World's Best Scientists 2026 revealed!
Makoto Otsuka

Makoto Otsuka

D-Index & Metrics

Chemistry

D-Index
60
Citations
10201
World Ranking
9912
National Ranking
710

Makoto Otsuka publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Makoto Otsuka sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 347 publications — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Makoto Otsuka D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Makoto Otsuka sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 60 D-Index — 47th percentile

47% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Makoto Otsuka is affiliated with Musashino University in Japan. Their research contributions primarily lie within the fields of Chemistry and Medicine, with a strong focus on subfields including Analytical Chemistry, Pharmaceutical Science, Biophysics, Food Science, and Materials Chemistry.

Their research topics emphasize Spectroscopy and Chemometric Analyses, Drug Solubility and Delivery Systems, and Spectroscopy Techniques in Biomedical and Chemical Research. Additional areas of focus include Crystallization and Solubility Studies, Microencapsulation and Drying Processes, Bone Tissue Engineering Materials, and Analytical Methods in Pharmaceuticals.

Among the recent papers authored or co-authored by Makoto Otsuka are the following:

  • Application of spray freeze drying to theophylline-oxalic acid cocrystal engineering for inhaled dry powder technology, 2020, Drug Development and Industrial Pharmacy
  • Enhancement of mineralization on porous titanium surface by filling with nano-hydroxyapatite particles fabricated with a vacuum spray method, 2020, Materials Science and Engineering C
  • Complete Cocrystal Formation during Resonant Acoustic Wet Granulation: Effect of Granulation Liquids, 2021, Pharmaceutics
  • Cocrystal Formation through Solid-State Reaction between Ibuprofen and Nicotinamide Revealed Using THz and IR Spectroscopy with Multivariate Analysis, 2020, Crystals
  • Comparative study on the real-time monitoring of a fluid bed drying process of extruded granules using near-infrared spectroscopy and audible acoustic emission, 2022, International Journal of Pharmaceutics

Frequent coauthors collaborating with Makoto Otsuka include Tetsuo Sasaki, Yusuke Hattori, Keita Koyanagi, Akinori Ueno, and Tomoaki Sakamoto.

Makoto Otsuka's publications appear in several notable academic venues, with repeated contributions in:

  • Journal of Drug Delivery Science and Technology
  • SSRN Electronic Journal
  • Pharmaceutics
  • Colloids and Surfaces A Physicochemical and Engineering Aspects
  • Drug Development and Industrial Pharmacy

Best Publications

  • Zinc-releasing calcium phosphate for stimulating bone formation ☆

    Atsuo Ito;Haruo Kawamura;Makoto Otsuka;Masako Ikeuchi

  • Relationships among carbonated apatite solubility, crystallite size, and microstrain parameters.

    A. A. Baig;J. L. Fox;R. A. Young;Z. Wang

  • Physicochemical characterization of indomethacin polymorphs and the transformation kinetics in ethanol.

    Nobuyoshi Kaneniwa;Makoto Otsuka;Tetsuo Hayashi

  • Self-setting hydroxyapatite cement: a novel skeletal drug-delivery system for antibiotics.

    Duncan Yu;Joseph Wong;Yoshihisa Matsuda;Jeffrey L. Fox

  • Zinc-containing tricalcium phosphate and related materials for promoting bone formation

    Atsuo Ito;Makoto Otsuka;Haruo Kawamura;Masako Ikeuchi

  • Sustained release chemical substance carrier and method for manufacturing therefor

    Matsushima Asako;Nakasu Masanori;Otsuka Makoto

  • A self‐setting TTCP‐DCPD apatite cement for release of vancomycin

    Chiaki Hamanishi;Katsunori Kitamoto;Seisuke Tanaka;Makoto Otsuka

  • Comparative particle size determination of phenacetin bulk powder by using Kubelka–Munk theory and principal component regression analysis based on near-infrared spectroscopy

    Makoto Otsuka

  • Dissolution process analysis using model-free Noyes-Whitney integral equation.

    Yusuke Hattori;Yoshimasa Haruna;Makoto Otsuka

  • Combined Effects of Laser Irradiation and Chemical Inhibitors on the Dissolution of Dental Enamel

    J.L. Fox;D. Yu;M. Otsuka;W.I. Higuchi

  • Effect of environmental temperature on polymorphic solid-state transformation of indomethacin during grinding

    Makoto Otsuka;Takahiro Matsumoto;Nobuyoshi Kaneniwa

  • Initial Dissolution Rate Studies on Dental Enamel after CO2 Laser Irradiation

    J.L. Fox;D. Yu;M. Otsuka;W.I. Higuchi

  • Infrared spectroscopic study of lipid interaction in stratum corneum treated with transdermal absorption enhancers

    Yasuko Obata;Shunichi Utsumi;Hiroshi Watanabe;Masafumi Suda

  • A novel skeletal drug-delivery system using self-setting calcium phosphate cement. 3. Physicochemical properties and drug-release rate of bovine insulin and bovine albumin

    Makoto Otsuka;Yoshihisa Matsuda;Yoshiko Suwa;Jeffrey L. Fox

  • A novel skeletal drug delivery system for anti-bacterial drugs using self-setting hydroxyapatite cement.

    M. Otsuka;Y. Matsuda;D. Yu;J. Wong

  • A Novel Skeletal Drug Delivery System Using a Self‐Setting Calcium Phosphate Cement. 5 Drug Release Behavior from a Heterogeneous Drug-Loaded Cement Containing an Anticancer Drug

    Makoto Otsuka;Yoshihisa Matsuda;Yoshiko Suwa;Jeffrey L. Fox

  • Effect of carbonate content and crystallinity on the metastable equilibrium solubility behavior of carbonated apatites

    Arif A. Baig;Jeffrey L. Fox;Jer Hsu;Zeren Wang

  • Effect of Polymorphic Forms of Bullk Powders on Pharmaceutical Properties of Carbamazepine Granules

    Makoto Otsuka;Hitoshi Hasegawa;Yoshihisa Matsuda

  • A kinetic study of the crystallization process of noncrystalline indomethacin under isothermal conditions.

    Makoto Otsuka;Nobuyoshi Kaneniwa

  • Hygroscopicity of carbamazepine crystalline powders

    Nobuyoshi Kaneniwa;Tetsuo Yamaguchi;Nobutoshi Watari;Makoto Otsuka

  • Combined effects of laser irradiation/solution fluoride ion on enamel demineralization.

    J. Hsu;J.L. Fox;Z. Wang;G.L. Powell

Frequent Co-Authors

William I. Higuchi
William I. Higuchi University of Utah
Atsuo Ito
Atsuo Ito National Institute of Advanced Industrial Science and Technology
Yukihiro Ozaki
Yukihiro Ozaki Kwansei Gakuin University
Takashi Nakamura
Takashi Nakamura Kyoto University
Tadashi Kokubo
Tadashi Kokubo Chubu University
Hiroyuki Ohshima
Hiroyuki Ohshima Tokyo University of Science
Yuichi Sugiyama
Yuichi Sugiyama University of Tokyo
Kozo Takayama
Kozo Takayama Josai University
Hajime Ohgushi
Hajime Ohgushi National Institute of Advanced Industrial Science and Technology
David W. Green
David W. Green University College London

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