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Makoto Otsuka

Makoto Otsuka

D-Index & Metrics

Chemistry

D-Index
60
Citations
10201
World Ranking
9914
National Ranking
710

Overview

Makoto Otsuka is affiliated with Musashino University in Japan. Their research contributions primarily lie within the fields of Chemistry and Medicine, with a strong focus on subfields including Analytical Chemistry, Pharmaceutical Science, Biophysics, Food Science, and Materials Chemistry.

Their research topics emphasize Spectroscopy and Chemometric Analyses, Drug Solubility and Delivery Systems, and Spectroscopy Techniques in Biomedical and Chemical Research. Additional areas of focus include Crystallization and Solubility Studies, Microencapsulation and Drying Processes, Bone Tissue Engineering Materials, and Analytical Methods in Pharmaceuticals.

Among the recent papers authored or co-authored by Makoto Otsuka are the following:

  • Application of spray freeze drying to theophylline-oxalic acid cocrystal engineering for inhaled dry powder technology, 2020, Drug Development and Industrial Pharmacy
  • Enhancement of mineralization on porous titanium surface by filling with nano-hydroxyapatite particles fabricated with a vacuum spray method, 2020, Materials Science and Engineering C
  • Complete Cocrystal Formation during Resonant Acoustic Wet Granulation: Effect of Granulation Liquids, 2021, Pharmaceutics
  • Cocrystal Formation through Solid-State Reaction between Ibuprofen and Nicotinamide Revealed Using THz and IR Spectroscopy with Multivariate Analysis, 2020, Crystals
  • Comparative study on the real-time monitoring of a fluid bed drying process of extruded granules using near-infrared spectroscopy and audible acoustic emission, 2022, International Journal of Pharmaceutics

Frequent coauthors collaborating with Makoto Otsuka include Tetsuo Sasaki, Yusuke Hattori, Keita Koyanagi, Akinori Ueno, and Tomoaki Sakamoto.

Makoto Otsuka's publications appear in several notable academic venues, with repeated contributions in:

  • Journal of Drug Delivery Science and Technology
  • SSRN Electronic Journal
  • Pharmaceutics
  • Colloids and Surfaces A Physicochemical and Engineering Aspects
  • Drug Development and Industrial Pharmacy

Best Publications

  • Zinc-releasing calcium phosphate for stimulating bone formation ☆

    Atsuo Ito;Haruo Kawamura;Makoto Otsuka;Masako Ikeuchi

  • Relationships among carbonated apatite solubility, crystallite size, and microstrain parameters.

    A. A. Baig;J. L. Fox;R. A. Young;Z. Wang

  • Physicochemical characterization of indomethacin polymorphs and the transformation kinetics in ethanol.

    Nobuyoshi Kaneniwa;Makoto Otsuka;Tetsuo Hayashi

  • Self-setting hydroxyapatite cement: a novel skeletal drug-delivery system for antibiotics.

    Duncan Yu;Joseph Wong;Yoshihisa Matsuda;Jeffrey L. Fox

  • Zinc-containing tricalcium phosphate and related materials for promoting bone formation

    Atsuo Ito;Makoto Otsuka;Haruo Kawamura;Masako Ikeuchi

  • Sustained release chemical substance carrier and method for manufacturing therefor

    Matsushima Asako;Nakasu Masanori;Otsuka Makoto

  • A self‐setting TTCP‐DCPD apatite cement for release of vancomycin

    Chiaki Hamanishi;Katsunori Kitamoto;Seisuke Tanaka;Makoto Otsuka

  • Comparative particle size determination of phenacetin bulk powder by using Kubelka–Munk theory and principal component regression analysis based on near-infrared spectroscopy

    Makoto Otsuka

  • Dissolution process analysis using model-free Noyes-Whitney integral equation.

    Yusuke Hattori;Yoshimasa Haruna;Makoto Otsuka

  • Combined Effects of Laser Irradiation and Chemical Inhibitors on the Dissolution of Dental Enamel

    J.L. Fox;D. Yu;M. Otsuka;W.I. Higuchi

  • Effect of environmental temperature on polymorphic solid-state transformation of indomethacin during grinding

    Makoto Otsuka;Takahiro Matsumoto;Nobuyoshi Kaneniwa

  • Initial Dissolution Rate Studies on Dental Enamel after CO2 Laser Irradiation

    J.L. Fox;D. Yu;M. Otsuka;W.I. Higuchi

  • Infrared spectroscopic study of lipid interaction in stratum corneum treated with transdermal absorption enhancers

    Yasuko Obata;Shunichi Utsumi;Hiroshi Watanabe;Masafumi Suda

  • A novel skeletal drug-delivery system using self-setting calcium phosphate cement. 3. Physicochemical properties and drug-release rate of bovine insulin and bovine albumin

    Makoto Otsuka;Yoshihisa Matsuda;Yoshiko Suwa;Jeffrey L. Fox

  • A novel skeletal drug delivery system for anti-bacterial drugs using self-setting hydroxyapatite cement.

    M. Otsuka;Y. Matsuda;D. Yu;J. Wong

  • A Novel Skeletal Drug Delivery System Using a Self‐Setting Calcium Phosphate Cement. 5 Drug Release Behavior from a Heterogeneous Drug-Loaded Cement Containing an Anticancer Drug

    Makoto Otsuka;Yoshihisa Matsuda;Yoshiko Suwa;Jeffrey L. Fox

  • Effect of carbonate content and crystallinity on the metastable equilibrium solubility behavior of carbonated apatites

    Arif A. Baig;Jeffrey L. Fox;Jer Hsu;Zeren Wang

  • Effect of Polymorphic Forms of Bullk Powders on Pharmaceutical Properties of Carbamazepine Granules

    Makoto Otsuka;Hitoshi Hasegawa;Yoshihisa Matsuda

  • A kinetic study of the crystallization process of noncrystalline indomethacin under isothermal conditions.

    Makoto Otsuka;Nobuyoshi Kaneniwa

  • Hygroscopicity of carbamazepine crystalline powders

    Nobuyoshi Kaneniwa;Tetsuo Yamaguchi;Nobutoshi Watari;Makoto Otsuka

  • Combined effects of laser irradiation/solution fluoride ion on enamel demineralization.

    J. Hsu;J.L. Fox;Z. Wang;G.L. Powell

Frequent Co-Authors

William I. Higuchi
William I. Higuchi University of Utah
Atsuo Ito
Atsuo Ito National Institute of Advanced Industrial Science and Technology
Yukihiro Ozaki
Yukihiro Ozaki Kwansei Gakuin University
Takashi Nakamura
Takashi Nakamura Kyoto University
Tadashi Kokubo
Tadashi Kokubo Chubu University
Hiroyuki Ohshima
Hiroyuki Ohshima Tokyo University of Science
Yuichi Sugiyama
Yuichi Sugiyama University of Tokyo
Kozo Takayama
Kozo Takayama Josai University
Hajime Ohgushi
Hajime Ohgushi National Institute of Advanced Industrial Science and Technology
David W. Green
David W. Green University College London

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