World's Best Scientists 2026 revealed!
Jayne Y. Hehir-Kwa

Jayne Y. Hehir-Kwa

D-Index & Metrics

Genetics

D-Index
49
Citations
9528
World Ranking
3999
National Ranking
144

Jayne Y. Hehir-Kwa publication distribution in Genetics in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Genetics in 2026. The highlighted bar marks where Jayne Y. Hehir-Kwa sits on this spectrum.

45–54 publications: 6 scientists 55–64 publications: 10 scientists 65–74 publications: 35 scientists 75–84 publications: 84 scientists 85–94 publications: 102 scientists 95–104 publications: 151 scientists 105–114 publications: 175 scientists 115–124 publications: 203 scientists 125–134 publications: 217 scientists 135–144 publications: 205 scientists 145–154 publications: 193 scientists 155–164 publications: 188 scientists 165–174 publications: 170 scientists 175–184 publications: 178 scientists 185–194 publications: 164 scientists 195–204 publications: 173 scientists 205–214 publications: 159 scientists 215–224 publications: 134 scientists 225–234 publications: 143 scientists 235–244 publications: 105 scientists 245–254 publications: 114 scientists 255–264 publications: 92 scientists 265–274 publications: 88 scientists 275–284 publications: 87 scientists 285–294 publications: 80 scientists 295–304 publications: 62 scientists 305–314 publications: 75 scientists 315–324 publications: 67 scientists 325–334 publications: 60 scientists 335–344 publications: 52 scientists 345–354 publications: 40 scientists 355–364 publications: 48 scientists 365–374 publications: 47 scientists 375–384 publications: 46 scientists 385–394 publications: 31 scientists 395–404 publications: 27 scientists 405–414 publications: 40 scientists 415–424 publications: 30 scientists 425–434 publications: 43 scientists 435–444 publications: 29 scientists 445–454 publications: 14 scientists 455–464 publications: 28 scientists 465–474 publications: 21 scientists 475–484 publications: 21 scientists 485–494 publications: 22 scientists 495–504 publications: 17 scientists 505–514 publications: 12 scientists 515–524 publications: 11 scientists 525–534 publications: 8 scientists 535–544 publications: 8 scientists 545–554 publications: 14 scientists 555–564 publications: 4 scientists 565–574 publications: 11 scientists 575–584 publications: 5 scientists 585–594 publications: 11 scientists 595–604 publications: 12 scientists 605–614 publications: 7 scientists 615–624 publications: 6 scientists 625–634 publications: 10 scientists 635–644 publications: 9 scientists 645–654 publications: 10 scientists 655–664 publications: 6 scientists 665–674 publications: 6 scientists 675–684 publications: 6 scientists 685–694 publications: 4 scientists 695–702 publications: 6 scientists 703+ publications: 100 scientists
45 publications 703+

This scientist: 119 publications — 15th percentile

15% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 703 publications or more.

Jayne Y. Hehir-Kwa D-index placement in Genetics in 2026

The chart shows the D-index (discipline H-index) distribution of Genetics scientists ranked by Research.com in 2026. The highlighted bar marks where Jayne Y. Hehir-Kwa sits on this spectrum.

