Alex Zacharek

Best Publications

• Therapeutic benefit of bone marrow stromal cells administered 1 month after stroke.

  Li Hong Shen;Yi Li;Jieli Chen;Alex Zacharek

  493
  Citations

• Endothelial Nitric Oxide Synthase Regulates Brain-Derived Neurotrophic Factor Expression and Neurogenesis after Stroke in Mice

  Jieli Chen;Alex Zacharek;Chunling Zhang;Hao Jiang

  404
  Citations

• Neurorestorative Therapy for Stroke

  Jieli Chen;Poornima Venkat;Alex Zacharek;Michael Chopp;Michael Chopp

  211
  Citations

• MiR-126 Affects Brain-Heart Interaction after Cerebral Ischemic Stroke

  Jieli Chen;Chengcheng Cui;Xiaoping Yang;Jiang Xu

  187
  Citations

• MiR-126 Mediates Brain Endothelial Cell Exosome Treatment-Induced Neurorestorative Effects After Stroke in Type 2 Diabetes Mellitus Mice.

  Poornima Venkat;Chengcheng Cui;Michael Chopp;Michael Chopp;Alex Zacharek

  162
  Citations

• Bone marrow stromal cells upregulate expression of bone morphogenetic proteins 2 and 4, gap junction protein connexin-43 and synaptophysin after stroke in rats.

  C. Zhang;Y. Li;J. Chen;Q. Gao

  150
  Citations

• White matter damage and glymphatic dysfunction in a model of vascular dementia in rats with no prior vascular pathologies.

  Poornima Venkat;Michael Chopp;Michael Chopp;Alex Zacharek;Chengcheng Cui

  147
  Citations

• Niaspan increases angiogenesis and improves functional recovery after stroke

  Jieli Chen;Xu Cui;Alex Zacharek;Hao Jiang

  147
  Citations

• White Matter Damage and the Effect of Matrix Metalloproteinases in Type 2 Diabetic Mice After Stroke

  Jieli Chen;Xu Cui;Alex Zacharek;Yisheng Cui

  143
  Citations

• Nitric Oxide Donor Upregulation of Stromal Cell-Derived Factor-1/Chemokine (CXC Motif) Receptor 4 Enhances Bone Marrow Stromal Cell Migration into Ischemic Brain After Stroke

  Xu Cui;Jieli Chen;Alex Zacharek;Yi Li

  119
  Citations

• Chemokine, vascular and therapeutic effects of combination Simvastatin and BMSC treatment of stroke.

  Xu Cui;Michael Chopp;Michael Chopp;Alex Zacharek;Cynthia Roberts

  113
  Citations

• Role of endothelial nitric oxide synthetase in arteriogenesis after stroke in mice.

  X. Cui;M. Chopp;M. Chopp;A. Zacharek;C. Zhang

  111
  Citations

• Comparison of Bone Marrow Stromal Cells Derived From Stroke and Normal Rats for Stroke Treatment

  Alex Zacharek;Amjad Shehadah;Jieli Chen;Xu Cui

  98
  Citations

• Angiopoietin/Tie2 pathway mediates type 2 diabetes induced vascular damage after cerebral stroke.

  Xu Cui;Michael Chopp;Michael Chopp;Alex Zacharek;Xinchun Ye

  95
  Citations

• Niacin Treatment of Stroke Increases Synaptic Plasticity and Axon Growth in Rats

  Xu Cui;Michael Chopp;Alex Zacharek;Cynthia Roberts

  92
  Citations

• Neuroprotective effect of human placenta-derived cell treatment of stroke in rats.

  Jieli Chen;Amjad Shehadah;Ajai Pal;Alex Zacharek

  92
  Citations

• Simvastatin Increases Notch Signaling Activity and Promotes Arteriogenesis After Stroke

  Alex Zacharek;Jieli Chen;Xu Cui;Yuping Yang

  89
  Citations

• Increasing Ang1/Tie2 expression by simvastatin treatment induces vascular stabilization and neuroblast migration after stroke.

  Jieli Chen;Xu Cui;Alex Zacharek;Michael Chopp;Michael Chopp

  88
  Citations

• Neurorestorative Therapy of Stroke in Type 2 Diabetes Mellitus Rats Treated With Human Umbilical Cord Blood Cells

  Tao Yan;Poornima Venkat;Michael Chopp;Alex Zacharek

  82
  Citations

• MiR‐126 Contributes to Human Umbilical Cord Blood Cell‐Induced Neurorestorative Effects After Stroke in Type‐2 Diabetic Mice

  Jieli Chen;Ruizhuo Ning;Alex Zacharek;Chengcheng Cui

  82
  Citations