World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
21725
World Ranking
3931
National Ranking
1941

Overview

Scott A. Shaffer is affiliated with San Jose State University in the United States. Their research spans multiple disciplines within biochemistry, genetics, and molecular biology, with significant contributions to medicine.

The main fields of study in their work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these, Shaffer's subfields of expertise cover molecular biology, immunology, infectious diseases, genetics, and cellular and molecular neuroscience.

  • Molecular Biology
  • Immunology
  • Infectious Diseases
  • Genetics
  • Cellular and Molecular Neuroscience

Their research topics reflect a focus on immune responses, disease mechanisms, and advanced molecular technologies:

  • SARS-CoV-2 and COVID-19 Research
  • Vaccines and immunoinformatics approaches
  • Immunotherapy and Immune Responses
  • Inflammasome and immune disorders
  • Interferon and immune responses
  • Extracellular vesicles in disease
  • RNA Interference and Gene Delivery

A selection of recent papers authored or co-authored by Shaffer includes:

  • "Succination inactivates gasdermin D and blocks pyroptosis" (2020), published in Science
  • "Human neural cell type-specific extracellular vesicle proteome defines disease-related molecules associated with activated astrocytes in Alzheimer's disease brain" (2022), published in Journal of Extracellular Vesicles
  • "Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells" (2021), published in Immunity
  • "AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice" (2022), published in Nature
  • "ATP1A3 as a target for isolating neuron-specific extracellular vesicles from human brain and biofluids" (2023), published in Science Advances

Frequent co-authors collaborating with Shaffer include:

  • Khaja Muneeruddin
  • Paul R. Thompson
  • Roshanak Aslebagh
  • Nadia Sultana
  • Yang You

The scientist's publications have appeared in several notable venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Science Advances
  • Journal of the American Chemical Society
  • Alzheimer's & Dementia

Best Publications

  • Tracking apex marine predator movements in a dynamic ocean

    Barbara A. Block;I D Jonsen;S J Jorgensen;A J Winship

  • High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.

    Reka A. Haraszti;Marie-Cecile Didiot;Ellen Sapp;John D. Leszyk

  • Migratory shearwaters integrate oceanic resources across the Pacific Ocean in an endless summer.

    Scott A. Shaffer;Yann Tremblay;Henri Weimerskirch;Darren Scott

  • Succination inactivates gasdermin D and blocks pyroptosis

    Fiachra Humphries;Liraz Shmuel-Galia;Natalia Ketelut-Carneiro;Sheng Li

  • Predicted habitat shifts of Pacific top predators in a changing climate

    Elliott L. Hazen;Elliott L. Hazen;Salvador Jorgensen;Ryan R. Rykaczewski;Steven J. Bograd

  • Key Questions in Marine Megafauna Movement Ecology

    Graeme C. Hays;Luciana C. Ferreira;Luciana C. Ferreira;Ana M.M. Sequeira;Mark G. Meekan

  • Exosomes Produced from 3D Cultures of MSCs by Tangential Flow Filtration Show Higher Yield and Improved Activity

    Reka Agnes Haraszti;Rachael Miller;Matteo Stoppato;Yves Y. Sere

  • Transcription factor Foxp3 and its protein partners form a complex regulatory network

    Dipayan Rudra;Paul deRoos;Ashutosh Chaudhry;Rachel E Niec

  • Fast and fuel efficient? Optimal use of wind by flying albatrosses

    Henri Weimerskirch;T Guionnet;J Martin;Scott A Shaffer

  • A novel ion funnel for focusing ions at elevated pressure using electrospray ionization mass spectrometry

    Scott A. Shaffer;Keqi Tang;Gordon A. Anderson;David C. Prior

  • The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus

    Guramrit Singh;Alper Kucukural;Can Cenik;John D. Leszyk

  • Cumulative human impacts on marine predators

    Sara M. Maxwell;Elliott L. Hazen;Elliott L. Hazen;Elliott L. Hazen;Steven J. Bograd;Benjamin S. Halpern;Benjamin S. Halpern

  • Genetic basis of proteome variation in yeast.

    Eric J Foss;Dragan Radulovic;Scott A Shaffer;Douglas M Ruderfer

  • Precursor acquisition independent from ion count: how to dive deeper into the proteomics ocean.

    Alexandre Panchaud;Alexander Scherl;Scott A. Shaffer;Priska D. von Haller

  • An Ion Funnel Interface for Improved Ion Focusing and Sensitivity Using Electrospray Ionization Mass Spectrometry

    Scott A. Shaffer;David C. Prior;Gordon A. Anderson;Harold R. Udseth

  • Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis.

    Bibhuti B. Mishra;Rustin R. Lovewell;Andrew J. Olive;Guoliang Zhang

  • Applying global criteria to tracking data to define important areas for marine conservation

    B. G. Lascelles;P. R. Taylor;M. G. R. Miller;M. P. Dias

  • Perspectives in Ornithology: Application of tracking and data-logging technology in research and conservation of seabirds

    Alan E. Burger;Scott A. Shaffer

  • Lack of In Vitro and In Vivo Recognition of Francisella tularensis Subspecies Lipopolysaccharide by Toll-Like Receptors

    Adeline M. Hajjar;Megan D. Harvey;Scott A. Shaffer;David R. Goodlett

  • Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains

    Laurence Rohmer;Christine Fong;Simone Abmayr;Michael Wasnick

Frequent Co-Authors

Daniel P. Costa
Daniel P. Costa University of California, Santa Cruz
David R. Goodlett
David R. Goodlett University of Victoria
Yann Tremblay
Yann Tremblay Institut de Recherche pour le Développement
Henri Weimerskirch
Henri Weimerskirch Centre national de la recherche scientifique, CNRS
John D. Leszyk
John D. Leszyk University of Massachusetts Chan Medical School
Elliott L. Hazen
Elliott L. Hazen National Oceanic and Atmospheric Administration
David G. Foley
David G. Foley National Oceanic and Atmospheric Administration
František Tureček
František Tureček University of Washington
Richard A. Phillips
Richard A. Phillips British Antarctic Survey
Leigh G. Torres
Leigh G. Torres Oregon State University

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