Jan Desmyter

Overview

Best Publications

• Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds

  Rudi Pauwels;Jan Balzarini;Masanori Baba;Robert Snoeck

  2575
  Citations

• Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

  Rudi Pauwels;Koen Andries;Jan Desmyter;Dominique Schols

  1152
  Citations

• Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro.

  M Baba;R Pauwels;J Balzarini;J Arnout

  690
  Citations

• Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro

  Masanori Baba;Rudi Pauwels;Piet Herdewijn;Erik De Clercq

  505
  Citations

• Human Interferon: Mass Production in a Newly Established Cell Line, MG-63

  A. Billiau;V. G. Edy;Hubertine Heremans;J. Van Damme

  377
  Citations

• Phosphonylmethoxyethyl purine derivatives, a new class of anti-human immunodeficiency virus agents.

  R Pauwels;J Balzarini;D Schols;M Baba

  367
  Citations

• Dextran sulfate and other polyanionic anti-HIV compounds specifically interact with the viral gp120 glycoprotein expressed by T-cells persistently infected with HIV-1.

  Dominique Schols;Rudi Pauwels;Jan Desmyter;Erik De Clercq

  315
  Citations

• Sensitive and rapid assay on MT-4 cells for detection of antiviral compounds against the AIDS virus.

  Rudi Pauwels;Erik De Clercq;Jan Desmyter;Jan Balzarini

  269
  Citations

• Ribavirin antagonizes inhibitory effects of pyrimidine 2',3'-dideoxynucleosides but enhances inhibitory effects of purine 2',3'-dideoxynucleosides on replication of human immunodeficiency virus in vitro.

  M Baba;R Pauwels;J Balzarini;P Herdewijn

  229
  Citations

• Differential Distribution of Hepatitis B Surface Antigen and Hepatitis B Core Antigen in the Liver of Hepatitis B Patients

  M.B. Ray;V.J. Desmet;A.F. Bradburne;J. Desmyter

  225
  Citations

• An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives.

  Z. Debyser;R. Pauwels;K. Andries;J. Desmyter

  219
  Citations

• Administration of human fibroblast interferon in chronic hepatitis-B infection.

  J Desmyter;J De Groote;V.J Desmet;A Billiau

  182
  Citations

• The association of gonorrhoea and syphilis with premature birth and low birthweight.

  G. G. G. Donders;J. Desmyter;D. H. De Wet;F. A. Van Assche

  173
  Citations

• Specific interaction of aurintricarboxylic acid with the human immunodeficiency virus/CD4 cell receptor

  D Schols;M Baba;R Pauwels;J Desmyter

  165
  Citations

• Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir).

  José A. Esté;Cecilia Cabrera;Dominique Schols;Peter Cherepanov

  159
  Citations

• Efficacy of heat-inactivated hepatitis B vaccine in haemodialysis patients and staff. Double-blind placebo-controlled trial.

  J. Desmyter;G. De Groote;J. Colaert;M. Reynders

  153
  Citations

• Activity of a sulfated polysaccharide extracted from the red seaweed Aghardhiella tenera against human immunodeficiency virus and other enveloped viruses

  M. Witvrouw;J. A. Este;J. A. Este;M. Q. Mateu;D. Reymen

  150
  Citations

• Increased Susceptibility of Cells Treated with Interferon to the Toxicity of Polyriboinosinic·Polyribocytidylic Acid

  Ii. William E. Stewart;Erik De Clercq;Alfons Billiau;Jan Desmyter

  149
  Citations

• Antiviral Portrait Series: 4. Polysuifates as Inhibitors of HIV and Other Enveloped Viruses

  M. Witvrouw;J. Desmyter;E. De Clercq

  148
  Citations

• Multiple Drug Resistance to Nucleoside Analogues and Nonnucleoside Reverse Transcriptase Inhibitors in an Efficiently Replicating Human Immunodeficiency Virus Type 1 Patient Strain

  Jean-Claude Schmit;Jacqueline Cogniaux;Philippe Hermans;Christophe Van Vaeck

  144
  Citations