D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 40 Citations 9,237 62 World Ranking 16989 National Ranking 6992

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Immune system

His scientific interests lie mostly in Immunology, Virology, Virus, Viral load and Viral replication. His Virology research integrates issues from HIV vaccine and Mononuclear phagocyte system. His Virus study introduces a deeper knowledge of Genetics.

His Viral load research is multidisciplinary, relying on both Hiv infected, Viremia, T cell and Simian immunodeficiency virus. His Viremia study combines topics from a wide range of disciplines, such as Gut-associated lymphoid tissue, Lymphatic system, T lymphocyte and Immunity. The study incorporates disciplines such as CD14, Bone marrow, In vivo and Immunodeficiency in addition to Viral replication.

His most cited work include:

  • CD8+ T-cell responses to different HIV proteins have discordant associations with viral load (914 citations)
  • Persistence of HIV in Gut-Associated Lymphoid Tissue despite Long-Term Antiretroviral Therapy (422 citations)
  • Improved Coreceptor Usage Prediction and Genotypic Monitoring of R5-to-X4 Transition by Motif Analysis of Human Immunodeficiency Virus Type 1 env V3 Loop Sequences (418 citations)

What are the main themes of his work throughout his whole career to date?

David C. Nickle mainly focuses on Virology, Genetics, Virus, Immunology and Viral disease. The Virology study combines topics in areas such as Epitope, Antigen and CTL*. In general Genetics study, his work on Genetic variation, Phylogenetic tree, Gene and Recombination often relates to the realm of Substitution, thereby connecting several areas of interest.

David C. Nickle combines subjects such as SNP and Regulation of gene expression with his study of Immunology. His work on Lentivirus as part of general Viral disease study is frequently linked to Compartmentalization, therefore connecting diverse disciplines of science. His biological study spans a wide range of topics, including Viremia, Human leukocyte antigen and T cell.

He most often published in these fields:

  • Virology (46.55%)
  • Genetics (37.93%)
  • Virus (29.31%)

What were the highlights of his more recent work (between 2009-2021)?

  • Genome-wide association study (6.90%)
  • Single-nucleotide polymorphism (5.17%)
  • Gene expression (3.45%)

In recent papers he was focusing on the following fields of study:

David C. Nickle mostly deals with Genome-wide association study, Single-nucleotide polymorphism, Gene expression, Macrophage migration inhibitory factor and Pathogenesis. His Genome-wide association study study results in a more complete grasp of Genetics. His study in Single-nucleotide polymorphism is interdisciplinary in nature, drawing from both Asthma, Bioinformatics and Gene isoform.

The Gene expression study combines topics in areas such as SNP and Molecular biology. His SNP study frequently involves adjacent topics like Immunology. His research in Pathogenesis intersects with topics in Phenotype, Lesion and Knockout mouse.

Between 2009 and 2021, his most popular works were:

  • Identification and validation of genes affecting aortic lesions in mice (42 citations)
  • Increased Breadth and Depth of Cytotoxic T Lymphocytes Responses against HIV-1-B Nef by Inclusion of Epitope Variant Sequences (20 citations)
  • Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19. (4 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Immune system

David C. Nickle focuses on Genome-wide association study, Lesion, Pathogenesis, Coronary artery disease and Phenotype. His work deals with themes such as Mendelian Randomization Analysis, Quantitative trait locus, Expression quantitative trait loci, ABO blood group system and Human genetics, which intersect with Genome-wide association study. The various areas that David C. Nickle examines in his Lesion study include Knockout mouse and Genetic association.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

Photini Kiepiela;Kholiswa Ngumbela;Christina Thobakgale;Dhanwanthie Ramduth.
Nature Medicine (2007)

1092 Citations

Persistence of HIV in Gut-Associated Lymphoid Tissue despite Long-Term Antiretroviral Therapy

Tae Wook Chun;David C. Nickle;Jesse S. Justement;Jennifer H. Meyers.
The Journal of Infectious Diseases (2008)

585 Citations

Improved Coreceptor Usage Prediction and Genotypic Monitoring of R5-to-X4 Transition by Motif Analysis of Human Immunodeficiency Virus Type 1 env V3 Loop Sequences

Mark A. Jensen;Fu Sheng Li;Angélique B. Van 't Wout;David C. Nickle.
Journal of Virology (2003)

527 Citations

Aspergillus lentulus sp. nov., a New Sibling Species of A. fumigatus

S. Arunmozhi Balajee;Jennifer L. Gribskov;Edward Hanley;David Nickle.
Eukaryotic Cell (2005)

453 Citations

Evidence for human immunodeficiency virus type 1 replication in vivo in CD14(+) monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy.

Tuofu Zhu;David Muthui;Sarah Holte;David Nickle.
Journal of Virology (2002)

434 Citations

HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir

Tae Wook Chun;David C. Nickle;J. Shawn Justement;Danielle Large.
Journal of Clinical Investigation (2005)

356 Citations

Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial

Gregory J. Dore;Frederick Altice;Alain H. Litwin;Olav Dalgard.
Annals of Internal Medicine (2016)

316 Citations

Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

Ke Hao;Yohan Bossé;David C. Nickle;Peter D. Paré.
PLOS Genetics (2012)

308 Citations

Cloning and Characterization of PDK4 on 7q21.3 Encoding a Fourth Pyruvate Dehydrogenase Kinase Isoenzyme in Human

Joie Rowles;Stephen W. Scherer;Tina Xi;Martin Majer.
Journal of Biological Chemistry (1996)

302 Citations

Founder effects in the assessment of HIV polymorphisms and HLA allele associations.

Tanmoy Bhattacharya;Tanmoy Bhattacharya;Marcus Daniels;David Heckerman;Brian Foley.
Science (2007)

301 Citations

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