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Chemistry

D-Index
71
Citations
15673
World Ranking
5656
National Ranking
1745

Research.com Recognitions

  • 2010 - Fellow of American Physical Society (APS) Citation For his pioneering work on the thermodynamics and kinetics of protein aggregation and  the discovery of a novel mechanism of nucleation of protein and smallmolecule solid phases in solution

Overview

Peter G. Vekilov is affiliated with the University of Houston in the United States. Their research primarily focuses on Materials Science, with a significant concentration in Materials Chemistry. Additional subfields of study include Molecular Biology, Biomaterials, Public Health, Environmental and Occupational Health, and Atomic and Molecular Physics, and Optics.

The main topics covered in their research include:

  • Crystallization and Solubility Studies
  • Calcium Carbonate Crystallization and Inhibition
  • Protein Structure and Dynamics
  • Enzyme Structure and Function
  • Malaria Research and Control
  • Nanoparticles nucleation surface interactions
  • Alzheimer's disease research and treatments

Peter G. Vekilov has published extensively in several scientific journals. Frequent publication venues include:

  • Crystal Growth & Design
  • Proceedings of the National Academy of Sciences
  • Journal of Biological Chemistry
  • Faraday Discussions
  • Journal of Crystal Growth

Recent notable papers authored or coauthored by Vekilov include:

  • "Antagonistic cooperativity between crystal growth modifiers" (2020, Nature)
  • "Mesoscopic protein-rich clusters host the nucleation of mutant p53 amyloid fibrils" (2021, Proceedings of the National Academy of Sciences)
  • "A second mechanism employed by artemisinins to suppress Plasmodium falciparum hinges on inhibition of hematin crystallization" (2020, Journal of Biological Chemistry)
  • "Understanding crystal nucleation mechanisms: where do we stand? General discussion" (2022, Faraday Discussions)
  • "Two-Step Crystal Nucleation Is Selected Because of a Lower Surface Free Energy Barrier" (2021, Crystal Growth & Design)

Frequent collaborators in Vekilov's research include:

  • Jeffrey D. Rimer
  • Lakshmanji Verma
  • Rajshree Chakrabarti
  • Jeremy C. Palmer
  • David Sullivan

Among the honors received, Vekilov was named a Fellow of the American Physical Society (APS) in 2010. The citation recognized their work on the thermodynamics and kinetics of protein aggregation as well as the discovery of novel nucleation mechanisms for protein and small-molecule solid phases in solution.

Best Publications

  • Principles of crystal nucleation and growth

    James J. De Yoreo;Peter G. Vekilov

  • The two-step mechanism of nucleation of crystals in solution.

    Peter G. Vekilov

  • Nucleation

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  • Dense Liquid Precursor for the Nucleation of Ordered Solid Phases from Solution

    Peter G. Vekilov

  • Control of protein crystal nucleation around the metastable liquid–liquid phase boundary

    Oleg Galkin;Peter G. Vekilov

  • Quasi-planar nucleus structure in apoferritin crystallization

    S.-T. Yau;Peter G. Vekilov

  • Entropy and surface engineering in protein crystallization.

    Zygmunt S. Derewenda;Peter G. Vekilov

  • Are Nucleation Kinetics of Protein Crystals Similar to Those of Liquid Droplets

    Oleg Galkin‡ and;Peter G. Vekilov

  • Liquid-liquid Separation in Solutions of Normal and Sickle Cell Hemoglobin

    Oleg Galkin;Kai Chen;Ronald L. Nagel;Rhoda Elison Hirsch

  • Direct Determination of the Nucleation Rates of Protein Crystals

    O. Galkin;P. G. Vekilov

  • Nucleation and Crystallization of Globular Proteins: What we Know and What is Missing

    F. Rosenberger;P.G. Vekilov;M. Muschol;B.R. Thomas

  • Mechanisms of hematin crystallization and inhibition by the antimalarial drug chloroquine

    Katy N. Olafson;Megan A. Ketchum;Jeffrey D. Rimer;Peter G. Vekilov

  • What Determines the Rate of Growth of Crystals from Solution

    Peter G. Vekilov

  • Two-step mechanism for the nucleation of crystals from solution

    Peter G. Vekilov

  • Two types of amorphous protein particles facilitate crystal nucleation

    Tomoya Yamazaki;Tomoya Yamazaki;Yuki Kimura;Peter G. Vekilov;Erika Furukawa

  • A Metastable Prerequisite for the Growth of Lumazine Synthase Crystals

    Olga Gliko;Nikolaus Neumaier;Weichun Pan;Ilka Haase

  • Evidence for Non-DLVO Hydration Interactions in Solutions of the Protein Apoferritin

    Dimiter N. Petsev;Peter G. Vekilov

  • Interactions and aggregation of apoferritin molecules in solution: effects of added electrolytes.

    Dimiter N. Petsev;Bill R. Thomas;Bill R. Thomas;S.-T. Yau;Peter G. Vekilov

  • Kinetics of two-step nucleation of crystals

    Dimo Kashchiev;Peter G. Vekilov;Anatoly B. Kolomeisky

  • Nucleation of ordered solid phases of proteins via a disordered high-density state: Phenomenological approach

    Weichun Pan;Anatoly B. Kolomeisky;Peter G. Vekilov

  • Dependence of lysozyme growth kinetics on step sources and impurities

    P.G. Vekilov;F. Rosenberger

  • Dense Liquid Precursor for the Nucleation of Ordered Solid Phases from Solution, Crystal Growth and Design

    Peter G. Vekilov

Frequent Co-Authors

Jeffrey D. Rimer
Jeffrey D. Rimer University of Houston
Ronald L. Nagel
Ronald L. Nagel Albert Einstein College of Medicine
Anatoly B. Kolomeisky
Anatoly B. Kolomeisky Rice University
James J. De Yoreo
James J. De Yoreo Pacific Northwest National Laboratory
Helmut Cölfen
Helmut Cölfen University of Konstanz
Haihua Pan
Haihua Pan Zhejiang University
Åke C. Rasmuson
Åke C. Rasmuson University of Limerick
Sarah L. Price
Sarah L. Price University College London
Roger J. Davey
Roger J. Davey University of Manchester

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