40–41 D-Index: 24 scientists 42–43 D-Index: 52 scientists 44–45 D-Index: 84 scientists 46–47 D-Index: 112 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 141 scientists 52–53 D-Index: 143 scientists 54–55 D-Index: 145 scientists 56–57 D-Index: 179 scientists 58–59 D-Index: 162 scientists 60–61 D-Index: 175 scientists 62–63 D-Index: 191 scientists 64–65 D-Index: 172 scientists 66–67 D-Index: 184 scientists 68–69 D-Index: 164 scientists 70–71 D-Index: 158 scientists 72–73 D-Index: 150 scientists 74–75 D-Index: 136 scientists 76–77 D-Index: 127 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 111 scientists 82–83 D-Index: 110 scientists 84–85 D-Index: 110 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 102 scientists 90–91 D-Index: 66 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 70 scientists 96–97 D-Index: 54 scientists 98–99 D-Index: 60 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 55 scientists 104–105 D-Index: 45 scientists 106–107 D-Index: 42 scientists 108–109 D-Index: 28 scientists 110–111 D-Index: 39 scientists 112–113 D-Index: 25 scientists 114–115 D-Index: 31 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 34 scientists 120–121 D-Index: 29 scientists 122–123 D-Index: 29 scientists 124–125 D-Index: 18 scientists 126–127 D-Index: 27 scientists 128–129 D-Index: 22 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 11 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 12 scientists 138–139 D-Index: 21 scientists 140–141 D-Index: 4 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 14 scientists 146–147 D-Index: 6 scientists 148–149 D-Index: 10 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 9 scientists 154–155 D-Index: 8 scientists 156–157 D-Index: 8 scientists 158–159 D-Index: 9 scientists 160+ D-Index: 96 scientists
40 D-Index 160+

This scientist: 49 D-Index — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 160 D-Index or more.

Overview

Jayne Y. Hehir-Kwa is affiliated with Radboud University in the Netherlands. Their research spans multiple fields within medicine, biochemistry, genetics, and molecular biology, with a particular focus on molecular biology, genetics, cancer research, oncology, and hematology.

The scientist's work extensively covers topics related to cancer genomics and diagnostics, acute lymphoblastic leukemia research, neuroblastoma research and treatments, genomic variations and chromosomal abnormalities, genomics and rare diseases, acute myeloid leukemia research, and sarcoma diagnosis and treatment.

Key recent papers authored or co-authored by Jayne Y. Hehir-Kwa include:

  • Opposite Modulation of RAC1 by Mutations in TRIO Is Associated with Distinct, Domain-Specific Neurodevelopmental Disorders (2020), The American Journal of Human Genetics
  • Structural variant detection in cancer genomes: computational challenges and perspectives for precision oncology (2021), npj Precision Oncology
  • Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia (2022), Blood
  • Mutation-specific pathophysiological mechanisms define different neurodevelopmental disorders associated with SATB1 dysfunction (2021), The American Journal of Human Genetics
  • Mesenchymal tumor organoid models recapitulate rhabdomyosarcoma subtypes (2022), EMBO Molecular Medicine

Frequent co-authors contributing to the scientist's research include:

  • Bastiaan B.J. Tops
  • Patrick Kemmeren
  • Eugène T.P. Verwiel
  • Lennart Kester
  • Marc van Tuil

Their publications are often found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • European Journal of Cancer
  • HemaSphere
  • The American Journal of Human Genetics

The research primarily contributes to areas including cancer genomics and diagnostics, reflecting a broad engagement in genomics, cancer biology, and hematological studies that intersect with clinical oncology. Their work addresses both fundamental molecular mechanisms and translational aspects of rare and common diseases.

Best Publications

  • Genome sequencing identifies major causes of severe intellectual disability

    Christian Gilissen;Jayne Y. Hehir-Kwa;Djie Tjwan Thung;Maartje van de Vorst

  • Refining analyses of copy number variation identifies specific genes associated with developmental delay

    Bradley P. Coe;Kali Witherspoon;Jill A. Rosenfeld;Bregje W M Van Bon;Bregje W M Van Bon

  • Whole-genome sequence variation, population structure and demographic history of the Dutch population

    Laurent C. Francioli;Androniki Menelaou;Sara L. Pulit;Freerk van Dijk

  • High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression.

    R.P. Kuiper;E.F.P.M. Schoenmakers;S.V. van Reijmersdal;J.Y. Hehir-Kwa

  • A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancer

    Robbert D A Weren;Marjolijn J L Ligtenberg;C Marleen Kets;Richarda M de Voer

  • The Genome of the Netherlands: design, and project goals

    Dorret I. Boomsma;Cisca Wijmenga;Eline P. Slagboom;Morris A. Swertz

  • Genomic microarrays in mental retardation: a practical workflow for diagnostic applications.

