John E. Hyde mainly focuses on Plasmodium falciparum, Genetics, Malaria, Drug resistance and Gene. He mostly deals with Pyrimethamine in his studies of Plasmodium falciparum. His Genetics study integrates concerns from other disciplines, such as DHPS and Dihydropteroate synthase.
His work deals with themes such as Drug and Intensive care medicine, which intersect with Drug resistance. His Gene research integrates issues from Molecular biology and DNA. In his research on the topic of Virology, Chlorproguanil/dapsone, Pyrimethamine-Sulfadoxine and Environmental health is strongly related with Sulfadoxine.
His primary areas of investigation include Plasmodium falciparum, Genetics, Biochemistry, Gene and Malaria. His Plasmodium falciparum research includes elements of Molecular biology, Drug resistance, Dihydrofolate reductase and Virology. His Drug resistance research is multidisciplinary, relying on both Immunology and Intensive care medicine.
His Toxoplasmosis study in the realm of Virology interacts with subjects such as Parasitology. His Genetics study combines topics in areas such as DHPS and Dihydropteroate synthase. His research in Malaria intersects with topics in In vitro, Antigen, Drug and Traditional medicine.
John E. Hyde focuses on Plasmodium falciparum, Biochemistry, Malaria, Drug resistance and Enzyme. John E. Hyde combines Plasmodium falciparum and Symporter in his research. His work on Metabolism, Biosynthesis and ATP synthase as part of general Biochemistry study is frequently linked to Dihydroneopterin aldolase, bridging the gap between disciplines.
His primary area of study in Malaria is in the field of DHPS. His Drug resistance research incorporates elements of Atovaquone, Human parasite, Virology, Immunology and Pharmacology. His Virology study incorporates themes from Pyrimethamine, Sulfadoxine/pyrimethamine, Parasitic disease and Artemisinin.
His primary areas of study are Drug resistance, Malaria, Plasmodium falciparum, Biochemistry and Metabolism. His Drug resistance study combines topics from a wide range of disciplines, such as Biotechnology, Intensive care medicine, Parasitic disease, Artemisinin and Folic Acid Antagonists. His Malaria research is multidisciplinary, incorporating perspectives in Human parasite and Virology.
His work carried out in the field of Plasmodium falciparum brings together such families of science as Genetics, Mutagenesis and Biosynthesis. He specializes in Biochemistry, namely Pyrimidine metabolism. His Metabolism research focuses on Purine metabolism and how it relates to Protozoa, Nucleic acid, Genome, Purine and Metabolic pathway.
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Sequence Variation of the Hydroxymethyldihydropterin Pyrophosphokinase: Dihydropteroate Synthase Gene in Lines of the Human Malaria Parasite, Plasmodium falciparum, with Differing Resistance to Sulfadoxine
Darren R. Brooks;Ping Wang;Martin Read;William M. Watkins.
FEBS Journal (1994)
Pyrimethamine–sulfadoxine resistance in Plasmodium falciparum: what next?
Carol Hopkins Sibley;John E Hyde;Paul F.G Sims;Christopher V Plowe.
Trends in Parasitology (2001)
Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization.
Ping Wang;Martin Read;Paul F. G. Sims;John E. Hyde.
Molecular Microbiology (1997)
Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria
Tony Triglia;Ping Wang;Paul F.G. Sims;John E. Hyde.
The EMBO Journal (1998)
Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins.
Ping Wang;Chung Shinn Lee;Riad Bayoumi;Abdoulaye Djimde.
Molecular and Biochemical Parasitology (1997)
Major surface antigen gene of a human malaria parasite cloned and expressed in bacteria
Roger Hall;John E. Hyde;Mike Goman;David L. Simmons.
John E. Hyde.
Trends in Parasitology (2005)
Drug-resistant malaria - an insight.
John E. Hyde.
FEBS Journal (2007)
Prevalence of Toxoplasma gondii in commercial meat products as monitored by polymerase chain reaction--food for thought?
Tanya V. Aspinall;Damian Marlee;John E. Hyde;Paul F.G. Sims.
International Journal for Parasitology (2002)
Mechanisms of resistance of Plasmodium falciparum to antimalarial drugs.
John E. Hyde.
Microbes and Infection (2002)
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