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Biology and Biochemistry

D-Index
53
Citations
8810
World Ranking
16298
National Ranking
6749

Overview

David A. Ostrov is affiliated with the University of Florida in the United States. Their research focuses primarily on Medicine, with significant contributions in Biochemistry, Genetics, and Molecular Biology. The subfields of their work include Infectious Diseases, Molecular Biology, Immunology, Oncology, and Pharmacology.

The scientist's recent publications cover a range of topics related to viral infections, immunology, and drug reactions. Notable papers include:

  • Independent infections of porcine deltacoronavirus among Haitian children, 2021, published in Nature
  • Identification of antiviral antihistamines for COVID-19 repurposing, 2020, published in Biochemical and Biophysical Research Communications
  • Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis, 2021, published in The Journal of Immunology
  • Emergence of porcine delta-coronavirus pathogenic infections among children in Haiti through independent zoonoses and convergent evolution, 2021, published in bioRxiv (Cold Spring Harbor Laboratory)
  • Human Leukocyte Antigen B*14:01 and B*35:01 Are Associated With Trimethoprim-Sulfamethoxazole Induced Liver Injury, 2020, published in Hepatology

Frequent co-authors with whom David A. Ostrov has collaborated extensively include:

  • Danmeng Li
  • Marco Salemi
  • Cuong Q. Nguyen
  • Massimiliano S. Tagliamonte
  • Carla Mavian

Their work is regularly published in several scientific venues, with multiple publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Immunology
  • Biochemical and Biophysical Research Communications
  • PLoS ONE
  • International Journal of Molecular Sciences

The main topics of David A. Ostrov's research are related to:

  • SARS-CoV-2 and COVID-19 Research
  • Viral gastroenteritis research and epidemiology
  • Drug-Induced Adverse Reactions
  • Animal Virus Infections Studies
  • COVID-19 Clinical Research Studies
  • Salivary Gland Disorders and Functions
  • Urticaria and Related Conditions

Best Publications

  • Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

    David A. Ostrov;Barry J. Grant;Yuri A. Pompeu;John Sidney

  • Independent infections of porcine deltacoronavirus among Haitian children.

    John A. Lednicky;Massimiliano S. Tagliamonte;Sarah K. White;Maha A. Elbadry

  • Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.

    Anderson J. Ferreira;Vinayak Shenoy;Yoriko Yamazato;Srinivas Sriramula

  • Structure-Based Identification of Small-Molecule Angiotensin-Converting Enzyme 2 Activators as Novel Antihypertensive Agents

    José A. Hernández Prada;Anderson J. Ferreira;Michael J. Katovich;Vinayak Shenoy

  • A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth.

    Vita M. Golubovskaya;Carl Nyberg;Min Zheng;Frederick Kweh

  • A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors

    Debra Akin;S. Keisin Wang;Pouran Habibzadegah-Tari;Brian Law

  • Discovery of Novel DNA Gyrase Inhibitors by High-Throughput Virtual Screening

    David A. Ostrov;José A. Hernández Prada;Patrick E. Corsino;Kathryn A. Finton

  • Structure of murine CTLA-4 and its role in modulating T cell responsiveness.

    David A. Ostrov;Wuxian Shi;Jean-Claude D. Schwartz;Steven C. Almo

  • Structure-Based Discovery of a Novel Angiotensin-Converting Enzyme 2 Inhibitor

    Matthew J. Huentelman;Jasenka Zubcevic;Jose A. Hernández Prada;Xiaodong Xiao

  • A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer.

    Steven N. Hochwald;Carl Nyberg;Min Zheng;Donghang Zheng

  • HLA-A*32:01 is strongly associated with vancomycin-induced drug reaction with eosinophilia and systemic symptoms.

    Katherine C. Konvinse;Jason A. Trubiano;Jason A. Trubiano;Rebecca Pavlos;Ian James

  • Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells

    Ashley T. Martino;Etiena Basner-Tschakarjan;David M. Markusic;Jonathan D. Finn

  • SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation

    Katie D. White;Riichiro Abe;Michael Ardern-Jones;Thomas Beachkofsky

  • Minocycline hepatotoxicity: Clinical characterization and identification of HLA- B*35:02 as a risk factor

    Thomas Jacob Urban;Thomas Jacob Urban;Paola Nicoletti;Naga Chalasani;Jose Serrano

  • Prediction of off-target effects on angiotensin-converting enzyme 2.

    Lidia V. Kulemina;David A. Ostrov

  • T Cell–Mediated Hypersensitivity Reactions to Drugs

    Rebecca Pavlos;Simon Mallal;David Ostrov;Soren Buus

  • Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis

    W Vallen Graham;W Vallen Graham;Weiqi He;Weiqi He;Amanda M Marchiando;Juanmin Zha;Juanmin Zha

  • Islet autoantigens: Structure, function, localization, and regulation

    Peter Arvan;Massimo Pietropaolo;David Ostrov;Christopher J. Rhodes

  • Fever, rash, and systemic symptoms: understanding the role of virus and HLA in severe cutaneous drug allergy.

    Rebecca Pavlos;Simon Mallal;David Ostrov;Yuri Pompeu

  • Resolution of the novel immune-type receptor gene cluster in zebrafish

    Jeffrey A. Yoder;Ronda T. Litman;M. Gail Mueller;Salil Desai

Frequent Co-Authors

Elizabeth J. Phillips
Elizabeth J. Phillips Vanderbilt University Medical Center
Simon Mallal
Simon Mallal Vanderbilt University Medical Center
Gary W. Litman
Gary W. Litman University of South Florida
Silvana Gaudieri
Silvana Gaudieri University of Western Australia
Bjoern Peters
Bjoern Peters La Jolla Institute For Allergy & Immunology
Søren Buus
Søren Buus University of Copenhagen
Marco Salemi
Marco Salemi University of Florida
Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Mina John
Mina John Royal Perth Hospital
Chen Liu
Chen Liu Yale University

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