    David A. Koolen;Rolph Pfundt;Nicole de Leeuw;Jayne Y. Hehir-Kwa

  • Detection of clinically relevant copy-number variants by exome sequencing in a large cohort of genetic disorders

    Rolph Pfundt;Marisol del Rosario;Lisenka E.L.M. Vissers;Michael P. Kwint

  • Characteristics of de novo structural changes in the human genome

    Wigard P. Kloosterman;Laurent C. Francioli;Tobias Marschall;Jayne Y. Hehir-Kwa

  • The Koolen-de Vries syndrome : A phenotypic comparison of patients with a 17q21.31 microdeletion versus a KANSL1 sequence variant

    David A. Koolen;Rolph Pfundt;Katrin Linda;Gea Beunders

  • Identification of clinically significant, submicroscopic chromosome alterations and UPD in fetuses with ultrasound anomalies using genome-wide 250k SNP array analysis

    B H W Faas;I van der Burgt;A J A Kooper;R Pfundt

  • Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly

    B W M van Bon;A Hoischen;J Hehir-Kwa;A P M de Brouwer

  • Recommendations for reporting results of diagnostic genetic testing (biochemical, cytogenetic and molecular genetic).

    Mireille Claustres;Viktor Kožich;Els Dequeker;Brain Fowler

  • Clinical significance of de novo and inherited copy-number variation.

    A.T. van Silfhout;J.Y. Hehir-Kwa;B.W.M. van Bon;J.H.M. Schuurs-Hoeijmakers

  • Genome-wide Copy Number Profiling on High-density Bacterial Artificial Chromosomes, Single-nucleotide Polymorphisms, and Oligonucleotide Microarrays: A Platform Comparison based on Statistical Power Analysis

    Jayne Y. Hehir-Kwa;Michael Egmont-Petersen;Irene M. Janssen;Dominique Smeets

  • De novo copy number variants associated with intellectual disability have a paternal origin and age bias

    Jayne Y Hehir-Kwa;Benjamín Rodríguez-Santiago;Benjamín Rodríguez-Santiago;Lisenka E Vissers;Nicole de Leeuw

  • Diagnostic exome sequencing in 266 Dutch patients with visual impairment

    Lonneke Haer-Wigman;Wendy A. G. van Zelst-Stams;Rolph Pfundt;L. Ingeborgh van den Born

  • Detection of clinically relevant copy number variants with whole-exome sequencing.

    Joep de Ligt;Philip M. Boone;Rolph Pfundt;Lisenka E.L.M. Vissers

  • Diagnostic Interpretation of Array Data Using Public Databases and Internet Sources

    Nicole de Leeuw;Trijnie Dijkhuizen;Jayne Y. Hehir-Kwa;Nigel P. Carter

  • Reduced purifying selection prevails over positive selection in human copy number variant evolution

    Duc-Quang Nguyen;Caleb P Webber;Jayne Hehir-Kwa;Rolph Pfundt

Frequent Co-Authors

Joris A. Veltman
Joris A. Veltman University of Edinburgh
Rolph Pfundt
Rolph Pfundt Radboud University
Han G. Brunner
Han G. Brunner Radboud University
Lisenka E.L.M. Vissers
Lisenka E.L.M. Vissers Radboud University
Alexander Hoischen
Alexander Hoischen Radboud University
Christian Gilissen
Christian Gilissen Radboud University
Simon E. Fisher
Simon E. Fisher Max Planck Society
Abdel Abdellaoui
Abdel Abdellaoui University of Amsterdam
Per Hoffmann
Per Hoffmann University of Bonn
Ad Geurts van Kessel
Ad Geurts van Kessel Radboud University

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