World's Best Scientists 2026 revealed!
Dimitrios Tsikas

Dimitrios Tsikas

D-Index & Metrics

Chemistry

D-Index
68
Citations
19672
World Ranking
6433
National Ranking
467

Overview

Dimitrios Tsikas is a researcher affiliated with Hannover Medical School in Germany. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Physiology, Spectroscopy, Biochemistry, and Cardiology and Cardiovascular Medicine.

Their work addresses a wide range of topics in biomedical research, including:

  • Nitric Oxide and Endothelin Effects
  • Mass Spectrometry Techniques and Applications
  • Metabolomics and Mass Spectrometry Studies
  • Analytical Chemistry and Chromatography
  • Muscle Metabolism and Nutrition
  • Amino Acid Enzymes and Metabolism
  • Sulfur Compounds in Biology

Dimitrios Tsikas has published extensively in several scientific journals. Frequent publication venues include:

  • Amino Acids (17 publications)
  • Molecules (13 publications)
  • Journal of Clinical Medicine (11 publications)
  • Journal of Chromatography B (8 publications)
  • International Journal of Molecular Sciences (6 publications)

They have collaborated frequently with a number of researchers, among whom are:

  • Alexander Bollenbach (20 joint publications)
  • Svetlana Baskal (16 joint publications)
  • Bibiana Beckmann (12 joint publications)
  • Thomas Lücke (9 joint publications)
  • Stefan Ückert (8 joint publications)

Selected recent papers authored by Dimitrios Tsikas demonstrate the scope of their work:

  • "Urinary Dimethylamine (DMA) and Its Precursor Asymmetric Dimethylarginine (ADMA) in Clinical Medicine, in the Context of Nitric Oxide (NO) and Beyond," 2020, Journal of Clinical Medicine
  • "Acetazolamide and human carbonic anhydrases: retrospect, review and discussion of an intimate relationship," 2023, Journal of Enzyme Inhibition and Medicinal Chemistry
  • "N-Acetyl-L-cysteine in human rheumatoid arthritis and its effects on nitric oxide (NO) and malondialdehyde (MDA): analytical and clinical considerations," 2022, Amino Acids

While many of their papers focus directly on biochemical pathways and clinical implications, they also contribute to broader topics in clinical medicine and pharmacology.

Best Publications

  • Assessment of lipid peroxidation by measuring malondialdehyde (MDA) and relatives in biological samples: Analytical and biological challenges

    Dimitrios Tsikas

  • Analysis of nitrite and nitrate in biological fluids by assays based on the Griess reaction: appraisal of the Griess reaction in the L-arginine/nitric oxide area of research.

    Dimitrios Tsikas

  • LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of S-adenosylmethionine-dependent methyltransferases.

    Rainer H. Böger;Karsten Sydow;Jürgen Borlak;Thomas Thum

  • Cardiovascular Effects of Systemic Nitric Oxide Synthase Inhibition With Asymmetrical Dimethylarginine in Humans

    Jan T. Kielstein;Burcu Impraim;Solveig Simmel;Stefanie M. Bode-Böger

  • Endothelial Nitric Oxide Synthase Uncoupling Impairs Endothelial Progenitor Cell Mobilization and Function in Diabetes

    Thomas Thum;Daniela Fraccarollo;Maximilian Schultheiss;Sabrina Froese

  • Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers

    Daniela Giustarini;Isabella Dalle-Donne;Dimitrios Tsikas;Ranieri Rossi

  • Methods of quantitative analysis of the nitric oxide metabolites nitrite and nitrate in human biological fluids.

    Dimitrios Tsikas

  • Age-Dependent Impairment of Endothelial Progenitor Cells Is Corrected by Growth Hormone Mediated Increase of Insulin-Like Growth Factor-1

    Thomas Thum;Sarah Hoeber;Sabrina Froese;Ivonne Klink

  • Urinary 8-iso-prostaglandin F2alpha as a risk marker in patients with coronary heart disease: a matched case-control study.

    Edzard Schwedhelm;Asja Bartling;Henrike Lenzen;Dimitrios Tsikas

  • L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship.

