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Biology and Biochemistry

D-Index
58
Citations
11715
World Ranking
13210
National Ranking
5627

Overview

John F. Kelly is affiliated with the National Academies of Sciences, Engineering, and Medicine in the United States. Their research output spans multiple areas within biochemistry, molecular biology, and medicine, with a notable focus on glycosylation, antibody research, and infectious diseases.

Kelly's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their work further delves into subfields such as:

  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging
  • Organic Chemistry
  • Ecology
  • Epidemiology

Major topics covered in their publications are:

  • Monoclonal and Polyclonal Antibodies Research
  • Glycosylation and Glycoproteins Research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Genomics and Phylogenetic Studies
  • Protein purification and stability
  • Bacteriophages and microbial interactions
  • Mycobacterium research and diagnosis

Kelly's research has been published in a variety of journals, including frequent publications in:

  • Biotechnology and Bioengineering
  • Glycobiology
  • Journal of Biological Chemistry
  • mAbs
  • Scientific Reports

Among recent papers authored or co-authored by Kelly are:

  • "A CHO stable pool production platform for rapid clinical development of trimeric SARS-CoV-2 spike subunit vaccine antigens" (2023), published in Biotechnology and Bioengineering
  • "Defining the epitope of a blood-brain barrier crossing single domain antibody specific for the type 1 insulin-like growth factor receptor" (2021), published in Scientific Reports
  • "Virion glycosylation influences mycobacteriophage immune recognition" (2023), published in Cell Host & Microbe
  • "Identification of a novel N-linked glycan on the archaellins and S-layer protein of the thermophilic methanogen, Methanothermococcus thermolithotrophicus" (2020), published in Journal of Biological Chemistry
  • "Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells" (2023), published in Communications Medicine

Kelly has collaborated multiple times with several researchers, including:

  • Anna Robotham
  • Yves Durocher
  • Janelle Sauvageau
  • Alexandra T. Star
  • Denis Brochu

Best Publications

  • MECHANISM OF INHIBITION OF PROTEIN-TYROSINE PHOSPHATASES BY VANADATE AND PERVANADATE

    Gregory Huyer;Susana Liu;John Kelly;Jason Moffat

  • Caspase 3 activity is required for skeletal muscle differentiation

    Pasan Fernando;John F. Kelly;Kim Balazsi;Ruth S. Slack

  • Structure of the N-Linked Glycan Present on Multiple Glycoproteins in the Gram-negative Bacterium, Campylobacter jejuni

    N. Martin Young;Jean-Robert Brisson;John Kelly;David C. Watson

  • MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons

    Penka S. Petrova;Andrei Raibekas;Jonathan Pevsner;Noel Vigo

  • Identification of the Carbohydrate Moieties and Glycosylation Motifs in Campylobacter jejuni Flagellin

    Pierre Thibault;Susan M. Logan;John F. Kelly;Jean-Robert Brisson

  • Definition of the bacterial N-glycosylation site consensus sequence.

    Michael Kowarik;N Martin Young;Shin Numao;Benjamin L Schulz

  • Changes in flagellin glycosylation affect Campylobacter autoagglutination and virulence.

    Patricia Guerry;Cheryl P. Ewing;Michael Schirm;Maria Lorenzo

  • Proteomic Analysis of Campylobacter jejuni 11168 Biofilms Reveals a Role for the Motility Complex in Biofilm Formation

    Martin Kalmokoff;Patricia Lanthier;Tammy-Lynn Tremblay;Mary Foss

  • Genome-wide expression analyses of Campylobacter jejuni NCTC11168 reveals coordinate regulation of motility and virulence by flhA.

    Catherine D. Carrillo;Eduardo Taboada;John H.E. Nash;Patricia Lanthier

  • Pseudaminic acid, the major modification on Campylobacter flagellin, is synthesized via the Cj1293 gene.

    Scarlett Goon;John F. Kelly;Susan M. Logan;Cheryl P. Ewing

  • Separation and identification of peptides from gel-isolated membrane proteins using a microfabricated device for combined capillary electrophoresis/nanoelectrospray mass spectrometry.

    Jianjun Li;John F. Kelly;Igor Chernushevich;and D. Jed Harrison

  • A Mutant of Francisella tularensis Strain SCHU S4 Lacking the Ability To Express a 58-Kilodalton Protein Is Attenuated for Virulence and Is an Effective Live Vaccine

    Susan Twine;Mona Byström;Wangxue Chen;Mats Forsman

  • Identification of genes involved in the biosynthesis and attachment of Methanococcus voltae N-linked glycans: insight into N-linked glycosylation pathways in Archaea.

    Bonnie Chaban;Sebastien Voisin;John Kelly;Susan M. Logan

  • Comparison of liquid-junction and coaxial interfaces for capillary electrophoresis-mass spectrometry with application to compounds of concern to the aquaculture industry.

    S. Pleasance;P. Thibault;J. Kelly

  • Structural heterogeneity of carbohydrate modifications affects serospecificity of Campylobacter flagellins.

    Susan M. Logan;John F. Kelly;Pierre Thibault;Cheryl P. Ewing

  • Biosynthesis of the N-linked glycan in Campylobacter jejuni and addition onto protein through block transfer.

    John Kelly;Harold Jarrell;Lorna Millar;Luc Tessier

  • Characterization of vascular protein expression patterns in cerebral ischemia/reperfusion using laser capture microdissection and ICAT-nanoLC-MS/MS.

    Arsalan S. Haqqani;Momir Nesic;Ed Preston;Ewa Baumann

  • Identification and Characterization of the Unique N-Linked Glycan Common to the Flagellins and S-layer Glycoprotein of Methanococcus voltae*

    Sebastien Voisin;R. Scott Houliston;John Kelly;Jean-Robert Brisson

  • Capillary Zone Electrophoresis−Electrospray Mass Spectrometry at Submicroliter Flow Rates: Practical Considerations and Analytical Performance

    John F. Kelly;and Louis Ramaley;Pierre Thibault

  • Rapid and sensitive separation of trace level protein digests using microfabricated devices coupled to a quadrupole--time-of-flight mass spectrometer.

    Jianjun Li;Can Wang;John F. Kelly;D. Jed Harrison;D. Jed Harrison

Frequent Co-Authors

Susan M. Logan
Susan M. Logan National Research Council Canada
Pierre Thibault
Pierre Thibault University of Montreal
Ken F. Jarrell
Ken F. Jarrell Queen's University
Jean-Robert Brisson
Jean-Robert Brisson National Research Council Canada
Christine M. Szymanski
Christine M. Szymanski University of Georgia
Evgeny Vinogradov
Evgeny Vinogradov National Research Council Canada
Yves Durocher
Yves Durocher National Academies of Sciences, Engineering, and Medicine
Lori L. Burrows
Lori L. Burrows McMaster University
Danica Stanimirovic
Danica Stanimirovic National Research Council Canada
N. Martin Young
N. Martin Young National Research Council Canada

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