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Genetics

D-Index
53
Citations
32157
World Ranking
3678
National Ranking
121

Overview

Jacob Gratten is a researcher affiliated with the University of Queensland in Australia. Their primary fields of study are Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant focus within subfields such as Genetics, Molecular Biology, Cognitive Neuroscience, Neurology, and Psychiatry and Mental Health.

Gratten's research encompasses a variety of topics, including:

  • Autism Spectrum Disorder Research
  • Epigenetics and DNA Methylation
  • Gut microbiota and health
  • Genetic Associations and Epidemiology
  • Parkinson's Disease Mechanisms and Treatments
  • Child Nutrition and Feeding Issues
  • Inflammatory Bowel Disease

The scientist has published work in multiple venues with the highest frequency in Nature Communications, European Neuropsychopharmacology, Cell, bioRxiv (Cold Spring Harbor Laboratory), and Biological Psychiatry.

Recent notable papers include:

  • "Autism-related dietary preferences mediate autism-gut microbiome associations," 2021, Cell
  • "A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts," 2021, Biological Psychiatry
  • "Analysis of DNA methylation associates the cystine-glutamate antiporter SLC7A11 with risk of Parkinson's disease," 2020, Nature Communications
  • "Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases," 2021, Nature Communications
  • "Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders," 2021, Genome Biology

Gratten frequently collaborates with several co-authors who have contributed extensively to their research. These include Peter M. Visscher, Naomi R. Wray, Chloe X. Yap, Anjali K. Henders, and Leanne Wallace.

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

    James J. Lee;Robbee Wedow;Aysu Okbay;Edward Kong

  • Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

    Mike A Nalls;Cornelis Blauwendraat;Costanza L Vallerga;Karl Heilbron

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

    Aysu Okbay;Bart M L Baselmans;Jan-Emmanuel De Neve;Patrick Turley

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

    Richard Karlsson Linnér;Richard Karlsson Linnér;Pietro Biroli;Edward Kong;S. Fleur W. Meddens;S. Fleur W. Meddens

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

    Alexander Gusev;S. Hong Lee;Gosia Trynka;Hilary Finucane

  • Large-scale genomics unveils the genetic architecture of psychiatric disorders

    Jacob Gratten;Naomi R Wray;Matthew C Keller;Peter M Visscher

  • Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms.

    Cornelis Blauwendraat;Karl Heilbron;Costanza L. Vallerga;Sara Bandres-Ciga

  • Life history trade-offs at a single locus maintain sexually selected genetic variation

    Susan E. Johnston;Jacob Gratten;Jacob Gratten;Camillo Berenos;Jill G. Pilkington

  • Autism-related dietary preferences mediate autism-gut microbiome associations

    Chloe X. Yap;Chloe X. Yap;Anjali K. Henders;Anjali K. Henders;Gail A. Alvares;David L.A. Wood

  • Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

    Qian Zhang;Costanza L. Vallerga;Rosie M. Walker;Tian Lin

  • Complement genes contribute sex-biased vulnerability in diverse disorders

    Nolan Kamitaki;Nolan Kamitaki;Aswin Sekar;Aswin Sekar;Robert E. Handsaker;Robert E. Handsaker;Heather de Rivera;Heather de Rivera

  • Gene mapping in the wild with SNPs: guidelines and future directions.

    Jon Slate;Jake Gratten;Dario Beraldi;Jessica Stapley

  • Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

    Laura M. Huckins;Amanda Dobbyn;Douglas M. Ruderfer;Gabriel Hoffman

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Aysu Okbay;Jonathan P. Beauchamp;Mark Alan Fontana;James J. Lee

  • Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

    Aysu Okbay;Bart M. L. Baselmans;Jan-Emmanuel De Neve;Patrick Turley

Frequent Co-Authors

Peter M. Visscher
Peter M. Visscher University of Oxford
Naomi R. Wray
Naomi R. Wray University of Queensland
Tune H. Pers
Tune H. Pers University of Copenhagen
Tonu Esko
Tonu Esko University of Tartu
Danielle Posthuma
Danielle Posthuma Vrije Universiteit Amsterdam
Jian Yang
Jian Yang University of Birmingham
Patrik K. E. Magnusson
Patrik K. E. Magnusson Karolinska Institute
Bryan J. Mowry
Bryan J. Mowry University of Queensland
Pablo V. Gejman
Pablo V. Gejman NorthShore University HealthSystem
Aarno Palotie
Aarno Palotie University of Helsinki

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Related Online Degrees & Career Pathways

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