    Stefanie M. Bode‐Böger;Rainer H. Böger;Andrea Galland;Dimitrios Tsikas

  • Endogenous nitric oxide synthase inhibitors are responsible for the L‐arginine paradox

    Dimitrios Tsikas;Rainer H Böger;Jörg Sandmann;Stefanie M Bode-Böger

  • Simultaneous derivatization and quantification of the nitric oxide metabolites nitrite and nitrate in biological fluids by gas chromatography/mass spectrometry.

    Dimitrios Tsikas

  • Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine.

    Thomas Thum;Dimitrios Tsikas;Sylvia Stein;Maximilian Schultheiss

  • l-Arginine Induces Nitric Oxide–Dependent Vasodilation in Patients With Critical Limb Ischemia A Randomized, Controlled Study

    Stefanie M. Bode-Böger;Rainer H. Böger;Heiko Alfke;Doris Heinzel

  • L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects.

    S. M. Bode-Böger;R. H. Böger;A. Creutzig;D. Tsikas

  • Measurement of Nitrite and Nitrate in Biological Fluids by Gas Chromatography–Mass Spectrometry and by the Griess Assay: Problems with the Griess Assay—Solutions by Gas Chromatography–Mass Spectrometry

    Dimitrios Tsikas;Frank-Mathias Gutzki;Stefan Rossa;Heinke Bauer

  • Quantification of endocannabinoids in biological systems by chromatography and mass spectrometry: A comprehensive review from an analytical and biological perspective☆

    Alexander A. Zoerner;Frank-Mathias Gutzki;Sandor Batkai;Marcus May

  • Quantitative determination of circulating and urinary asymmetric dimethylarginine (ADMA) in humans by gas chromatography-tandem mass spectrometry as methyl ester tri(N-pentafluoropropionyl) derivative.

    Dimitrios Tsikas;Bibiana Schubert;Frank-Mathias Gutzki;Jörg Sandmann

  • A critical review and discussion of analytical methods in the L-arginine/nitric oxide area of basic and clinical research.

    Dimitrios Tsikas

  • Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes

    Arash Haghikia;Ewa Missol-Kolka;Dimitrios Tsikas;Letizia Venturini

  • Improvement in Left Ventricular Remodeling by the Endothelial Nitric Oxide Synthase Enhancer AVE9488 After Experimental Myocardial Infarction

    Daniela Fraccarollo;Julian D. Widder;Paolo Galuppo;Thomas Thum

  • Chronic Angiotensin II Receptor Blockade Reduces (Intra)Renal Vascular Resistance in Patients with Type 2 Diabetes

    Danilo Fliser;Kathrin-Kristin Wagner;Astrid Loos;Dimitrios Tsikas

Frequent Co-Authors

Jens Jordan
Jens Jordan German Aerospace Center
Sandor Batkai
Sandor Batkai Cardior Pharmaceuticals
Thomas Thum
Thomas Thum Hannover Medical School
Stephan J. L. Bakker
Stephan J. L. Bakker University Medical Center Groningen
Johann Bauersachs
Johann Bauersachs Hannover Medical School
Ranieri Rossi
Ranieri Rossi University of Siena
Daniela Giustarini
Daniela Giustarini University of Siena
Harry van Goor
Harry van Goor Radboud University
Rainer H. Böger
Rainer H. Böger Universität Hamburg
Jens M. Hohlfeld
Jens M. Hohlfeld Fraunhofer Institute for Toxicology and Experimental Medicine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Chemistry in the USA opens doors to a variety of exciting career pathways. Many graduates pursue roles in healthcare and pharmaceuticals, with options ranging from becoming a pharmacist to entering pharmaceutical sales. For those interested in patient care and medication management, learning how to become a pharmacist salary details can be a valuable resource for understanding this profession’s financial rewards.

Alternatively, a career in pharmaceutical sales offers a dynamic environment that combines science knowledge with business skills. Exploring pharma sales rep salary insights can help aspiring candidates evaluate this route.

For those drawn toward forensic science or medical examination, studying chemistry is often a foundational step. Programs like an affordable forensic science bachelor degree online are widely accessible and prepare students for specialized roles.

Roles such as medical examiner assistants also rely heavily on chemistry knowledge. Learning more about how to become a medical examiner assistant gives insight into education requirements and career outlooks within this important field.

Best Scientists Citing Dimitrios Tsikas

Trending Scientists