World's Best Scientists 2026 revealed!
John M. Pawelek

John M. Pawelek

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
23746
World Ranking
8962
National Ranking
3980

Overview

John M. Pawelek was affiliated with Yale University in the United States. Their research primarily focused on areas within Biochemistry, Genetics and Molecular Biology, and Medicine. The subfields they contributed to included Molecular Biology, Oncology, Cancer Research, Biotechnology, and Immunology.

The scientific topics covered in their work involved:

  • Cancer Cells and Metastasis
  • Cancer Research and Treatments
  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation
  • Histone Deacetylase Inhibitors Research
  • Metabolism, Diabetes, and Cancer
  • Cutaneous Melanoma Detection and Management

Pawelek's research was published in a variety of journals, including World Journal of Clinical Oncology, BMC Cancer, Cancer Genetics, Cancer Letters, and SN Comprehensive Clinical Medicine.

Recent papers authored or coauthored by Pawelek included:

  • Roles of cell fusion, hybridization and polyploid cell formation in cancer metastasis (2020) - World Journal of Clinical Oncology
  • Restricting tumor lactic acid metabolism using dichloroacetate improves T cell functions (2022) - BMC Cancer
  • A metabolic switch to memory CAR T cells: Implications for cancer treatment (2020) - Cancer Letters
  • A melanoma patient with macrophage-cancer cell hybrids in the primary tumor, a lymph node metastasis and a brain metastasis (2021) - Cancer Genetics
  • International Scientific Collaboration Is Needed to Bridge Science to Society: USERN2020 Consensus Statement (2021) - SN Comprehensive Clinical Medicine

Frequent coauthors who collaborated with John M. Pawelek included Hosein Rostamian, Keyvan Fallah-Mehrjardi, Hamid Reza Mirzaei, Jamshid Hadjati, and Mohammad Khakpoor-Koosheh.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Mammalian tyrosinase catalyzes three reactions in the biosynthesis of melanin

    Ann Körner;John Pawelek

  • Tumor-targeted Salmonella as a novel anticancer vector.

    J M Pawelek;K B Low;D Bermudes

  • Lipid A mutant Salmonella with suppressed virulence and TNFalpha induction retain tumor-targeting in vivo

    K. B. Low;M. Ittensohn;T. Le;J. Platt

  • Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma

    Xiao Hong Ma;Sheng Fu Piao;Souvik Dey;Quentin McAfee

  • L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functions.

    Andrzej Slominski;Michal A. Zmijewski;John Pawelek

  • Fusion of tumour cells with bone marrow-derived cells: a unifying explanation for metastasis.

    John M. Pawelek;Ashok K. Chakraborty

  • Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B

    Ashok K. Chakraborty;Yoko Funasaka;Andrzej Slominski;Gennady Ermak

  • Bacteria as tumour-targeting vectors.

    John M Pawelek;K Brooks Low;David Bermudes

  • Biodistribution and Genetic Stability of the Novel Antitumor Agent VNP20009, a Genetically Modified Strain of Salmonella typhimuvium

    C. Clairmont;K. C. Lee;J. Pike;M. Ittensohn

  • Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis and poor outcome.

    Rossitza Lazova;Robert L. Camp;Vincent Klump;Summar F. Siddiqui

  • New regulators of melanin biosynthesis and the autodestruction of melanoma cells

    John Pawelek;Ann Körner;Alan Bergstrom;Jean Bologna

  • Factors regulating growth and pigmentation of melanoma cells.

    John M. Pawelek

  • Curcumin: A new candidate for melanoma therapy?

    Hamed Mirzaei;Gholamreza Naseri;Ramin Rezaee;Mohsen Mohammadi

  • 5,6-DIHYDROXYINDOLE IS A MELANIN PRECURSOR SHOWING POTENT CYTOTOXICITY

    J. M. Pawelek;A. B. Lerner

  • Dopachrome Conversion: A Possible Control Point in Melanin Biosynthesis

    Ann M. Körner;John Pawelek

  • The biosynthesis of mammalian melanin.

    John M. Pawelek;Ann M. Körner

  • Melanocyte-stimulating hormone promotes activation of pre-existing tyrosinase molecules in cloudman s91 melanoma cells.

    Glenda Wong;John Pawelek

  • The cancer cell--leukocyte fusion theory of metastasis.

    John M Pawelek;Ashok K Chakraborty

  • Positive regulation of melanin pigmentation by two key substrates of the melanogenic pathway, L-tyrosine and L-dopa.

    A. Slominski;G. Moellmann;E. Kuklinska;A. Bomirski

Frequent Co-Authors

Seth J. Orlow
Seth J. Orlow New York University
Andrzej Slominski
Andrzej Slominski University of Alabama at Birmingham
Ravi K. Amaravadi
Ravi K. Amaravadi University of Pennsylvania
David L. Rimm
David L. Rimm Yale University
Nima Rezaei
Nima Rezaei Tehran University of Medical Sciences
Douglas E. Brash
Douglas E. Brash Yale University
Vincent J. Hearing
Vincent J. Hearing National Institutes of Health
Ruth Halaban
Ruth Halaban Yale University
Masamitsu Ichihashi
Masamitsu Ichihashi Kobe University
Enza Maria Valente
Enza Maria Valente University of Pavia

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

As demand surges for health professionals with expertise in biology and biochemistry, flexible online degrees now provide more ways than ever to advance your education and career. If you’re interested in nutrition, pursuing an online nutrition degree can prepare you for roles in wellness coaching, public health, or food science.

For those seeking leadership roles in healthcare, take note of the increasing number of cahme accredited mha programs that are available online. These programs provide advanced skills in management and policy, helping graduates move into key administrative positions.

Nursing professionals can further their qualifications through accredited online dnp programs, many of which no longer require clinical hours, making them accessible for working nurses.

Those aiming for the highest academic and executive careers might pursue advanced doctoral programs for healthcare administration offered through distance learning. These online pathways are ideal for ambitious professionals seeking flexibility alongside career advancement in the health sciences sector.

Best Scientists Citing John M. Pawelek