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Saranjit Singh

Saranjit Singh

Overview

Saranjit Singh is affiliated with McMaster University in Canada and has an extensive research profile primarily within the field of Medicine.

Their work spans several subfields including:

  • Pharmacology
  • Molecular Biology
  • Ophthalmology
  • Infectious Diseases
  • Organic Chemistry

Key research topics covered by Singh include:

  • Drug Transport and Resistance Mechanisms
  • Retinal Diseases and Treatments
  • Pharmacogenetics and Drug Metabolism
  • SARS-CoV-2 and COVID-19 Research
  • Quinazolinone synthesis and applications
  • Antibiotics Pharmacokinetics and Efficacy
  • Drug-Induced Hepatotoxicity and Protection

Singh has contributed multiple publications across a range of scientific journals. Frequently appearing venues include:

  • Journal of Pharmaceutical and Biomedical Analysis
  • Pharmaceutical Research
  • Journal of Chemical Information and Modeling
  • Journal of Pharmaceutical Sciences
  • ACS Omega

Notable recent papers authored or co-authored by Singh are:

  • Structure-Based Virtual Screening to Discover Potential Lead Molecules for the SARS-CoV-2 Main Protease, 2020, Journal of Chemical Information and Modeling
  • Characterization of stress degradation products of nintedanib by UPLC, UHPLC-Q-TOF/MS/MS and NMR: Evidence of a degradation product with a structure alert for mutagenicity, 2021, Journal of Pharmaceutical and Biomedical Analysis
  • Characterization of Photodegradation Products of Bepotastine Besilate and In Silico Evaluation of Their Physicochemical, Absorption, Distribution, Metabolism, Excretion and Toxicity Properties, 2020, Journal of Pharmaceutical Sciences
  • Contribution of Uptake and Efflux Transporters to Oral Pharmacokinetics of Furosemide, 2020, ACS Omega
  • Stress degradation study on entrectinib and characterization of its degradation products using HRMS and NMR, 2021, Journal of Pharmaceutical and Biomedical Analysis

Frequent collaborators in Singh's research include:

  • Ankit Balhara
  • Dilip Kumar Singh
  • Sanjeev Giri
  • Bhagwat Prasad
  • Abdul Basit

Best Publications

  • Development of validated stability-indicating assay methods--critical review.

    Monika Bakshi;Saranjit Singh

  • Lipophilic drug derivatives in liposomes

    Monica Gulati;Manish Grover;Saranjit Singh;Mandip Singh

  • Guidance on Conduct of Stress Tests to Determine Inherent Stability of Drugs

    Saranjit Singh;Monika Bakshi

  • Forced degradation studies to assess the stability of drugs and products

    Saranjit Singh;Mahendra Junwal;Gajanan Modhe;Harsita Tiwari

  • A critical review on the use of modern sophisticated hyphenated tools in the characterization of impurities and degradation products

    Saranjit Singh;Tarun Handa;Mallikarjun Narayanam;Archana Sahu

  • Stress degradation studies on ezetimibe and development of a validated stability-indicating HPLC assay

    Saranjit Singh;Baljinder Singh;Rakesh Bahuguna;Lalit Wadhwa

  • Strategies for characterizing sildenafil, vardenafil, tadalafil and their analogues in herbal dietary supplements, and detecting counterfeit products containing these drugs

    Saranjit Singh;Bhagwat Prasad;Akash A. Savaliya;Ravi P. Shah

  • Metabolite identification by liquid chromatography-mass spectrometry

    Bhagwat Prasad;Amit Garg;Hardik Takwani;Saranjit Singh

  • The ICH guidance in practice: stress degradation studies on ornidazole and development of a validated stability-indicating assay

    Monika Bakshi;Baljinder Singh;Amarjit Singh;Saranjit Singh

  • LC and LC-MS study of stress decomposition behaviour of isoniazid and establishment of validated stability-indicating assay method

    Hemant Bhutani;Saranjit Singh;Sanjay Vir;K.K. Bhutani

  • The Reason for an Increase in Decomposition of Rifampicin in the Presence of Isoniazid under Acid Conditions

    Saranjit Singh;T. T. Mariappan;Nishi Sharda;Sanjeev Kumar

  • Critical practical aspects in the application of liquid chromatography–mass spectrometric studies for the characterization of impurities and degradation products

    Mallikarjun Narayanam;Tarun Handa;Parul Sharma;Shalu Jhajra

  • Quantitative structure-property relationships in pharmaceutical research - Part 2.

    Manish Grover;Bhupinder Singh;Monika Bakshi;Saranjit Singh

  • A critical review of the probable reasons for the poor variable bioavailability of rifampicin from anti-tubercular fixed-dose combination (FDC) products, and the likely solutions to the problem.

    Saranjit Singh;T.T Mariappan;R Shankar;N Sarda

  • Stability of anthocyanins- and anthocyanidins-enriched extracts, and formulations of fruit pulp of Eugenia jambolana (‘jamun’)

    Ram Jee Sharma;Ramesh C. Gupta;Saranjit Singh;Arvind Kumar Bansal

  • Structure-Based Virtual Screening to Discover Potential Lead Molecules for the SARS-CoV-2 Main Protease.

    Anuj Gahlawat;Navneet Kumar;Rajender Kumar;Hardeep Sandhu

  • Study of forced degradation behavior of enalapril maleate by LC and LC–MS and development of a validated stability-indicating assay method

    Sunny Piyush Bhardwaj;Saranjit Singh

  • Alteration in Dissolution Characteristics of Gelatin-Containing Formulations A Review of the Problem, Test Methods, and Solutions

    Saranjit Singh;K. V. Rama Rao;K. Venugopal;R. Manikandan

  • Evaluation of the recently reported USP gradient HPLC method for analysis of anti-tuberculosis drugs for its ability to resolve degradation products of rifampicin.

    Bhavika Mohan;Nishi Sharda;Saranjit Singh

  • A Comprehensive Computer Program For The Study Of Drug Release Kinetics From Compressed Matrices

    Bhupinder Singh;Saranjit Singh

Frequent Co-Authors

Asit K. Chakraborti
Asit K. Chakraborti University of Burdwan
Mark Halpern
Mark Halpern University of British Columbia
Bryan Gaensler
Bryan Gaensler University of California, Santa Cruz
Scott M. Ransom
Scott M. Ransom National Radio Astronomy Observatory
Keith Vanderlinde
Keith Vanderlinde University of Toronto
Ue-Li Pen
Ue-Li Pen University of Toronto
Ingrid H. Stairs
Ingrid H. Stairs University of British Columbia
Jason W. T. Hessels
Jason W. T. Hessels University of Amsterdam
Victoria M. Kaspi
Victoria M. Kaspi McGill University
Archie E. Hamielec
Archie E. Hamielec McMaster University

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