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Neuroscience

D-Index
58
Citations
11236
World Ranking
4187
National Ranking
1896

Overview

Ralph Lydic is affiliated with the University of Tennessee at Knoxville in the United States. Their research primarily focuses on neuroscience, with a significant body of work spanning several subfields including cellular and molecular neuroscience, cognitive neuroscience, physiology, endocrine and autonomic systems, and molecular biology.

The scientist's recent published papers encompass diverse topics related to neurophysiology and neuropharmacology. Notable publications include:

  • Neuronal mechanisms underlying opioid-induced respiratory depression: our current understanding (2021) in Journal of Neurophysiology
  • Evidence for long-term potentiation in phospholipid membranes (2022) in Proceedings of the National Academy of Sciences
  • Neurotransmitter networks in mouse prefrontal cortex are reconfigured by isoflurane anesthesia (2020) in Journal of Neurophysiology
  • Isoflurane anesthesia disrupts the cortical metabolome (2020) in Journal of Neurophysiology
  • Opioids cause dissociated states of consciousness in C57BL/6J mice (2021) in Journal of Neurophysiology

Frequent thematic areas of their work include neuroscience and neuropharmacology research, sleep and wakefulness research, adipose tissue and metabolism, neuroscience of respiration and sleep, lipid membrane structure and behavior, tryptophan and brain disorders, and memory and neural mechanisms.

The scientist has collaborated extensively with several coauthors, notably:

  • Helen A. Baghdoyan (19 publications)
  • Joshua Price (7 publications)
  • Diana Zebadúa Unzaga (7 publications)
  • Zachary T. Glovak (6 publications)
  • Xiaojuan Zhu (4 publications)

Ralph Lydic's research has been published predominantly in journals such as Journal of Neurophysiology, Journal of Pharmacology and Experimental Therapeutics, The FASEB Journal, Respiratory Physiology & Neurobiology, and Proceedings of the National Academy of Sciences. The Journal of Neurophysiology features the largest number of their articles.

The range of research topics and publication venues indicate a multidisciplinary approach focused on understanding the neural and physiological mechanisms related to respiration, anesthesia, opioid effects, and neural plasticity. Their work contributes to various aspects of neuroscience from molecular processes to systemic physiological effects.

Best Publications

  • General anesthesia, sleep, and coma

    Emery N. Brown;Ralph Lydic;Nicholas D. Schiff

  • Perineural Administration of Dexmedetomidine in Combination with Bupivacaine Enhances Sensory and Motor Blockade in Sciatic Nerve Block without Inducing Neurotoxicity in Rat

    Chad M. Brummett;Mary A. Norat;John M. Palmisano;Ralph Lydic

  • Perineural Dexmedetomidine Added to Ropivacaine for Sciatic Nerve Block in Rats Prolongs the Duration of Analgesia by Blocking the Hyperpolarization-activated Cation Current

    Chad M. Brummett;Elizabeth K. Hong;Allison M. Janda;Francesco S. Amodeo

  • Evolving concepts of sleep cycle generation: From brain centers to neuronal populations

    J. A. Hobson;R. Lydic;H. A. Baghdoyan

  • Perineural dexmedetomidine added to ropivacaine causes a dose-dependent increase in the duration of thermal antinociception in sciatic nerve block in rat.

    Chad M. Brummett;Amrita K. Padda;Francesco S. Amodeo;Kathleen B. Welch

  • Sleep, anesthesiology, and the neurobiology of arousal state control.

    Ralph Lydic;Helen A. Baghdoyan

  • Pontogeniculooccipital waves: spontaneous visual system activity during rapid eye movement sleep

    C W Callaway;R Lydic;R Lydic;H A Baghdoyan;H A Baghdoyan;J A Hobson

  • Pontine Nitric Oxide Modulates Acetylcholine Release, Rapid Eye Movement Sleep Generation, and Respiratory Rate

    Timothy O. Leonard;Ralph Lydic

  • The carbachol-induced enhancement of desynchronized sleep signs is dose dependent and antagonized by centrally administered atropine.

    H A Baghdoyan;R Lydic;C W Callaway;J A Hobson

  • Circadian rhythm of body temperature persists after suprachiasmatic lesions in the squirrel monkey

    C. A. Fuller;R. Lydic;F. M. Sulzman;H. E. Albers

  • Pedunculopontine stimulation alters respiration and increases ACh release in the pontine reticular formation.

    R. Lydic;H. A. Baghdoyan

  • Adenosine A1 and A2A Receptors in Mouse Prefrontal Cortex Modulate Acetylcholine Release and Behavioral Arousal

    Christa J. Van Dort;Helen A. Baghdoyan;Ralph Lydic

  • M2 muscarinic receptor subtype in the feline medial pontine reticular formation modulates the amount of rapid eye movement sleep.

    Helen A. Baghdoyan;R. Lydic

  • Suprachiasmatic region of the human hypothalamus: homolog to the primate circadian pacemaker?

    R Lydic;W C Schoene;C A Czeisler;M C Moore-Ede

  • Perineural dexmedetomidine provides an increased duration of analgesia to a thermal stimulus when compared with a systemic control in a rat sciatic nerve block.

    Chad M. Brummett;Francesco S. Amodeo;Allison M. Janda;Amrita K. Padda

  • Neuropharmacology of Sleep and Wakefulness.

    Christopher J. Watson;Helen A. Baghdoyan;Ralph Lydic

  • Respiratory neurons of the pneumotaxic center during sleep and wakefulness.

    R. Lydic;J. Orem

  • Opioid inhibition of rapid eye movement sleep by a specific mu receptor agonist

    A. Cronin;J.C. Keifer;H.A. Baghdoyan;R. Lydic

  • Upper Airway Function During Sleep and Wakefulness: Experimental Studies on Normal and Anesthetized Cats

    John Orem;Ralph Lydic

  • Handbook of Behavioral State Control : Cellular and Molecular Mechanisms

    Ralph Lydic;Helen A. Baghdoyan

Frequent Co-Authors

Helen A. Baghdoyan
Helen A. Baghdoyan University of Michigan–Ann Arbor
Robert W. McCarley
Robert W. McCarley Harvard Medical School
George A. Mashour
George A. Mashour University of Michigan–Ann Arbor
Giulio Tononi
Giulio Tononi University of Wisconsin–Madison
Nicholas D. Schiff
Nicholas D. Schiff Cornell University
Robert A. Pearce
Robert A. Pearce University of Wisconsin–Madison
Michael T. Alkire
Michael T. Alkire University of California, Irvine
Max B. Kelz
Max B. Kelz University of Pennsylvania
Frances Chung
Frances Chung University Health Network

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