World's Best Scientists 2026 revealed!
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Makoto Otsuka

Makoto Otsuka

Musashino University
Japan

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Chemistry 60 9912 8966 710 652 347 10201

Makoto Otsuka publications per year

The chart shows the history of publications by Makoto Otsuka between 1982 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Makoto Otsuka published across 44 years, from 1982 to 2025, averaging 9.8 papers a year. Output peaked at 22 publications in 2013. 19 of the 433 publications appeared in the last two years.

No. of publications
5 10 15 20
Bar chart. Horizontal axis: year, 1982 to 2025. Vertical axis: number of publications, 0 to 22. Peak 22 publications in 2013. 1982: 3 publications 1983: 3 publications 1984: 6 publications 1985: 4 publications 1986: 4 publications 1987: 2 publications 1988: 3 publications 1989: 5 publications 1990: 4 publications 1991: 3 publications 1992: 10 publications 1993: 9 publications 1994: 20 publications 1995: 11 publications 1996: 11 publications 1997: 5 publications 1998: 3 publications 1999: 12 publications 2000: 10 publications 2001: 5 publications 2002: 7 publications 2003: 3 publications 2004: 16 publications 2005: 12 publications 2006: 14 publications 2007: 9 publications 2008: 5 publications 2009: 11 publications 2010: 18 publications 2011: 17 publications 2012: 20 publications 2013: 22 publications 2014: 12 publications 2015: 11 publications 2016: 16 publications 2017: 17 publications 2018: 18 publications 2019: 9 publications 2020: 16 publications 2021: 11 publications 2022: 11 publications 2023: 6 publications 2024: 10 publications 2025: 9 publications
1982 2025

433 publications in total across all disciplines

View publications per year as a table
Makoto Otsuka: publications per year, 1982 to 2025
Year Publications
1982 3
1983 3
1984 6
1985 4
1986 4
1987 2
1988 3
1989 5
1990 4
1991 3
1992 10
1993 9
1994 20
1995 11
1996 11
1997 5
1998 3
1999 12
2000 10
2001 5
2002 7
2003 3
2004 16
2005 12
2006 14
2007 9
2008 5
2009 11
2010 18
2011 17
2012 20
2013 22
2014 12
2015 11
2016 16
2017 17
2018 18
2019 9
2020 16
2021 11
2022 11
2023 6
2024 10
2025 9
Total 433
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Makoto Otsuka publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Makoto Otsuka sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 63 bars. Horizontal axis: publications, 61–80 to 1,295+. Vertical axis: number of scientists, 0 to 1,350. Most scientists, 1,350, have 161–180 publications. The last bar groups every scientist with 1,295 publications or more. The highlighted bar, 341–360 publications, is where this scientist sits. 61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61–80 publications 1,295+

This scientist: 347 publications — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

View publications distribution as a table
Number of Chemistry scientists by publication count, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
Publications Scientists This scientist
61–80 66
81–100 302
101–120 623
121–140 918
141–160 1,218
161–180 1,350
181–200 1,344
201–220 1,281
221–240 1,216
241–260 1,100
261–280 979
281–300 939
301–320 764
321–340 643
341–360 628 347
361–380 522
381–400 459
401–420 397
421–440 327
441–460 270
461–480 265
481–500 252
501–520 201
521–540 185
541–560 148
561–580 148
581–600 132
601–620 114
621–640 104
641–660 91
661–680 92
681–700 73
701–720 57
721–740 54
741–760 67
761–780 45
781–800 46
801–820 39
821–840 32
841–860 36
861–880 29
881–900 26
901–920 24
921–940 14
941–960 23
961–980 28
981–1,000 15
1,001–1,020 29
1,021–1,040 12
1,041–1,060 19
1,061–1,080 12
1,081–1,100 6
1,101–1,120 8
1,121–1,140 12
1,141–1,160 5
1,161–1,180 6
1,181–1,200 14
1,201–1,220 7
1,221–1,240 2
1,241–1,260 6
1,261–1,280 4
1,281–1,294 6
1,295+ 100
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Makoto Otsuka D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Makoto Otsuka sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 61 bars. Horizontal axis: D-Index, 40–41 to 159+. Vertical axis: number of scientists, 0 to 1,051. Most scientists, 1,051, have 56–57 D-Index. The last bar groups every scientist with 159 D-Index or more. The highlighted bar, 60–61 D-Index, is where this scientist sits. 40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40–41 D-Index 159+

