World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
12821
World Ranking
11387
National Ranking
871

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Antibody
  • Cytokine

His main research concerns Trophoblast, Decidua, Natural killer cell, Molecular biology and Immunology. His work deals with themes such as Human leukocyte antigen, Antigen and Choriocarcinoma, which intersect with Trophoblast. His Decidua research integrates issues from Interleukin 21, Internal medicine and Endocrinology.

As a part of the same scientific study, he usually deals with the Natural killer cell, concentrating on Cytokine and frequently concerns with Lymphocyte, Growth factor receptor, Umbilical vein and Growth factor. Yung Wai Loke has researched Immunology in several fields, including Extracellular matrix and Cell biology. His research investigates the connection with Cell biology and areas like K562 cells which intersect with concerns in Decidual cells and Cytotoxicity.

His most cited work include:

  • HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells. (322 citations)
  • Immunocytochemical characterization of the unusual large granular lymphocytes in human endometrium throughout the menstrual cycle. (267 citations)
  • Angiogenic growth factor messenger ribonucleic acids in uterine natural killer cells. (265 citations)

What are the main themes of his work throughout his whole career to date?

Trophoblast, Cell biology, Decidua, Immunology and Molecular biology are his primary areas of study. His biological study spans a wide range of topics, including Cytotrophoblast, Monoclonal antibody and Antigen. His Cell biology research is multidisciplinary, relying on both In vitro, Neural cell adhesion molecule and Cytokine.

His studies in Decidua integrate themes in fields like Stromal cell, Internal medicine, Endocrinology, Natural killer cell and Interleukin 21. Yung Wai Loke interconnects Fetus, Receptor and Placentation in the investigation of issues within Immunology. Yung Wai Loke has included themes like Immunocytochemistry and Choriocarcinoma in his Molecular biology study.

He most often published in these fields:

  • Trophoblast (61.61%)
  • Cell biology (41.07%)
  • Decidua (40.18%)

What were the highlights of his more recent work (between 1997-2020)?

  • Immunology (38.39%)
  • Natural killer cell (19.64%)
  • Trophoblast (61.61%)

In recent papers he was focusing on the following fields of study:

Yung Wai Loke focuses on Immunology, Natural killer cell, Trophoblast, Decidua and Human leukocyte antigen. In Immunology, Yung Wai Loke works on issues like Cancer research, which are connected to Interferon, CTL*, Immunofluorescence and Cytotoxic T cell. His study on NK-92 is often connected to Reproduction as part of broader study in Natural killer cell.

The study incorporates disciplines such as Molecular biology and Placentation in addition to Trophoblast. His research integrates issues of Interleukin 21, Internal medicine, Endocrinology and Cell biology in his study of Decidua. His study in the fields of HLA-G under the domain of Human leukocyte antigen overlaps with other disciplines such as Class.

Between 1997 and 2020, his most popular works were:

  • HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells. (322 citations)
  • Angiogenic growth factor messenger ribonucleic acids in uterine natural killer cells. (265 citations)
  • Human Decidual Natural Killer Cells Express the Receptor for and Respond to the Cytokine Interleukin 15 (231 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Antibody
  • Cytokine

His primary areas of study are Trophoblast, Natural killer cell, Decidua, Molecular biology and Human leukocyte antigen. His study with Trophoblast involves better knowledge in Fetus. His Natural killer cell study incorporates themes from Angiogenesis, Interleukin 21, Immunology, MHC class I and Cell biology.

The Decidua study combines topics in areas such as Blood vessel, Artery, Endocrinology, Uterus and Internal medicine. His Molecular biology research includes elements of HLA-G and Embryo. His Human leukocyte antigen study combines topics in areas such as Beta-2 microglobulin and Interferon gamma.

Best Publications

  • HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells.

    Ashley King;David S. J. Allan;Mark Bowen;Simon J. Powis

  • Immunocytochemical characterization of the unusual large granular lymphocytes in human endometrium throughout the menstrual cycle.

    Ashley King;Vanessa Wellings;Lucy Gardner;Y.W. Loke

  • Angiogenic growth factor messenger ribonucleic acids in uterine natural killer cells.

    Xiao Feng Li;D. Stephen Charnock-Jones;Eko Zhang;Susan Hiby

  • CD3- leukocytes present in the human uterus during early placentation: phenotypic and morphologic characterization of the CD56++ population.

    Ashley King;Nalini Balendran;P. Wooding;N. P. Carter

  • Human Decidual Natural Killer Cells Express the Receptor for and Respond to the Cytokine Interleukin 15

    Sanjay Verma;Susan E. Hiby;Yung Wai Loke;Ashley King

  • On the nature and function of human uterine granular lymphocytes.

    Ashley King;Yung Wai Loke

  • Human implantation : cell biology and immunology

    Y. W. Loke;Ashley King

  • Surface expression of HLA-C antigen by human extravillous trophoblast

    A. King;T.D. Burrows;S.E. Hiby;J.M. Bowen

  • The role of trophoblast in the physiological change in decidual spiral arteries

    Elisa P.Y. Kam;Lucy Gardner;Y.W. Loke;Ashley King

  • Evidence for the expression of HLAA-C class I mRNA and protein by human first trimester trophoblast.

    A. King;C. Boocock;A. M. Sharkey;L. Gardner

  • Early human decidual cells exhibit NK activity against the K562 cell line but not against first trimester trophoblast.

    Ashley King;Caroline Birkby;Y.W. Loke

  • Human uterine lymphocytes

    A King;T Burrows;S Verma;S Hiby

  • Expression of killer cell inhibitory receptors on human uterine natural killer cells.

    Sanjay Verma;Ashley King;Yung Wai Loke

  • Resistance of HLA-G and HLA-A2 transfectants to lysis by decidual NK cells.

    Gill Chumbley;Ashley King;Kath Robertson;N. Holmes

  • Human trophoblast and JEG choriocarcinoma cells are sensitive to lysis by IL-2-stimulated decidual NK cells.

    Ashley King;Y.W. Loke

  • Trophoblast migration during human placental implantation

    Tanya D. Burrows;Ashley King;Y.W. Loke

  • Molecular studies of trophoblast HLA-G: polymorphism, isoforms, imprinting and expression in preimplantation embryo.

    S.E. Hiby;A. King;A. Sharkey;Y.W. Loke

  • Screening for cytokine messenger ribonucleic acids in purified human decidual lymphocyte populations by the reverse-transcriptase polymerase chain reaction.

    P. P. Jokhi;A. King;A. M. Sharkey;S. K. Smith

  • Recognition of Trophoblast HLA Class I Molecules by Decidual NK Cell Receptors—A Review

    A. King;S.E. Hiby;L. Gardner;S. Joseph

  • EVALUATION OF TROPHOBLAST HLA-G ANTIGEN WITH A SPECIFIC MONOCLONAL ANTIBODY

    Y. W. Loke;A. King;T. Burrows;L. Gardner

Frequent Co-Authors

Lucy Gardner
Lucy Gardner University of Cambridge
Stephen K. Smith
Stephen K. Smith University of Cambridge
Ashley Moffett
Ashley Moffett University of Cambridge
Marco Colonna
Marco Colonna Washington University in St. Louis
Hans-Georg Rammensee
Hans-Georg Rammensee University of Tübingen
Christian Münz
Christian Münz University of Zurich
Stefan Stevanovic
Stefan Stevanovic University of Tübingen
Antonio G. Siccardi
Antonio G. Siccardi IRCCS Ospedale San Raffaele
M. Azim Surani
M. Azim Surani University of Cambridge
John Trowsdale
John Trowsdale University of Cambridge

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