
Michael J. Bennett
Michael J. Bennett University Hospital Southampton NHS Foundation Trust
Joseph A. Baur
Joseph A. Baur University of Pennsylvania
Derek C. Angus
Derek C. Angus University of Pittsburgh
Chi V. Dang
Chi V. Dang University of Pennsylvania
Peter J. Facchini
Peter J. Facchini University of Calgary
Howard Ceri
Howard Ceri University of Calgary
Frederic D. Bushman
Frederic D. Bushman University of Pennsylvania

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