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Genetics

D-Index
58
Citations
12328
World Ranking
3319
National Ranking
12

Research.com Recognitions

  • 1989 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Robert Lyle is affiliated with Oslo University Hospital in Norway and conducts research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields, including Molecular Biology, Pediatrics, Perinatology and Child Health, Pulmonary and Respiratory Medicine, Cancer Research, and Public Health, Environmental and Occupational Health.

The scientist's research topics cover areas such as Epigenetics and DNA Methylation, Prenatal Screening and Diagnostics, Birth, Development, and Health, Assisted Reproductive Technology and Twin Pregnancy, Single-cell and Spatial Transcriptomics, Neonatal Respiratory Health Research, and Maternal Mental Health During Pregnancy and Postpartum.

Among their recent published works are:

  • DNA methylation in newborns conceived by assisted reproductive technology, 2022, Nature Communications
  • An EPIC predictor of gestational age and its application to newborns conceived by assisted reproductive technologies, 2021, Clinical Epigenetics
  • The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants, 2021, BMC Cancer
  • Blood-based epigenetic estimators of chronological age in human adults using DNA methylation data from the Illumina MethylationEPIC array, 2020, BMC Genomics
  • DNA methylation in cord blood in association with prenatal depressive symptoms, 2021, Clinical Epigenetics

Frequent collaborators in Robert Lyle's research include:

  • Christian M. Page
  • Kristina Gervin
  • Magnus Leithaug
  • Siri E. Håberg
  • Håkon K. Gjessing

Their publications are often found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Epigenetics
  • SSRN Electronic Journal
  • iScience
  • Communications Biology

Robert Lyle's career includes recognition as a Fellow of the American Association for the Advancement of Science (AAAS) awarded in 1989.

Best Publications

  • Chromosome 21 and down syndrome: from genomics to pathophysiology.

    Stylianos E. Antonarakis;Robert Lyle;Emmanouil T. Dermitzakis;Alexandre Reymond

  • Genome-Wide Associations of Gene Expression Variation in Humans

    Barbara E Stranger;Matthew S Forrest;Andrew G Clark;Andrew G Clark;Mark J Minichiello

  • Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

    Mario Leonardo Squadrito;Caroline Baer;Frédéric Burdet;Claudio Maderna

  • Increasing prevalence of medically complex children in US hospitals.

    Katherine H. Burns;Patrick H. Casey;Robert E. Lyle;T. Mac Bird

  • Analysis of the tandem repeat locus D4Z4 associated with facioscapulohumeral muscular dystrophy.

    Jane E. Hewitt;Jane E. Hewitt;Robert Lyle;Lorraine N. Clark;Elizabeth M. Valleley

  • Molecular regulation of adipocyte differentiation.

    Robert M. Cowherd;Robert E. Lyle;Robert E. McGehee

  • Meiotic and epigenetic defects in Dnmt3L-knockout mouse spermatogenesis

    Kylie E Webster;Moira Kathleen O'Bryan;Stephen Fletcher;Pauline E Crewther

  • Genotype–phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21

    Robert Lyle;Robert Lyle;Frédérique Béna;Frédérique Béna;Sarantis Gagos;Sarantis Gagos;Corinne Gehrig;Corinne Gehrig

  • The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1.

    Lyle R;Lyle R;Watanabe D;te Vruchte D;Lerchner W

  • Numerous potentially functional but non-genic conserved sequences on human chromosome 21

    Emmanouil T. Dermitzakis;Alexandre Reymond;Robert Lyle;Nathalie Scamuffa

  • Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders.

    Asbjørg Stray-Pedersen;Hanne Sørmo Sorte;Pubudu Samarakoon;Tomasz Gambin;Tomasz Gambin

  • Human chromosome 21 gene expression atlas in the mouse

    Alexandre Reymond;Alexandre Reymond;Valeria Marigo;Murat B. Yaylaoglu;Antonio Leoni

  • Natural Gene-Expression Variation in Down Syndrome Modulates the Outcome of Gene-Dosage Imbalance

    Paola Prandini;Samuel Deutsch;Robert Lyle;Maryline Gagnebin

  • Gene Expression From the Aneuploid Chromosome in a Trisomy Mouse Model of Down Syndrome

    Robert Lyle;Corinne Gehrig;Charlotte Neergaard-Henrichsen;Samuel Deutsch

  • Age-Related Somatic Structural Changes in the Nuclear Genome of Human Blood Cells

    Lars A. Forsberg;Chiara Rasi;Hamid R. Razzaghian;Geeta Pakalapati

  • miR-511-3p modulates genetic programs of tumor-associated macrophages.

    Mario Leonardo Squadrito;Ferdinando Pucci;Laura Magri;Davide Moi

  • A Dominant STIM1 Mutation Causes Stormorken Syndrome

    Doriana Misceo;Asbjørn Holmgren;William E. Louch;Pål A. Holme

  • Submicroscopic Deletion in Patients with Williams-Beuren Syndrome Influences Expression Levels of the Nonhemizygous Flanking Genes

    Giuseppe Merla;Cédric Howald;Charlotte N. Henrichsen;Robert Lyle

  • Regulation and Expression of Retinoblastoma Proteins p107 and p130 during 3T3-L1 Adipocyte Differentiation

    Victoria M. Richon;Robert E. Lyle;Robert E. McGehee

  • Human chromosome 21 gene expression atlas in the mouse.

    Valeria Marigo;A. Reymond;M. B. Yaylaoglu;A. Leoni

Frequent Co-Authors

Stylianos E. Antonarakis
Stylianos E. Antonarakis University of Geneva
Alexandre Reymond
Alexandre Reymond University of Lausanne
Emmanouil T. Dermitzakis
Emmanouil T. Dermitzakis University of Geneva
Jean-Louis Blouin
Jean-Louis Blouin University of Geneva
Kirsi H. Pietiläinen
Kirsi H. Pietiläinen University of Helsinki
Kai-Håkon Carlsen
Kai-Håkon Carlsen University of Oslo
Andreas Keller
Andreas Keller Saarland University
Jaakko Kaprio
Jaakko Kaprio University of Helsinki
Eckart Meese
Eckart Meese Saarland University
Hamish S. Scott
Hamish S. Scott University of Adelaide

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