His primary areas of investigation include Biochemistry, Enzyme, Enzymatic synthesis, Polynucleotide and Stereochemistry. His work in Metabolism, Phosphorylation, Oxidation reduction, Nucleotide and Malic enzyme are all subfields of Biochemistry research. His Enzyme study combines topics from a wide range of disciplines, such as Lipid metabolism and Azotobacter.
His Enzymatic synthesis research incorporates themes from Nucleic acid and Citric acid. While the research belongs to areas of Polynucleotide, he spends his time largely on the problem of Amino acid, intersecting his research to questions surrounding Tobacco mosaic virus and Peptide sequence. His Stereochemistry research includes elements of Acetyl-CoA, eIF2, Guanosine diphosphate and GTP', GDP binding.
Severo Ochoa focuses on Biochemistry, Initiation factor, Enzyme, RNA and Protein biosynthesis. Many of his studies involve connections with topics such as Molecular biology and Biochemistry. Severo Ochoa has included themes like Translation and Messenger RNA in his Molecular biology study.
His research integrates issues of Ribosomal RNA, Eukaryotic Small Ribosomal Subunit, GTP' and Eukaryotic initiation factor in his study of Initiation factor. His study looks at the intersection of RNA and topics like Escherichia coli with Transfer RNA. His Metabolism research is multidisciplinary, relying on both Propionates and Cofactor.
Biochemistry, Phosphorylation, Protein biosynthesis, Initiation factor and Reticulocyte are his primary areas of study. His works in Protein kinase A, Heme, Hemin, Protein subunit and GTP' are all subjects of inquiry into Biochemistry. He combines subjects such as Ternary complex, Kinase and G alpha subunit with his study of Phosphorylation.
The various areas that Severo Ochoa examines in his Protein biosynthesis study include Prokaryotic initiation factor and Cell biology. His Initiation factor study combines topics in areas such as Translational regulation, Eukaryotic Small Ribosomal Subunit, eIF2 and Eukaryotic initiation factor. In his study, which falls under the umbrella issue of Molecular biology, Ribosomal RNA, Messenger RNA and Oligonucleotide is strongly linked to RNA.
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[123] Malic dehydrogenase from pig heart: l-Malate + DPN + ⇆ Oxalacetate + DPNH + H+
Severo Ochoa.
Methods in Enzymology (1955)
The enzymatic mechanism of oxidation-reductions between malate or isocitrate and pyruvate.
Alan H. Mehler;Arthur. Kornberg;Santiago. Grisolia;Severo. Ochoa.
Journal of Biological Chemistry (1948)
Enzymatic phosphorylation of acetate.
Irwin A. Rose;Marianne Grunberg-Manago;Saul R. Korey;Severo Ochoa.
Journal of Biological Chemistry (1954)
[124] “Malic”-enzyme
Severo Ochoa.
Methods in Enzymology (1955)
Biosynthesis of dicarboxylic acids by carbon dioxide fixation; isolation and properties of an enzyme from pigeon liver catalyzing the reversible oxidative decarboxylation of 1-malic acid.
Severo. Ochoa;Alan H. Mehler;Arthur. Kornberg.
Journal of Biological Chemistry (1948)
Synthetic polynucleotides and the amino acid code. V.
Carlos Basilio;Albert J. Wahba;Peter Lengyel;Joseph F. Speyer.
Proceedings of the National Academy of Sciences of the United States of America (1962)
Enzymes of fatty acid metabolism.
Feodor Lynen;Severo Ochoa.
Biochimica et Biophysica Acta (1953)
Enzymic synthesis of polynucleotides. I. Polynucleotide phosphorylase of azotobacter vinelandii.
Marianne Grunberg-Manago;Priscilla J. Ortiz;Severo Ochoa.
Biochimica et Biophysica Acta (1956)
Fluorokinase and pyruvic kinase.
Alisa Tietz;Severo Ochoa.
Archives of Biochemistry and Biophysics (1958)
OXIDATION AND REDUCTION OF GLYCOLIC AND GLYOXYLIC ACIDS IN PLANTS I. GLYCOLIC ACID OXIDASE
I. Zelitch;Severo Ochoa.
Journal of Biological Chemistry (1953)
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