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Astrid M. Westendorf

Astrid M. Westendorf

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
14312
World Ranking
15429
National Ranking
1087

Overview

Astrid M. Westendorf is affiliated with the University of Duisburg-Essen in Germany. Their research primarily spans the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Their work covers several focused subfields, including Immunology, Molecular Biology, Oncology, Epidemiology, and Surgery.

A significant portion of Westendorf's research addresses topics related to immune cell function and interaction. Other prominent topics include gut microbiota and health, immunotherapy and immune responses, immune cells in cancer, T-cell and B-cell immunology, cancer immunotherapy and biomarkers, as well as IL-33, ST2, and ILC pathways.

Notable recent publications by Westendorf include:

  • A Pro-Inflammatory Gut Microbiome Characterizes SARS-CoV-2 Infected Patients and a Reduction in the Connectivity of an Anti-Inflammatory Bacterial Network Associates With Severe COVID-19 (2021) in Frontiers in Cellular and Infection Microbiology
  • B cell expansion hinders the stroma-epithelium regenerative cross talk during mucosal healing (2022) in Immunity
  • Modulating gut microbiota in a mouse model of Graves' orbitopathy and its impact on induced disease (2021) in Microbiome
  • Inhibition of TLR4 Signaling Impedes Tumor Growth in Colitis-Associated Colon Cancer (2021) in Frontiers in Immunology
  • Permissive HLA-DPB1 mismatches in HCT depend on immunopeptidome divergence and editing by HLA-DM (2020) in Blood

Westendorf frequently publishes in journals such as Frontiers in Immunology, bioRxiv (Cold Spring Harbor Laboratory), PLoS Pathogens, Frontiers in Cellular and Infection Microbiology, and Blood. The highest number of their publications has appeared in Frontiers in Immunology and bioRxiv, with six papers each.

They have collaborated extensively with several coauthors, including Jan Buer, Wiebke Hansen, Robert Klopfleisch, Torben Knuschke, and Eva Pastille, reflecting a collaborative approach to research within their fields.

Best Publications

  • Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset

    Marc Veldhoen;Catherine Uyttenhove;Jacques van Snick;Helena Helmby

  • The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins.

    Marc Veldhoen;Keiji Hirota;Astrid M. Westendorf;Jan Buer

  • Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota

    Bärbel Stecher;Riccardo Robbiani;Alan W. Walker;Astrid M. Westendorf

  • Frontline: Neuropilin-1: a surface marker of regulatory T cells

    Dunja Bruder;Michael Probst-Kepper;Astrid M. Westendorf;Robert Geffers

  • Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity.

    Sya N. Ukena;Anurag Singh;Ulrike Dringenberg;Regina Engelhardt

  • Gut inflammation can boost horizontal gene transfer between pathogenic and commensal Enterobacteriaceae.

    Bärbel Stecher;Rémy Denzler;Lisa Maier;Florian Bernet

  • Purinergic Control of T Cell Activation by ATP Released Through Pannexin-1 Hemichannels

    Ursula Schenk;Astrid M. Westendorf;Enrico Radaelli;Anna Casati

  • Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway.

    Lydia A. Haile;Reinhard von Wasielewski;Jaba Gamrekelashvili;Christine Krüger

  • ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors

    Ursula Schenk;Michela Frascoli;Michele Proietti;Robert Geffers

  • A network of trans-cortical capillaries as mainstay for blood circulation in long bones

    Anika Grüneboom;Ibrahim Hawwari;Daniela Weidner;Stephan Culemann

  • Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth

    Wiebke Hansen;Marina Hutzler;Simone Abel;Christina Alter

  • Acquired IFNγ resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions.

    Antje Sucker;Fang Zhao;Natalia Pieper;Christina Heeke

  • Hypoxia Enhances Immunosuppression by Inhibiting CD4+ Effector T Cell Function and Promoting Treg Activity.

    Astrid M Westendorf;Kathrin Skibbe;Alexandra Adamczyk;Jan Buer

  • The use of calcium phosphate nanoparticles encapsulating Toll-like receptor ligands and the antigen hemagglutinin to induce dendritic cell maturation and T cell activation.

    Viktoriya Sokolova;Torben Knuschke;Anna Kovtun;Jan Buer

  • On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes.

    Dunja Bruder;Astrid M. Westendorf;Wiebke Hansen;Silvia Prettin

  • Signatures of human regulatory T cells: an encounter with old friends and new players

    Susanne Pfoertner;Andreas Jeron;Michael Probst-Kepper;Carlos A Guzman

  • Cell targeting by antibody-functionalized calcium phosphatenanoparticles

    Diana Kozlova;Svitlana Chernousova;Torben Knuschke;Jan Buer

  • Colonic gene silencing using siRNA-loaded calcium phosphate/PLGA nanoparticles ameliorates intestinal inflammation in vivo.

    Annika Frede;Annika Frede;Bernhard Neuhaus;Robert Klopfleisch;Catherine Walker

  • Mechanism of the uptake of cationic and anionic calcium phosphate nanoparticles by cells

    Viktoriya Sokolova;Diana Kozlova;Torben Knuschke;Jan Buer

  • Frontline: Neuropilin‐1: a surface marker of regulatory T cells (Vol. 34(3) 2004, pp 623–630, DOI 10.1002/eji.200324799)

    Dunja Bruder;Michael Probst-Kepper;Astrid M. Westendorf;Robert Geffers

Frequent Co-Authors

Jan Buer
Jan Buer University of Duisburg-Essen
Matthias Epple
Matthias Epple University of Duisburg-Essen
Robert Geffers
Robert Geffers Helmholtz Centre for Infection Research
Ulf Dittmer
Ulf Dittmer University of Duisburg-Essen
Karl S. Lang
Karl S. Lang University of Duisburg-Essen
Achim D. Gruber
Achim D. Gruber Freie Universität Berlin
Tim Sparwasser
Tim Sparwasser Johannes Gutenberg University of Mainz
Kai Matuschewski
Kai Matuschewski Humboldt-Universität zu Berlin
Verena Jendrossek
Verena Jendrossek University of Duisburg-Essen

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