World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
85312
World Ranking
3224
National Ranking
1630

Overview

What is he best known for?

The fields of study he is best known for:

  • DNA
  • Gene
  • Genome

His main research concerns Genetics, Genome, DNA, Nucleic acid analogue and Nucleic acid. His research related to DNA sequencing, Human genome, Sequence analysis, DNA sequencing theory and Shotgun sequencing might be considered part of Genetics. His research investigates the connection with DNA sequencing theory and areas like Cancer genome sequencing which intersect with concerns in Paired-end tag, Massive parallel sequencing and Hybrid genome assembly.

His studies examine the connections between Genome and genetics, as well as such issues in Botany, with regards to Genomics. His DNA research is multidisciplinary, incorporating perspectives in Nucleic acid thermodynamics and Stereochemistry. His Nucleic acid study necessitates a more in-depth grasp of Biochemistry.

His most cited work include:

  • Genome sequencing in microfabricated high-density picolitre reactors (7254 citations)
  • A core gut microbiome in obese and lean twins (5272 citations)
  • Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide (3066 citations)

What are the main themes of his work throughout his whole career to date?

Nucleic acid, Biochemistry, DNA, Genetics and Peptide nucleic acid are his primary areas of study. His Nucleic acid research is multidisciplinary, relying on both Nucleic acid structure, Nucleobase, Stereochemistry, Nucleic acid analogue and Peptide. His Biochemistry study integrates concerns from other disciplines, such as Molecular biology and RNA polymerase II.

Michael Egholm mostly deals with A-DNA in his studies of DNA. His work is connected to DNA sequencing, Genome, Gene, Whole Genome Amplification and Pyrosequencing, as a part of Genetics. His Peptide nucleic acid research includes elements of Hybridization probe, Coding strand, Polymerase and Oligonucleotide.

He most often published in these fields:

  • Nucleic acid (34.29%)
  • Biochemistry (29.29%)
  • DNA (27.86%)

What were the highlights of his more recent work (between 2007-2018)?

  • Genetics (25.71%)
  • Virology (10.00%)
  • DNA sequencing (10.00%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Genetics, Virology, DNA sequencing, Genome and Pyrosequencing. His studies in Amplicon, Gene, Sequence analysis, Gene rearrangement and Mitochondrial DNA are all subfields of Genetics research. His Virology research includes themes of Disease, Drug resistance and Genotype.

His work investigates the relationship between Genome and topics such as Botany that intersect with problems in Neofunctionalization. His work carried out in the field of Pyrosequencing brings together such families of science as Sanger sequencing, Molecular biology, Genotyping and Deep sequencing. His Computational biology research is multidisciplinary, incorporating elements of Combinatorial chemistry and Nucleic acid.

Between 2007 and 2018, his most popular works were:

  • A core gut microbiome in obese and lean twins (5272 citations)
  • A Draft Sequence of the Neandertal Genome (2666 citations)
  • The tomato genome sequence provides insights into fleshy fruit evolution (1991 citations)

In his most recent research, the most cited papers focused on:

  • DNA
  • Gene
  • Genome

Michael Egholm focuses on Genetics, Genome, Sequence analysis, DNA sequencing and Virology. Genetics and Gut flora are commonly linked in his work. He focuses mostly in the field of Genome, narrowing it down to topics relating to Botany and, in certain cases, Neofunctionalization.

Michael Egholm has included themes like Candidate gene, Linkage disequilibrium, IFIH1 Gene and Exon in his Sequence analysis study. The DNA sequencing study which covers Gene rearrangement that intersects with Immune receptor, Genomic library, Amplicon and Immune system. His study in the field of Virus and Viral disease also crosses realms of Arenavirus.

Best Publications

  • Genome sequencing in microfabricated high-density picolitre reactors

    Marcel Margulies;Michael Egholm;William E Altman;Said Attiya

  • A core gut microbiome in obese and lean twins

    Peter J. Turnbaugh;Micah Hamady;Tanya Yatsunenko;Brandi L. Cantarel

  • A Draft Sequence of the Neandertal Genome

    Richard E. Green;Johannes Krause;Adrian W. Briggs;Tomislav Maricic

  • Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide

    Peter E. Nielsen;Michael Egholm;Rolf H. Berg;Ole Buchardt

  • The tomato genome sequence provides insights into fleshy fruit evolution

    Shusei Sato;Satoshi Tabata;Hideki Hirakawa;Erika Asamizu

  • The genome of the domesticated apple ( Malus × domestica Borkh.)

    Riccardo Velasco;Andrey Zharkikh;Jason Affourtit;Amit Dhingra

  • The complete genome of an individual by massively parallel DNA sequencing

    David A. Wheeler;Maithreyan Srinivasan;Michael Egholm;Yufeng Shen

  • A Metagenomic Survey of Microbes in Honey Bee Colony Collapse Disorder

    Diana L. Cox-Foster;Sean Conlan;Edward C. Holmes;Edward C. Holmes;Gustavo Palacios

  • Peptide nucleic acids

    Ole Buchardt;Michael Egholm;Peter Eigil Prof. Dr. Nielsen;Rolf Hendrik Berg

  • Comprehensive human genome amplification using multiple displacement amplification

    Frank B. Dean;Seiyu Hosono;Linhua Fang;Xiaohong Wu

  • Paired-end mapping reveals extensive structural variation in the human genome.

    Jan O. Korbel;Alexander Eckehart Urban;Jason P. Affourtit;Brian Godwin

  • Peptide nucleic acids (PNA) : oligonucleotide analogues with an achiral peptide backbone

    Michael Egholm;Ole Buchardt;Peter E. Nielsen;Rolf H. Berg

  • Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes.

    Sergey Nejentsev;Neil Walker;David Riches;Michael Egholm

  • Analysis of one million base pairs of Neanderthal DNA

    Richard E. Green;Johannes Krause;Susan E. Ptak;Adrian W. Briggs

  • Stability of peptide nucleic acids in human serum and cellular extracts

    Vadim V. Demidov;Vadim V. Demidov;Vladimir N. Potaman;M.D. Frank-Kamenetskil;Michael Egholm

  • A new arenavirus in a cluster of fatal transplant-associated diseases.

    Gustavo F. Palacios;Julian Druce;Lei Du;Thomas Tran

  • Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility

    Peter E. Nielsen;Michael Egholm;Rolf H. Berg;Ole Buchardt

  • A complete Neandertal mitochondrial genome sequence determined by high-throughput sequencing

    Richard E. Green;Anna-Sapfo Malaspinas;Johannes Krause;Adrian W. Briggs

  • Peptide nucleic acids having amino acid side chains

    Ole Buchardt;Michael Egholm;Peter Eigil Nielsen

  • DNA-like double helix formed by peptide nucleic acid

    Pernilla Wittung;Peter E. Nielsen;Ole Buchardt;Michael Egholm

Frequent Co-Authors

Peter E. Nielsen
Peter E. Nielsen University of Copenhagen
Ole Buchardt
Ole Buchardt University of Copenhagen
W. Ian Lipkin
W. Ian Lipkin Columbia University
Gustavo Palacios
Gustavo Palacios Icahn School of Medicine at Mount Sinai
Thomas Briese
Thomas Briese Columbia University
David J. Ecker
David J. Ecker Ionis Pharmaceuticals (United States)
Roger S. Lasken
Roger S. Lasken J. Craig Venter Institute
Richard E. Green
Richard E. Green University of California, Santa Cruz
Svante Pääbo
Svante Pääbo Max Planck Institute for Evolutionary Anthropology
Johannes Krause
Johannes Krause Max Planck Society

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