This scientist: 60 D-Index — 47th percentile

47% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

View D-Index distribution as a table
Number of Chemistry scientists by D-index, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
D-Index Scientists This scientist
40–41 289
42–43 612
44–45 808
46–47 776
48–49 835
50–51 861
52–53 872
54–55 933
56–57 1,051
58–59 930
60–61 882 60
62–63 834
64–65 731
66–67 775
68–69 683
70–71 646
72–73 561
74–75 501
76–77 437
78–79 388
80–81 354
82–83 292
84–85 275
86–87 254
88–89 235
90–91 185
92–93 192
94–95 155
96–97 163
98–99 125
100–101 105
102–103 105
104–105 112
106–107 88
108–109 68
110–111 69
112–113 65
114–115 79
116–117 61
118–119 44
120–121 37
122–123 40
124–125 33
126–127 26
128–129 34
130–131 35
132–133 25
134–135 27
136–137 17
138–139 16
140–141 20
142–143 20
144–145 15
146–147 9
148–149 9
150–151 16
152–153 11
154–155 9
156–157 3
158 3
159+ 98
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Overview

Makoto Otsuka is affiliated with Musashino University in Japan. Their research contributions primarily lie within the fields of Chemistry and Medicine, with a strong focus on subfields including Analytical Chemistry, Pharmaceutical Science, Biophysics, Food Science, and Materials Chemistry.

Their research topics emphasize Spectroscopy and Chemometric Analyses, Drug Solubility and Delivery Systems, and Spectroscopy Techniques in Biomedical and Chemical Research. Additional areas of focus include Crystallization and Solubility Studies, Microencapsulation and Drying Processes, Bone Tissue Engineering Materials, and Analytical Methods in Pharmaceuticals.

Among the recent papers authored or co-authored by Makoto Otsuka are the following:

  • Application of spray freeze drying to theophylline-oxalic acid cocrystal engineering for inhaled dry powder technology, 2020, Drug Development and Industrial Pharmacy
  • Enhancement of mineralization on porous titanium surface by filling with nano-hydroxyapatite particles fabricated with a vacuum spray method, 2020, Materials Science and Engineering C
  • Complete Cocrystal Formation during Resonant Acoustic Wet Granulation: Effect of Granulation Liquids, 2021, Pharmaceutics
  • Cocrystal Formation through Solid-State Reaction between Ibuprofen and Nicotinamide Revealed Using THz and IR Spectroscopy with Multivariate Analysis, 2020, Crystals
  • Comparative study on the real-time monitoring of a fluid bed drying process of extruded granules using near-infrared spectroscopy and audible acoustic emission, 2022, International Journal of Pharmaceutics

Frequent coauthors collaborating with Makoto Otsuka include Tetsuo Sasaki, Yusuke Hattori, Keita Koyanagi, Akinori Ueno, and Tomoaki Sakamoto.

Makoto Otsuka's publications appear in several notable academic venues, with repeated contributions in:

  • Journal of Drug Delivery Science and Technology
  • SSRN Electronic Journal
  • Pharmaceutics
  • Colloids and Surfaces A Physicochemical and Engineering Aspects
  • Drug Development and Industrial Pharmacy

Best Publications

  • Zinc-releasing calcium phosphate for stimulating bone formation ☆

    Atsuo Ito;Haruo Kawamura;Makoto Otsuka;Masako Ikeuchi

  • Relationships among carbonated apatite solubility, crystallite size, and microstrain parameters.

    A. A. Baig;J. L. Fox;R. A. Young;Z. Wang

  • Physicochemical characterization of indomethacin polymorphs and the transformation kinetics in ethanol.

    Nobuyoshi Kaneniwa;Makoto Otsuka;Tetsuo Hayashi

  • Self-setting hydroxyapatite cement: a novel skeletal drug-delivery system for antibiotics.

