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Roland R. Regoes

Roland R. Regoes

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
9419
World Ranking
17167
National Ranking
320

Overview

Roland R. Regoes is affiliated with ETH Zurich in Switzerland and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, as well as medicine. Their research covers a broad spectrum of topics with a particular focus on evolutionary and genetic dynamics, antibiotic resistance in bacteria, and infectious diseases.

Regoes has published numerous articles across various scientific journals, including:

  • Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression (2020, Mucosal Immunology)
  • Population genetics, biofilm recalcitrance, and antibiotic resistance evolution (2022, Trends in Microbiology)
  • Bacteria primed by antimicrobial peptides develop tolerance and persist (2021, PLoS Pathogens)
  • Multi-step vs. single-step resistance evolution under different drugs, pharmacokinetics, and treatment regimens (2021, eLife)
  • Decomposing virulence to understand bacterial clearance in persistent infections (2022, Nature Communications)

The scientist collaborates frequently with other researchers, with some of the most common co-authors being Sebastian Bonhoeffer, Judith A. Bouman, Jens Rolff, Christopher Witzany, and Barbora Trubenová.

Regoes' work is often published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the Royal Society B Biological Sciences
  • PLoS Computational Biology
  • Trends in Microbiology
  • PLoS Biology

The main fields of study addressed in Regoes' research include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader areas, they focus on several subfields including genetics, infectious diseases, virology, molecular biology, and molecular medicine.

The primary scientific themes explored in the research include:

  • Evolution and Genetic Dynamics
  • Antibiotic Resistance in Bacteria
  • HIV Research and Treatment
  • COVID-19 epidemiological studies
  • Bacteriophages and microbial interactions
  • SARS-CoV-2 and COVID-19 Research
  • Mathematical and Theoretical Epidemiology and Ecology Models

Best Publications

  • The role of evolution in the emergence of infectious diseases

    Rustom Antia;Roland R. Regoes;Jacob C. Koella;Carl T. Bergstrom

  • High-avidity IgA protects the intestine by enchaining growing bacteria

    Kathrin Moor;Médéric Diard;Mikael E. Sellin;Mikael E. Sellin;Boas Felmy

  • Pharmacodynamic Functions: a Multiparameter Approach to the Design of Antibiotic Treatment Regimens

    Roland R. Regoes;Camilla Wiuff;Renata M. Zappala;Kim N. Garner

  • Stabilization of cooperative virulence by the expression of an avirulent phenotype

    Médéric Diard;Victor Garcia;Lisa Maier;Mitja N. P. Remus-Emsermann

  • Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation

    Hitoshi Takizawa;Roland R. Regoes;Chandra S. Boddupalli;Sebastian Bonhoeffer

  • Population biological principles of drug-resistance evolution in infectious diseases

    Pia Abel zur Wiesch;Roger Kouyos;Jan Engelstädter;Roland R Regoes

  • Phenotypic Tolerance: Antibiotic Enrichment of Noninherited Resistance in Bacterial Populations

    C. Wiuff;R. M. Zappala;R. R. Regoes;K. N. Garner

  • The HIV coreceptor switch: a population dynamical perspective.

    Roland R. Regoes;Sebastian Bonhoeffer

  • Investigating the Consequences of Interference between Multiple CD8+ T Cell Escape Mutations in Early HIV Infection.

    Victor Garcia;Marcus W. Feldman;Roland R. Regoes

  • Combination Effects of Antimicrobial Peptides

    Guozhi Yu;Desiree Y. Baeder;Roland R. Regoes;Jens Rolff

  • Emergence of drug-resistant influenza virus: population dynamical considerations.

    Roland R. Regoes;Sebastian Bonhoeffer

  • Insect antimicrobial peptides show potentiating functional interactions against Gram-negative bacteria.

    Mohammad Rahnamaeian;Małgorzata Cytryńska;Agnieszka Zdybicka-Barabas;Kristin Dobslaff

  • Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut

    Erik Bakkeren;Jana S. Huisman;Jana S. Huisman;Stefan A. Fattinger;Stefan A. Fattinger;Annika Hausmann

  • Evolution of virulence in a heterogeneous host population

    Roland R. Regoes;Martin A. Nowak;Sebastian Bonhoeffer

  • Determinants of HIV-1 broadly neutralizing antibody induction

    Peter Rusert;Roger D Kouyos;Claus Kadelka;Hanna Ebner

  • Predicting drug resistance evolution: insights from antimicrobial peptides and antibiotics.

    Guozhi Yu;Desiree Y. Baeder;Roland R. Regoes;Jens Rolff

  • Dose-dependent infection rates of parasites produce the Allee effect in epidemiology.

    Roland R. Regoes;Dieter Ebert;Sebastian Bonhoeffer

  • Cecum lymph node dendritic cells harbor slow-growing bacteria phenotypically tolerant to antibiotic treatment.

    Patrick Kaiser;Roland R. Regoes;Tamas Dolowschiak;Sandra Y. Wotzka

  • The role of compensatory mutations in the emergence of drug resistance.

    Andreas Handel;Roland R Regoes;Rustom Antia

  • Supplementary material from "Predicting drug resistance evolution: insights from antimicrobial peptides and antibiotics"

    Guozhi Yu;Desiree Y. Baeder;Roland R. Regoes;Jens Rolff

Frequent Co-Authors

Rustom Antia
Rustom Antia Emory University
Alexandra Trkola
Alexandra Trkola University of Zurich
Huldrych F. Günthard
Huldrych F. Günthard University of Zurich
Roger D. Kouyos
Roger D. Kouyos University of Zurich
Mark B. Feinberg
Mark B. Feinberg International AIDS Vaccine Initiative
Andri Rauch
Andri Rauch University of Bern
Karin J. Metzner
Karin J. Metzner University of Zurich
Jürg Böni
Jürg Böni University of Zurich

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