His primary areas of study are Mucin, Cell biology, Molecular biology, Immunology and Microbiology. The various areas that Carol Basbaum examines in his Mucin study include Epidermal growth factor, Pathogen and In situ hybridization. His Cell biology research is multidisciplinary, incorporating elements of Epithelium, Respiratory epithelium and Biochemistry.
His work deals with themes such as Complementary DNA, Gene expression, Northern blot, Pathology and Interleukin, which intersect with Molecular biology. His studies in Immunology integrate themes in fields like Pseudomonas aeruginosa, Cell and Cystic fibrosis. His work in Microbiology addresses issues such as Pathogenesis, which are connected to fields such as Lipopolysaccharide, Downregulation and upregulation and Bacteria.
Carol Basbaum mainly focuses on Molecular biology, Mucin, Internal medicine, Endocrinology and Cell biology. His study in Molecular biology is interdisciplinary in nature, drawing from both Complementary DNA, Messenger RNA, Gene expression, Gene and Lysozyme. The concepts of his Mucin study are interwoven with issues in Immunology, Pathogenesis, Respiratory tract, Microbiology and Signal transduction.
In his research on the topic of Immunology, Pseudomonas aeruginosa is strongly related with Cystic fibrosis. His Cell biology course of study focuses on Flagellin and Autocrine signalling. He has researched Submucosal glands in several fields, including Receptor and Degranulation.
Carol Basbaum mainly investigates Molecular biology, Cancer research, Mucin, Immunology and Cell biology. His Molecular biology study incorporates themes from Gene expression, Gene, Transfection, Pranlukast and Pseudomonas aeruginosa. His research integrates issues of CXCR4, Amphiregulin, Epidermal growth factor receptor, Lung cancer and Chemokine receptor in his study of Cancer research.
His Mucin research integrates issues from Epidermal growth factor, Secretion, Microbiology, Signal transduction and Asthma. His Immunology research is multidisciplinary, relying on both Carcinogenesis, Cancer, Wnt signaling pathway and Toxicity. His Cell biology research includes themes of Cellular polarity, Epithelial polarity, Toll-like receptor and Flagellin.
His primary areas of investigation include Mucin, Immunology, Microbiology, Signal transduction and Molecular biology. His research in Mucin intersects with topics in Inflammation, Epidermal growth factor and Endocrinology, Adenosine. His Immunology research is multidisciplinary, incorporating perspectives in Internal medicine, Downregulation and upregulation and Protein kinase A.
The study incorporates disciplines such as NFKB1, Transcription and Pathogenesis in addition to Microbiology. His Signal transduction study combines topics from a wide range of disciplines, such as Receptor, Autocrine signalling, Myeloid Differentiation Factor 88 and TLR5. His studies deal with areas such as c-Raf, Cyclin-dependent kinase 4, Mitogen-activated protein kinase kinase, MAP2K7 and KT5720 as well as Molecular biology.
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Focalized proteolysis: spatial and temporal regulation of extracellular matrix degradation at the cell surface.
Carol B Basbaum;Zena Werb.
Current Opinion in Cell Biology (1996)
Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells
Hassan Lemjabbar;Carol Basbaum.
Nature Medicine (2002)
Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells.
C P Sommerhoff;J A Nadel;C B Basbaum;G H Caughey.
Journal of Clinical Investigation (1990)
Activation of NF-κB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells
Jian-Dong Li;Weijun Feng;Marianne Gallup;Jae-Ho Kim.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Allergen-induced IL-9 directly stimulates mucin transcription in respiratory epithelial cells
M. Longphre;D. Li;M. Gallup;E. Drori.
Journal of Clinical Investigation (1999)
A novel role for murine IL-4 in vivo: induction of MUC5AC gene expression and mucin hypersecretion.
Ui-Angela Temann;Bhagi Prasad;Marianne W. Gallup;Carol Basbaum.
American Journal of Respiratory Cell and Molecular Biology (1997)
Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer
Sae-Kyung Chang;Austin F. Dohrman;Carol B. Basbaum;Samuel B. Ho.
Treatment of Cancer
Ernest Kun Kun;Jerome Mendeleyev;Carol Basbaum;Hassan Lemjabbar-Alaoui.
Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease
Jian-Dong Li;Austin F. Dohrman;Marianne Gallup;Susumu Miyata.
Proceedings of the National Academy of Sciences of the United States of America (1997)
The microvesicle as a vehicle for EMMPRIN in tumor-stromal interactions.
Sukhvinder S Sidhu;Aklilu T Mengistab;Andrew N Tauscher;Jennifer LaVail.
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