Christian Bjørbæk

Best Publications

• Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

  Karim El-Haschimi;Dominique D. Pierroz;Stanley M. Hileman;Christian Bjørbæk

  1278
  Citations

• Divergent Signaling Capacities of the Long and Short Isoforms of the Leptin Receptor

  Christian Bjørbæk;Shigeo Uotani;Barbara da Silva;Jeffrey S. Flier

  1260
  Citations

• Identification of SOCS-3 as a Potential Mediator of Central Leptin Resistance

  Christian Bjørbæk;Joel K Elmquist;J.Daniel Frantz;Steven E Shoelson

  1256
  Citations

• Leptin Differentially Regulates NPY and POMC Neurons Projecting to the Lateral Hypothalamic Area

  Carol F Elias;Carl Aschkenasi;Charlotte Lee;Joseph Kelly

  1111
  Citations

• Region-Specific Leptin Resistance within the Hypothalamus of Diet-Induced Obese Mice

  Heike Münzberg;Jeffrey S Flier;Christian Bjørbaek

  1021
  Citations

• The Role of SOCS-3 in Leptin Signaling and Leptin Resistance

  C Bjørbaek;K El-Haschimi;J D Frantz;J S Flier

  914
  Citations

• Leptin Signaling in the Central Nervous System and the Periphery

  Christian Bjørbaek;Barbara B Kahn

  786
  Citations

• Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3

  Jane K Howard;Belinda J Cave;Laura J Oksanen;Laura J Oksanen;Iphigenia Tzameli

  697
  Citations

• SOCS3 Mediates Feedback Inhibition of the Leptin Receptor via Tyr985

  Christian Bjørbæk;Hugh J. Lavery;Sarah H. Bates;Ryan K. Olson

  694
  Citations

• Expression of leptin receptor isoforms in rat brain microvessels.

  Christian Bjørbæk;Joel K. Elmquist;Patrick Michl;Rexford S. Ahima

  476
  Citations

• Regulation of neuronal and glial proteins by leptin: implications for brain development

  Rexford S. Ahima;Christian Bjorbaek;Suzette Osei;Jeffrey S. Flier

  473
  Citations

• Transcriptional regulation of the thyrotropin-releasing hormone gene by leptin and melanocortin signaling.

  Mark Harris;Carl Aschkenasi;Carol Fuzeti Elias;Annie Chandrankunnel

  467
  Citations

• Divergent roles of SHP-2 in ERK activation by leptin receptors.

  Christian Bjørbæk;Ryan M. Buchholz;Sarah M. Davis;Sarah H. Bates

  455
  Citations

• Characterizaton of short isoforms of the leptin receptor in rat cerebral microvessels and of brain uptake of leptin in mouse models of obesity.

  Stanley M. Hileman;Dominique D. Pierroz;Hiroaki Masuzaki;Christian Bjørbæk

  364
  Citations

• Functional properties of leptin receptor isoforms: internalization and degradation of leptin and ligand-induced receptor downregulation.

  Shigeo Uotani;Christian Bjørbæk;Jens Tornøe;Jeffrey S. Flier

  344
  Citations

• Role of Signal Transducer and Activator of Transcription 3 in Regulation of Hypothalamic Proopiomelanocortin Gene Expression by Leptin

  Unknown

  322
  Citations

• Leptin regulates prothyrotropin-releasing hormone biosynthesis. Evidence for direct and indirect pathways.

  Eduardo A. Nillni;Charles Vaslet;Mark Harris;Anthony N. Hollenberg

  302
  Citations

• Leptin revisited: its mechanism of action and potential for treating diabetes

  Unknown

  286
  Citations

• Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function

  Marie Björnholm;Heike Münzberg;Rebecca L. Leshan;Eneida C. Villanueva

  227
  Citations

• Leptin-Dependent Control of Glucose Balance and Locomotor Activity by POMC Neurons

  Unknown

  223
  Citations