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D-Index
45
Citations
6261
World Ranking
7000
National Ranking
194

Overview

Willem M. Otte is affiliated with Utrecht University in the Netherlands, focusing primarily on medicine, with a significant emphasis on epilepsy research and treatment. Their scholarly output encompasses a substantial body of work related to clinical and methodological aspects of neurology, particularly epilepsy.

Their recent publications span topics including epilepsy surgery outcomes, clinical trial methodology, and neurophysiological interventions. Notable papers include:

  • Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study (2020, The Lancet Neurology)
  • The methodological quality of 176,620 randomized controlled trials published between 1966 and 2018 reveals a positive trend but also an urgent need for improvement (2021, PLoS Biology)
  • Intraoperative electrocorticography using high-frequency oscillations or spikes to tailor epilepsy surgery in the Netherlands (the HFO trial): a randomised, single-blind, adaptive non-inferiority trial (2022, The Lancet Neurology)
  • Transforming epilepsy research: A systematic review on natural language processing applications (2022, Epilepsia)
  • Continuous Theta-Burst Stimulation of the Contralesional Primary Motor Cortex for Promotion of Upper Limb Recovery After Stroke: A Randomized Controlled Trial (2023, Stroke)

Otte collaborates frequently with several researchers, including:

  • Kees P. J. Braun
  • Geertruida Slinger
  • Herm J. Lamberink
  • Floor E. Jansen
  • Rick M. Dijkhuizen

Key publication venues where Otte's work appears often include:

  • Epilepsia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Epilepsia Open
  • Epilepsy & Behavior
  • Epileptic Disorders

Their research engages with multiple subfields, notably:

  • Psychiatry and Mental Health
  • Pediatrics, Perinatology and Child Health
  • Cognitive Neuroscience
  • Statistics, Probability and Uncertainty
  • Statistics and Probability

The main topics of Otte's work cover:

  • Epilepsy research and treatment
  • Pharmacological Effects and Toxicity Studies
  • Meta-analysis and systematic reviews
  • Health Systems, Economic Evaluations, Quality of Life
  • EEG and Brain-Computer Interfaces
  • Neonatal and fetal brain pathology
  • Statistical Methods in Clinical Trials

Best Publications

  • Recovery of Sensorimotor Function after Experimental Stroke Correlates with Restoration of Resting-State Interhemispheric Functional Connectivity

    Maurits P. A. van Meer;Kajo van der Marel;Kun Wang;Willem M. Otte

  • Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study

    Herm J Lamberink;Willem M Otte;Ingmar Blümcke;Kees P J Braun

  • Individualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients: a systematic review and individual participant data meta-analysis.

    Herm J Lamberink;Willem M Otte;Ada T Geerts;Milen Pavlovic

  • Oligodendroglial myelination requires astrocyte-derived lipids.

    Nutabi Camargo;Andrea Goudriaan;Anne-Lieke F van Deijk;Willem M. Otte

  • Extent of Bilateral Neuronal Network Reorganization and Functional Recovery in Relation to Stroke Severity

    Maurits P.A. van Meer;Willem M. Otte;Kajo van der Marel;Cora H. Nijboer

  • Use of positive and negative words in scientific PubMed abstracts between 1974 and 2014: retrospective analysis.

    Christiaan H Vinkers;Joeri K Tijdink;Willem M Otte

  • A meta-analysis of white matter changes in temporal lobe epilepsy as studied with diffusion tensor imaging.

    Willem M. Otte;Pieter van Eijsden;Josemir W. Sander;John S. Duncan

  • Brain Network Organization in Focal Epilepsy: A Systematic Review and Meta-Analysis.

    Eric van Diessen;Willemiek J. E. M. Zweiphenning;Floor E. Jansen;Cornelis J. Stam

  • Tailoring epilepsy surgery with fast ripples in the intraoperative electrocorticogram

    Maryse A. van 't Klooster;Nicole E.C. van Klink;Willemiek J.E.M. Zweiphenning;Frans S.S. Leijten

  • Correspondence between altered functional and structural connectivity in the contralesional sensorimotor cortex after unilateral stroke in rats: a combined resting-state functional MRI and manganese-enhanced MRI study

    Maurits P A van Meer;Kajo van der Marel;Willem M Otte;Jan Willem Berkelbach van der Sprenkel

  • A systematic review on the quantitative relationship between structural and functional network connectivity strength in mammalian brains

    Milou Straathof;Michel Rt Sinke;Rick M Dijkhuizen;Willem M Otte

  • Functional MRI and diffusion tensor imaging of brain reorganization after experimental stroke.

    Rick M. Dijkhuizen;Kajo van der Marel;Willem M. Otte;Erik I. Hoff

  • Intraoperative electrocorticography using high-frequency oscillations or spikes to tailor epilepsy surgery in the Netherlands (the HFO trial): a randomised, single-blind, adaptive non-inferiority trial

    Unknown

  • Longitudinal assessment of blood-brain barrier leakage during epileptogenesis in rats. A quantitative MRI study.

    E.A. van Vliet;W.M. Otte;J.A. Gorter;R.M. Dijkhuizen

  • Effect of health education on trainee teachers' knowledge, attitudes, and first aid management of epilepsy : An interventional study

    Christian N. Eze;Olufunke M. Ebuehi;Francesco Brigo;Willem M. Otte

  • Antiepileptic drug withdrawal in medically and surgically treated patients: a meta-analysis of seizure recurrence and systematic review of its predictors.

    Herm J. Lamberink;Willem M. Otte;Karin Geleijns;Kees P.J. Braun

  • Are high frequency oscillations associated with altered network topology in partial epilepsy

    Eric van Diessen;Judith I. Hanemaaijer;Willem M. Otte;Rina Zelmann

  • Network analysis of auditory hallucinations in nonpsychotic individuals.

    Remko van Lutterveld;Kelly M. J. Diederen;Willem M. Otte;Iris E Sommer

  • Improved diagnosis in children with partial epilepsy using a multivariable prediction model based on EEG network characteristics.

    Eric van Diessen;Willem M. Otte;Kees P. J. Braun;Cornelis J. Stam

  • Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats I: Magnetic resonance imaging.

    Erwin A. van Vliet;Willem M. Otte;Wytse J. Wadman;Eleonora Aronica

  • Characterization of functional and structural integrity in experimental focal epilepsy: reduced network efficiency coincides with white matter changes.

    Willem M. Otte;Rick M. Dijkhuizen;Maurits P. A. van Meer;Wilhelmina S. van der Hel

Frequent Co-Authors

Kees P.J. Braun
Kees P.J. Braun Utrecht University
Josemir W. Sander
Josemir W. Sander University College London
Floor E. Jansen
Floor E. Jansen Utrecht University
Cornelis J. Stam
Cornelis J. Stam Vrije Universiteit Amsterdam
Marian Joëls
Marian Joëls University of Groningen
Francesco Brigo
Francesco Brigo University of Verona
Maeike Zijlmans
Maeike Zijlmans Utrecht University
Raffaele Nardone
Raffaele Nardone Paracelsus Medical University
Frans S.S. Leijten
Frans S.S. Leijten Utrecht University
Gail S. Bell
Gail S. Bell University College London

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