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David L. Popham

David L. Popham

D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
7937
World Ranking
18434
National Ranking
7527

Overview

David L. Popham is a researcher affiliated with Virginia Tech in the United States, with a focus on fields related to biochemistry, genetics, and molecular biology. Their work spans over 22 publications in these areas, with significant contributions also made in medicine. The scientist's subfield expertise includes infectious diseases, genetics, molecular biology, ecology, and materials chemistry.

Popham's research interests cover several main topics including bacterial genetics and biotechnology, Clostridium difficile and Clostridium perfringens research, bacteriophages and microbial interactions, viral gastroenteritis research and epidemiology, enzyme structure and function, amino acid enzymes and metabolism, as well as nosocomial infections in intensive care units.

The scientist has published extensively in various peer-reviewed venues. The most frequent publication outlets include:

  • Journal of Bacteriology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Developmental Cell
  • Applied and Environmental Microbiology

Recent publications by David L. Popham demonstrate continued activity in microbiology and bacterial cell biology. Selected recent papers include:

  • "Lysozyme Resistance in Clostridioides difficile Is Dependent on Two Peptidoglycan Deacetylases," 2020, Journal of Bacteriology
  • "Bacterial developmental checkpoint that directly monitors cell surface morphogenesis," 2022, Developmental Cell
  • "A Family of Spore Lipoproteins Stabilizes the Germination Apparatus by Altering Inner Spore Membrane Fluidity in Bacillus subtilis Spores," 2023, Journal of Bacteriology
  • "Identification of a family of peptidoglycan transpeptidases reveals that Clostridioides difficile requires noncanonical cross-links for viability," 2024, Proceedings of the National Academy of Sciences
  • "Comparative Study of Bacterial SPOR Domains Identifies Functionally Important Differences in Glycan Binding Affinity," 2022, Journal of Bacteriology

Throughout their research career, Popham has collaborated regularly with several co-authors, including Gabriela M. Kaus, Ute Müh, Matthew J. Flores, Craig D. Ellermeier, and David S. Weiss. Each of these collaborators has appeared in at least four publications alongside Popham, indicating ongoing research partnerships.

Best Publications

  • Expression of sigma 54 (ntrA)-dependent genes is probably united by a common mechanism.

    S Kustu;E Santero;J Keener;D Popham

  • A eukaryotic-like Ser/Thr kinase signals bacteria to exit dormancy in response to peptidoglycan fragments

    Ishita M. Shah;Maria-Halima Laaberki;David L. Popham;Jonathan Dworkin

  • Function of a Bacterial Activator Protein that Binds to Transcriptional Enhancers

    David L. Popham;Daniel Szeto;John Keener;Sydney Kustu

  • Muramic lactam in peptidoglycan of Bacillus subtilis spores is required for spore outgrowth but not for spore dehydration or heat resistance.

    David L. Popham;Jari Helin;Catherine E. Costello;Peter Setlow

  • A bacterial enhancer functions to tether a transcriptional activator near a promoter

    Andrew Wedel;David S. Weiss;David Popham;Peter Dröge

  • Role of penicillin-binding proteins in bacterial cell morphogenesis

    David L Popham;Kevin D Young

  • Analysis of the properties of spores of Bacillus subtilis prepared at different temperatures.

    E. Melly;P.C. Genest;M.E. Gilmore;S. Little

  • Specialized peptidoglycan of the bacterial endospore: the inner wall of the lockbox

    D. L. Popham

  • Analysis of the peptidoglycan structure of Bacillus subtilis endospores.

    David L. Popham;Jari Helin;Catherine E. Costello;Peter Setlow

  • Peptidoglycan Synthesis in the Absence of Class A Penicillin-Binding Proteins in Bacillus subtilis

    Derrell C. McPherson;David L. Popham

  • Heat, hydrogen peroxide, and UV resistance of Bacillus subtilis spores with increased core water content and with or without major DNA-binding proteins.

    D L Popham;S Sengupta;P Setlow

  • Reduction in membrane phosphatidylglycerol content leads to daptomycin resistance in Bacillus subtilis

    Anna-Barbara Hachmann;Elif Sevim;Ahmed Gaballa;David L. Popham

  • Structural analysis of Bacillus subtilis spore peptidoglycan during sporulation.

    Jennifer Meador-Parton;David L. Popham

  • Daughter Cell Separation by Penicillin-Binding Proteins and Peptidoglycan Amidases in Escherichia coli

    Richa Priyadarshini;David L. Popham;Kevin D. Young

  • Structure and Synthesis of Cell Wall, Spore Cortex, Teichoic Acids, S-Layers, and Capsules

    Simon J. Foster;David L. Popham

  • The bacterial septal ring protein RlpA is a lytic transglycosylase that contributes to rod shape and daughter cell separation in Pseudomonas aeruginosa

    Matthew A. Jorgenson;Yan Chen;Atsushi Yahashiri;David L. Popham

  • Roles of Low-Molecular-Weight Penicillin-Binding Proteins in Bacillus subtilis Spore Peptidoglycan Synthesis and Spore Properties

    David L. Popham;Meghan E. Gilmore;Peter Setlow

  • Phenotypes of Bacillus subtilis mutants lacking multiple class A high-molecular-weight penicillin-binding proteins.

    D L Popham;P Setlow

  • Sulfur and nitrogen limitation in Escherichia coli K-12: specific homeostatic responses.

    Prasad Gyaneshwar;Oleg Paliy;Jon McAuliffe;David L. Popham

  • Discovery and characterization of three new Escherichia coli septal ring proteins that contain a SPOR domain: DamX, DedD, and RlpA

    S. J. Ryan Arends;Kyle B Williams;Renada J. Scott;Silvana Rolong

Frequent Co-Authors

Peter Setlow
Peter Setlow University of Connecticut Health Center
Sydney Kustu
Sydney Kustu University of California, Berkeley
Adam Driks
Adam Driks Loyola University Chicago
Richard F. Helm
Richard F. Helm Virginia Tech
Catherine E. Costello
Catherine E. Costello Boston University
Kevin D. Young
Kevin D. Young University of Arkansas for Medical Sciences
Tiina Reponen
Tiina Reponen University of Cincinnati
Atin Adhikari
Atin Adhikari Georgia Southern University
Sergey A. Grinshpun
Sergey A. Grinshpun University of Cincinnati
Richard Losick
Richard Losick Harvard University

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