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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
11564
World Ranking
13846
National Ranking
5856

Overview

John A. Cook is affiliated with the National Institutes of Health in the United States and has contributed to research primarily in the fields of Medicine, and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Molecular Biology, Radiology, Nuclear Medicine and Imaging, Physiology, Immunology, and Biotechnology.

The scientist has focused their research on topics such as Effects of Radiation Exposure, Telomeres, Telomerase, and Senescence, Immune cells in cancer, Cancer Research and Treatments, Heat shock proteins research, Radiation Therapy and Dosimetry, and Lipid metabolism and disorders.

Cook's recent publications include the following:

  • Radiation-Induced Senescence Reprograms Secretory and Metabolic Pathways in Colon Cancer HCT-116 Cells (2021), published in International Journal of Molecular Sciences
  • Pharmacological Inhibition of HSP90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis (2021), published in International Journal of Radiation Oncology*Biology*Physics
  • The antioxidant tempol transforms gut microbiome to resist obesity in female C3H mice fed a high fat diet (2021), published in Free Radical Biology and Medicine
  • The effect of modulation of gut microbiome profile on radiation-induced carcinogenesis and survival (2022), published in Journal of Radiation Research
  • Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation: What We Need to Know and How to Manage for Prolonged Casualty Care (2023), published in Journal of Special Operations Medicine

Frequent co-authors collaborating with Cook include:

  • Rajani Choudhuri
  • James B. Mitchell
  • Anastasia L. Sowers
  • Murali C. Krishna
  • Sangeeta Gohain

Cook's work has appeared in various scientific journals with multiple contributions to:

  • International Journal of Molecular Sciences
  • International Journal of Radiation Oncology*Biology*Physics
  • Free Radical Biology and Medicine
  • Journal of Radiation Research
  • Journal of Special Operations Medicine

Best Publications

  • Cytotoxic studies of paclitaxel (Taxol) in human tumour cell lines.

    J E Liebmann;J A Cook;C Lipschultz;D Teague

  • The Chemistry and Biology of Nitroxide Compounds

    Benjamin P. Soule;Fuminori Hyodo;Ken ichiro Matsumoto;Nicole L. Simone

  • Viability measurements in mammalian cell systems.

    John A. Cook;James B. Mitchell

  • Reaction Kinetics for Nitrosation of Cysteine and Glutathione in Aerobic Nitric Oxide Solutions at Neutral pH. Insights into the Fate and Physiological Effects of Intermediates Generated in the NO/O2 Reaction

    David A. Wink;Raymond W. Nims;John F. Darbyshire;Danae Christodoulou

  • In Vitro Studies of Taxol as a Radiation Sensitizer in Human Tumor Cells

    James Liebmann;John A. Cook;Joyce Fisher;Diane Teague

  • Chemical biology of nitric oxide: regulation and protective and toxic mechanisms.

    David A. Wink;Ingeborg Hanbauer;Ingeborg Hanbauer;Matthew B. Grisham;Matthew B. Grisham;Francoise Laval;Francoise Laval

  • Ionizing radiation-induced oxidative stress alters miRNA expression.

    Nicole L. Simone;Benjamin P. Soule;David Ly;Anthony D. Saleh

  • Nitric oxide potentiates hydrogen peroxide-induced killing of Escherichia coli.

    R Pacelli;D A Wink;J A Cook;M C Krishna

  • Oxidative stress, redox, and the tumor microenvironment.

    John A. Cook;David Gius;David A. Wink;Murali C. Krishna

  • The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: a direct correlation between nitric oxide formation and protection.

    David A. Wink;John A. Cook;Roberto Pacelli;William DeGraff

  • Superoxide Modulates the Oxidation and Nitrosation of Thiols by Nitric Oxide-derived Reactive Intermediates CHEMICAL ASPECTS INVOLVED IN THE BALANCE BETWEEN OXIDATIVE AND NITROSATIVE STRESS

    David A. Wink;John A. Cook;Sungmee Y. Kim;Yoram Vodovotz

  • The Cytotoxicity of Nitroxyl: Possible Implications for the Pathophysiological Role of NO

    David A. Wink;Martin Feelisch;Jon Fukuto;Danae Chistodoulou

  • Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation.

    Mong Hsun Tsai;John A. Cook;Gadisetti V.R. Chandramouli;William DeGraff

  • Nitric oxide (NO) protects against cellular damage by reactive oxygen species

    David A. Wink;John A. Cook;Roberto Pacelli;James Liebmann

  • Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach

    David Gius;Hengmi Cui;C. Matthew Bradbury;John Cook

  • Cellular Glutathione and Thiol Measurements from Surgically Resected Human Lung Tumor and Normal Lung Tissue

    John A. Cook;Harvey I. Pass;Susan N. Iype;Norman Friedman

  • Convenient colorimetric and fluorometric assays for S-nitrosothiols.

    John A. Cook;Sungmee Y. Kim;Diane Teague;Murali C. Krishna

  • In vitro and In vivo Radiation Sensitization of Human Tumor Cells by a Novel Checkpoint Kinase Inhibitor, AZD7762

    James B. Mitchell;Rajani Choudhuri;Kristin Fabre;Anastasia L. Sowers

  • Nitric Oxide and Some Nitric Oxide Donor Compounds Enhance the Cytotoxicity of Cisplatin

    David A. Wink;John A. Cook;Danae Christodoulou;Murali C. Krishna

  • Nitric oxide protects against alkyl peroxide-mediated cytotoxicity: further insights into the role nitric oxide plays in oxidative stress.

    D.A. Wink;J.A. Cook;M.C. Krishna;I. Hanbauer

Frequent Co-Authors

James B. Mitchell
James B. Mitchell National Institutes of Health
William DeGraff
William DeGraff National Institutes of Health
David A. Wink
David A. Wink National Institutes of Health
Yoram Vodovotz
Yoram Vodovotz University of Pittsburgh
Matthew B. Grisham
Matthew B. Grisham Texas Tech University Health Sciences Center
Harvey I. Pass
Harvey I. Pass New York University
Andrew D. Patterson
Andrew D. Patterson Pennsylvania State University
Peter C. Ford
Peter C. Ford University of California, Santa Barbara
David Gius
David Gius Northwestern University
Frank J. Gonzalez
Frank J. Gonzalez National Institutes of Health

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