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Ralph J. DiLeone

Ralph J. DiLeone

D-Index & Metrics

Neuroscience

D-Index
64
Citations
21391
World Ranking
3212
National Ranking
1489

Overview

Ralph J. DiLeone is affiliated with Yale University in the United States. Their research spans various areas within neuroscience and neuropharmacology, with a particular focus on receptor mechanisms, brain disorders, and behavioral neuroscience.

Their recent publications cover diverse topics related to neurobiology, behavior, and metabolism. Key papers include:

  • Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice (2020, Nature Neuroscience)
  • Brain responses to nutrients are severely impaired and not reversed by weight loss in humans with obesity: a randomized crossover study (2023, Nature Metabolism)
  • Medial Nucleus Accumbens Projections to the Ventral Tegmental Area Control Food Consumption (2020, Journal of Neuroscience)
  • Orexin 1 Receptor Antagonism in the Basolateral Amygdala Shifts the Balance From Pro- to Antistress Signaling and Behavior (2022, Biological Psychiatry)
  • Ketamine increases vmPFC activity: Effects of (R)- and (S)-stereoisomers and (2R,6R)-hydroxynorketamine metabolite (2020, Neuropharmacology)

The scientist has collaborated frequently with several coauthors, including Anissa Abi-Dargham, Deanna M. Barch, and Edward T. Bullmore, among others. Some collaborations are also linked with locations such as New York and St Louis.

Their work is published predominantly in these venues:

  • Biological Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Neuroscience
  • Nature Metabolism
  • Translational Psychiatry

Ralph J. DiLeone's research encompasses several subfields of study, including:

  • Cellular and Molecular Neuroscience
  • Biological Psychiatry
  • Endocrine and Autonomic Systems
  • Pharmacology
  • Physiology

Their main research topics involve:

  • Tryptophan and brain disorders
  • Treatment of Major Depression
  • Neurotransmitter Receptor Influence on Behavior
  • Neuroscience and Neuropharmacology Research
  • Stress Responses and Cortisol
  • Regulation of Appetite and Obesity
  • Receptor Mechanisms and Signaling

Best Publications

  • Neurobiology of depression.

    Eric J. Nestler;Michel Barrot;Ralph J. DiLeone;Amelia J. Eisch

  • Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress

    Olivier Berton;Colleen A. McClung;Ralph J. DiLeone;Vaishnav Krishnan

  • Leptin Receptor Signaling in Midbrain Dopamine Neurons Regulates Feeding

    Jonathan D. Hommel;Richard Trinko;Richard Trinko;Robert M. Sears;Dan Georgescu

  • CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli

    Michel Barrot;Jocelien D A Olivier;Linda I Perrotti;Ralph J DiLeone

  • Dynamic contribution of nestin-expressing stem cells to adult neurogenesis.

    Diane C. Lagace;Mary C. Whitman;Michele A. Noonan;Jessica L. Ables

  • Nicotine Decreases Food Intake Through Activation of POMC Neurons

    Yann S. Mineur;Alfonso Abizaid;Yan Rao;Ramiro Salas

  • Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse

    Danielle L Graham;Scott Edwards;Ryan K Bachtell;Ralph J DiLeone

  • Local gene knockdown in the brain using viral-mediated RNA interference

    Jonathan D Hommel;Robert M Sears;Dan Georgescu;Diana L Simmons

  • Involvement of the Lateral Hypothalamic Peptide Orexin in Morphine Dependence and Withdrawal

    Dan Georgescu;Venetia Zachariou;Michel Barrot;Michel Barrot;Michihiro Mieda

  • Leptin Mediates the Increase in Blood Pressure Associated with Obesity

    Stephanie E. Simonds;Jack T. Pryor;Eric Ravussin;Frank L. Greenway

  • The Hypothalamic Neuropeptide Melanin-Concentrating Hormone Acts in the Nucleus Accumbens to Modulate Feeding Behavior and Forced-Swim Performance

    Dan Georgescu;Robert M. Sears;Robert M. Sears;Jonathan D. Hommel;Michel Barrot

  • An essential role for DeltaFosB in the nucleus accumbens in morphine action.

    Venetia Zachariou;Carlos A Bolanos;Carlos A Bolanos;Dana E Selley;David Theobald

  • RGS9 Modulates Dopamine Signaling in the Basal Ganglia

    Zia Rahman;Zia Rahman;Johannes Schwarz;Stephen J. Gold;Stephen J. Gold;Venetia Zachariou

  • Essential role for RGS9 in opiate action

    Venetia Zachariou;Dan Georgescu;Nick Sanchez;Zia Rahman

  • The drive to eat: comparisons and distinctions between mechanisms of food reward and drug addiction

    Ralph J DiLeone;Jane R Taylor;Marina R Picciotto

  • REDD1 is essential for stress-induced synaptic loss and depressive behavior

    Kristie T Ota;Rong-Jian Liu;Bhavya Voleti;Jaime G Maldonado-Aviles

  • Optogenetic stimulation of infralimbic PFC reproduces ketamine’s rapid and sustained antidepressant actions

    Manabu Fuchikami;Alexandra Thomas;Rongjian Liu;Eric S. Wohleb

  • Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation.

    Matthew R. Hayes;Karolina P. Skibicka;Theresa M. Leichner;Douglas J. Guarnieri

  • Knockdown of Clock in the Ventral Tegmental Area Through RNA Interference Results in a Mixed State of Mania and Depression-Like Behavior

    Shibani Mukherjee;Laurent Coque;Jun Li Cao;Jaswinder Kumar

  • Lateral hypothalamic neuropeptides in reward and drug addiction.

    Ralph J DiLeone;Dan Georgescu;Eric J Nestler

Frequent Co-Authors

Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai
Jane R. Taylor
Jane R. Taylor Yale University
Ronald S. Duman
Ronald S. Duman Yale University
Nandakumar S. Narayanan
Nandakumar S. Narayanan University of Iowa
Olivier Berton
Olivier Berton University of Pennsylvania
Michel Barrot
Michel Barrot Centre national de la recherche scientifique, CNRS
Shannon L. Gourley
Shannon L. Gourley Emory University
Lisa M. Monteggia
Lisa M. Monteggia Vanderbilt University
Thomas A. Green
Thomas A. Green The University of Texas Medical Branch at Galveston
Scott J. Russo
Scott J. Russo Icahn School of Medicine at Mount Sinai

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