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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
17526
World Ranking
10071
National Ranking
4405

Overview

David C. Nickle is affiliated with Monoceros Biosystems in the United States and contributes extensively to the field of medicine, particularly focusing on pulmonary and respiratory medicine. Their research spans multiple interconnected subfields including infectious diseases, physiology, immunology, and oncology.

The main topics covered in their work include:

  • Asthma and respiratory diseases
  • COVID-19 clinical research studies
  • SARS-CoV-2 and COVID-19 research
  • IL-33, ST2, and ILC pathways
  • Chronic obstructive pulmonary disease (COPD) research
  • Neonatal respiratory health research
  • Respiratory viral infections research

They have frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), the University of Groningen research database (University of Groningen / Centre for Information Technology), CHEST Journal, American Journal of Physiology-Lung Cellular and Molecular Physiology, and Scientific Reports.

Notable recent papers include:

  • Neutrophilic inflammation in the respiratory mucosa predisposes to RSV infection, 2020, Science
  • Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank, 2021, Communications Biology
  • Rhinovirus and asthma: Challenges and opportunities, 2020, Reviews in Medical Virology
  • Detection of respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes, 2021, Nature Microbiology
  • Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19, 2021, Human Genetics

David C. Nickle collaborates frequently with several researchers, including Don D. Sin, Yohan Bossé, Philippe Joubert, Maarten van den Berge, and Wim Timens.

Best Publications

  • CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

    Photini Kiepiela;Kholiswa Ngumbela;Christina Thobakgale;Dhanwanthie Ramduth

  • Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

    James D McKay;Rayjean J Hung;Younghun Han;Xuchen Zong

  • Persistence of HIV in Gut-Associated Lymphoid Tissue despite Long-Term Antiretroviral Therapy

    Tae Wook Chun;David C. Nickle;Jesse S. Justement;Jennifer H. Meyers

  • New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

    Shrine N;Guyatt Al;Erzurumluoglu Am;Jackson Ve;Jackson Ve;Jackson Ve

  • Improved Coreceptor Usage Prediction and Genotypic Monitoring of R5-to-X4 Transition by Motif Analysis of Human Immunodeficiency Virus Type 1 env V3 Loop Sequences

    Mark A. Jensen;Fu Sheng Li;Angélique B. Van 't Wout;David C. Nickle

  • Aspergillus lentulus sp. nov., a New Sibling Species of A. fumigatus

    S. Arunmozhi Balajee;Jennifer L. Gribskov;Edward Hanley;David Nickle

  • Evidence for human immunodeficiency virus type 1 replication in vivo in CD14(+) monocytes and its potential role as a source of virus in patients on highly active antiretroviral therapy.

    Tuofu Zhu;David Muthui;Sarah Holte;David Nickle

  • Elbasvir-Grazoprevir to Treat Hepatitis C Virus Infection in Persons Receiving Opioid Agonist Therapy: A Randomized Trial

    Gregory J. Dore;Frederick Altice;Alain H. Litwin;Olav Dalgard

  • Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

    Ke Hao;Yohan Bossé;David C. Nickle;Peter D. Paré

  • HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir

    Tae Wook Chun;David C. Nickle;J. Shawn Justement;Danielle Large

  • Founder effects in the assessment of HIV polymorphisms and HLA allele associations.

    Tanmoy Bhattacharya;Tanmoy Bhattacharya;Marcus Daniels;David Heckerman;Brian Foley

  • Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

    Louise V. Wain;Louise V. Wain;Nick Shrine;María Soler Artigas;A. Mesut Erzurumluoglu

  • ViroBLAST: a stand-alone BLAST web server for flexible queries of multiple databases and user's datasets.

    Wenjie Deng;David C. Nickle;Gerald H. Learn;Brandon Maust

  • Cloning and Characterization of PDK4 on 7q21.3 Encoding a Fourth Pyruvate Dehydrogenase Kinase Isoenzyme in Human

    Joie Rowles;Stephen W. Scherer;Tina Xi;Martin Majer

  • Dual HIV-1 infection associated with rapid disease progression.

    Geoffrey S. Gottlieb;David C. Nickle;Mark A. Jensen;Kim G. Wong

  • Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study

    Richard J Allen;Joanne Porte;Rebecca Braybrooke;Carlos Flores

  • Molecular studies reveal frequent misidentification of Aspergillus fumigatus by morphotyping.

    S. Arunmozhi Balajee;David Nickle;Janos Varga;Kieren A. Marr;Kieren A. Marr

  • Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence.

    Hisayoshi Mochizuki;Stephen W Scherer;Tina Xi;David C Nickle

  • Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.

    Richard J. Allen;Beatriz Guillen-Guio;Justin M. Oldham;Shwu-Fan Ma

  • Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

    Louise V. Wain;Nick Shrine;Maria Soler Artigas;A. Mesut Erzurumluoglu

Frequent Co-Authors

James I. Mullins
James I. Mullins University of Washington
Yohan Bossé
Yohan Bossé Université Laval
Gerald H. Learn
Gerald H. Learn University of Pennsylvania
Ke Hao
Ke Hao Icahn School of Medicine at Mount Sinai
Wim Timens
Wim Timens University Medical Center Groningen
Louise V. Wain
Louise V. Wain University of Leicester
Bruce D. Walker
Bruce D. Walker Harvard University
Martin D. Tobin
Martin D. Tobin University of Leicester
Christian Brander
Christian Brander University of Vic - Central University of Catalonia
David Heckerman
David Heckerman Microsoft (United States)

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