World's Best Scientists 2026 revealed!

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Genetics

D-Index
53
Citations
16604
World Ranking
3698
National Ranking
130

Overview

Hamdi Mbarek is affiliated with Vrije Universiteit Amsterdam in the Netherlands and has a research focus rooted primarily in biochemistry, genetics, and molecular biology, with a secondary emphasis on medicine. Their scholarly output spans various subfields including genetics, molecular biology, pediatrics, perinatology and child health, infectious diseases, and immunology.

The scientist's work covers a range of topics, reflecting interdisciplinary approaches within genetics and genomics. The main topics they have contributed to include:

  • Genetic Associations and Epidemiology
  • Genomics and Rare Diseases
  • Assisted Reproductive Technology and Twin Pregnancy
  • Genomic Variations and Chromosomal Abnormalities
  • SARS-CoV-2 and COVID-19 Research
  • Epigenetics and DNA Methylation
  • Ovarian Function and Disorders

Mbarek's recent scientific papers demonstrate engagement with large-scale genetic studies and their applications to human health and disease. Notable publications include:

  • "Mapping the human genetic architecture of COVID-19," 2021, published in Nature
  • "Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank," 2020, published in Molecular Psychiatry
  • "Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk," 2023, published in Nature Genetics
  • "A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank," 2020, published in Nature Communications
  • "Qatar genome: Insights on genomics from the Middle East," 2022, published in Human Mutation

Frequent collaborators with whom Mbarek has coauthored multiple papers include:

  • Chadi Saad (29 coauthored works)
  • Said I. Ismail (23 coauthored works)
  • Yasser Al-Sarraj (21 coauthored works)
  • Wadha Al-Muftah (19 coauthored works)
  • Radja Badji (19 coauthored works)

Their research has appeared in several publication venues repeatedly, indicating areas of active contribution and professional engagement. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory) - 8 publications
  • Nature Communications - 4 publications
  • Human Reproduction - 4 publications
  • The American Journal of Human Genetics - 4 publications
  • Nature Genetics - 3 publications

Best Publications

  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    Naomi R. Wray;Stephan Ripke;Stephan Ripke;Stephan Ripke;Manuel Mattheisen;MacIej Trzaskowski

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

    Raymond K. Walters;Raymond K. Walters;Renato Polimanti;Emma C. Johnson;Jeanette N. McClintick

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Felix R. Day;Deborah J. Thompson;Hannes Helgason;Hannes Helgason;Daniel I. Chasman

  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Nicole M Warrington;Robin N Beaumont;Momoko Horikoshi;Felix R Day

  • Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    Florence Demenais;Florence Demenais;Patricia Margaritte-Jeannin;Patricia Margaritte-Jeannin;Kathleen C. Barnes;William O.C. Cookson

  • Genome-wide analysis identifies 12 loci influencing human reproductive behavior

    Nicola Barban;Rick Jansen;Ronald De Vlaming;Ahmad Vaez;Ahmad Vaez

  • Genetic insights into biological mechanisms governing human ovarian ageing.

    Katherine S. Ruth;Felix R. Day;Jazib Hussain;Ana Martínez-Marchal

  • KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

    Gunter Schumann;Chunyu Liu;Chunyu Liu;Paul F. O'Reilly;He Gao

  • The adult Netherlands twin register: Twenty-five years of survey and biological data collection

    Gonneke Willemsen;Jacqueline M. Vink;Abdel Abdellaoui;Anouk den Braber

  • A Genome-Wide Association Study of Chronic Hepatitis B Identified Novel Risk Locus in a Japanese Population

    Hamdi Mbarek;Hidenori Ochi;Yuji Urabe;Vinod Kumar

  • Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

    Leanne K. Küpers;Claire Monnereau;Gemma C. Sharp;Paul Yousefi;Paul Yousefi

  • Polygenic dissection of major depression clinical heterogeneity

    Yuri Milaneschi;F. Lamers;Wouter Peyrot;Abdel Abdellaoui

  • Meta-analysis of Genome-Wide Association Studies for Extraversion: Findings from the Genetics of Personality Consortium

    Stephanie M. van den Berg;Marleen H. M. de Moor;Karin J. H. Verweij;Karin J. H. Verweij;Robert F. Krueger

  • Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium

    S Stringer;C.C. Minică;Karin J. H. Verweij;H Mbarek

  • Sex differences in the human peripheral blood transcriptome

    Rick Jansen;Sandra Batista;Andrew I. Brooks;Jay A. Tischfield

  • Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

    Lee Ph;Anttila;Won H

  • KLB is associated with alcohol drinking, and its gene product beta-Klotho is necessary for FGF21 regulation of alcohol preference

    Gunter Schumann;Chunyu Liu;Paul O'Reilly;He Gao

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Day Fr;Thompson Dj;elgason H;Chasman Di

  • Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    Florence Demenais;Patricia Margaritte-Jeannin;Kathleen C. Barnes;William O. C. Cookson

Frequent Co-Authors

Dorret I. Boomsma
Dorret I. Boomsma Vrije Universiteit Amsterdam
Jouke-Jan Hottenga
Jouke-Jan Hottenga Hamad bin Khalifa University
Gonneke Willemsen
Gonneke Willemsen Vrije Universiteit Amsterdam
Nicholas G. Martin
Nicholas G. Martin QIMR Berghofer Medical Research Institute
Grant W. Montgomery
Grant W. Montgomery University of Queensland
Eco J. C. de Geus
Eco J. C. de Geus Vrije Universiteit Amsterdam
Tonu Esko
Tonu Esko University of Tartu
Jaakko Kaprio
Jaakko Kaprio University of Helsinki
Caroline Hayward
Caroline Hayward University of Edinburgh

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