    Duncan Yu;Joseph Wong;Yoshihisa Matsuda;Jeffrey L. Fox

  • Zinc-containing tricalcium phosphate and related materials for promoting bone formation

    Atsuo Ito;Makoto Otsuka;Haruo Kawamura;Masako Ikeuchi

  • Sustained release chemical substance carrier and method for manufacturing therefor

    Matsushima Asako;Nakasu Masanori;Otsuka Makoto

  • A self‐setting TTCP‐DCPD apatite cement for release of vancomycin

    Chiaki Hamanishi;Katsunori Kitamoto;Seisuke Tanaka;Makoto Otsuka

  • Comparative particle size determination of phenacetin bulk powder by using Kubelka–Munk theory and principal component regression analysis based on near-infrared spectroscopy

    Makoto Otsuka

  • Dissolution process analysis using model-free Noyes-Whitney integral equation.

    Yusuke Hattori;Yoshimasa Haruna;Makoto Otsuka

  • Combined Effects of Laser Irradiation and Chemical Inhibitors on the Dissolution of Dental Enamel

    J.L. Fox;D. Yu;M. Otsuka;W.I. Higuchi

  • Effect of environmental temperature on polymorphic solid-state transformation of indomethacin during grinding

    Makoto Otsuka;Takahiro Matsumoto;Nobuyoshi Kaneniwa

  • Initial Dissolution Rate Studies on Dental Enamel after CO2 Laser Irradiation

    J.L. Fox;D. Yu;M. Otsuka;W.I. Higuchi

  • Infrared spectroscopic study of lipid interaction in stratum corneum treated with transdermal absorption enhancers

    Yasuko Obata;Shunichi Utsumi;Hiroshi Watanabe;Masafumi Suda

  • A novel skeletal drug-delivery system using self-setting calcium phosphate cement. 3. Physicochemical properties and drug-release rate of bovine insulin and bovine albumin

    Makoto Otsuka;Yoshihisa Matsuda;Yoshiko Suwa;Jeffrey L. Fox

  • A novel skeletal drug delivery system for anti-bacterial drugs using self-setting hydroxyapatite cement.

    M. Otsuka;Y. Matsuda;D. Yu;J. Wong

  • A Novel Skeletal Drug Delivery System Using a Self‐Setting Calcium Phosphate Cement. 5 Drug Release Behavior from a Heterogeneous Drug-Loaded Cement Containing an Anticancer Drug

    Makoto Otsuka;Yoshihisa Matsuda;Yoshiko Suwa;Jeffrey L. Fox

  • Effect of carbonate content and crystallinity on the metastable equilibrium solubility behavior of carbonated apatites

    Arif A. Baig;Jeffrey L. Fox;Jer Hsu;Zeren Wang

  • Effect of Polymorphic Forms of Bullk Powders on Pharmaceutical Properties of Carbamazepine Granules

    Makoto Otsuka;Hitoshi Hasegawa;Yoshihisa Matsuda

  • A kinetic study of the crystallization process of noncrystalline indomethacin under isothermal conditions.

    Makoto Otsuka;Nobuyoshi Kaneniwa

  • Hygroscopicity of carbamazepine crystalline powders

    Nobuyoshi Kaneniwa;Tetsuo Yamaguchi;Nobutoshi Watari;Makoto Otsuka

  • Combined effects of laser irradiation/solution fluoride ion on enamel demineralization.

    J. Hsu;J.L. Fox;Z. Wang;G.L. Powell

Frequent Co-Authors

William I. Higuchi
William I. Higuchi University of Utah
Atsuo Ito
Atsuo Ito National Institute of Advanced Industrial Science and Technology
Yukihiro Ozaki
Yukihiro Ozaki Kwansei Gakuin University
Takashi Nakamura
Takashi Nakamura Kyoto University
Tadashi Kokubo
Tadashi Kokubo Chubu University
Hiroyuki Ohshima
Hiroyuki Ohshima Tokyo University of Science
Yuichi Sugiyama
Yuichi Sugiyama University of Tokyo
Kozo Takayama
Kozo Takayama Josai University
Hajime Ohgushi
Hajime Ohgushi National Institute of Advanced Industrial Science and Technology
David W. Green
David W. Green University College London

External Links

Personal website of Makoto Otsuka

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