Clinical Pharmacology and Therapeutics

Top Research Topics at Clinical Pharmacology & Therapeutics?

Clinical Pharmacology & Therapeutics is organized to address concerns in the fields of Pharmacology, Internal medicine, Pharmacokinetics, Endocrinology and Anesthesia. The journal explores issues in Pharmacology which can be linked to other research areas like Metabolite and Crossover study. Gastroenterology, Oncology and Cardiology are some topics wherein Internal medicine research discussed in Clinical Pharmacology & Therapeutics have an impact.

While work presented in it provided substantial information on Pharmacokinetics, it also covered topics in Oral administration and Bioavailability. Excretion and Urine are all aspects of Endocrinology discussed in Clinical Pharmacology & Therapeutics. The Anesthesia study featured in it draws connections with the study of Placebo.

The main emphasis of Clinical Pharmacology & Therapeutics is the research on Blood pressure, emphasizing the topic of Heart rate. The studies tackled, which mainly focus on Clinical pharmacology, apply to Intensive care medicine as well.

• Pharmacology (37.43%)
• Internal medicine (28.56%)
• Pharmacokinetics (21.47%)

What are the most cited papers published in the journal?

• A method for estimating the probability of adverse drug reactions (7591 citations)
• Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework* (4458 citations)
• Nanoparticles in Medicine: Therapeutic Applications and Developments (1839 citations)

Research areas of the most cited articles at Clinical Pharmacology & Therapeutics:

The published papers focus largely on the fields of Pharmacology, Pharmacokinetics, Internal medicine, Endocrinology and Anesthesia. Metabolite, Pharmacogenetics and Crossover study are some topics wherein Pharmacology research discussed in the most cited papers has an impact. The published papers deal with Internal medicine in conjunction with Genotype and similar fields in Allele.

What topics the last edition of the journal is best known for?

• Internal medicine
• Pharmacology
• Disease

The previous edition focused in particular on these issues:

Clinical Pharmacology & Therapeutics investigates studies in Internal medicine, Pharmacokinetics, Drug, Pharmacology and MEDLINE. While Internal medicine is the focus of the journal, it also provided insights into the studies of Gastroenterology and Oncology. Some problems in Pharmacokinetics that were presented in it overlapped with concepts under Placebo, Adverse effect and Dosing.

The work on Drug presented in it focuses on Drug development in particular. It dives deep in exploring the relationship between the study of Pharmacology and In vivo. Clinical Pharmacology & Therapeutics addresses concerns in MEDLINE which are intertwined with other disciplines, such as Medical physics and Intensive care medicine.

The most cited articles from the last journal are:

• PharmVar GeneFocus: CYP2D6. (36 citations)
• Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C19 and Proton Pump Inhibitor Dosing. (34 citations)
• From Real-World Patient Data to Individualized Treatment Effects Using Machine Learning: Current and Future Methods to Address Underlying Challenges. (29 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

Top authors and change over time

The top authors publishing in Clinical Pharmacology & Therapeutics (based on the number of publications) are:

• David J. Greenblatt (112 papers) absent at the last edition,
• Neal L. Benowitz (99 papers) published 1 paper at the last edition,
• Pertti J. Neuvonen (92 papers) absent at the last edition,
• Alastair J. J. Wood (90 papers) absent at the last edition,
• Teri E. Klein (80 papers) published 9 papers at the last edition, 3 more than at the previous edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Top affiliations and change over time

Only papers with recognized affiliations are considered

The top affiliations publishing in Clinical Pharmacology & Therapeutics (based on the number of publications) are:

• University of California, San Francisco (382 papers) published 13 papers at the last edition, 5 less than at the previous edition,
• Vanderbilt University (300 papers) published 7 papers at the last edition, 6 more than at the previous edition,
• Center for Drug Evaluation and Research (292 papers) published 31 papers at the last edition, 4 more than at the previous edition,
• University of Toronto (270 papers) published 5 papers at the last edition, 2 more than at the previous edition,
• Pfizer (269 papers) published 29 papers at the last edition, 3 less than at the previous edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 6.97% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 33.59% were posted by at least one author from the top 10 institutions publishing in the journal. Another 12.92% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 16.80% of all publications and 36.69% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

• Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
• Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
• Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
• Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
• Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.

Practical Applications and Career Prospects

The theoretical knowledge and practical skills related to Clinical Pharmacology and Therapeutics can be applied in many career paths in the healthcare industry. Particularly, the practical applications can provide a strong foundation for becoming a nurse practitioner. For example, the understanding of pharmacokinetics can help in developing effective and personalized treatment plans for patients. Similarly, proficiency in internal medicine can aid in diagnosing and treating a variety of health conditions in adults. As Clinical Pharmacology & Therapeutics integrates various research areas such as endocrinology, gastroenterology, oncology, and cardiology, it opens up a myriad of opportunities for healthcare professionals to specialize in. Nurse practitioners with a solid understanding of clinical pharmacology can offer a broad range of healthcare services, including patient education, health prevention, diagnosis, and managing chronic diseases. For those interested in furthering their career in this field, you may wish to consider becoming a nurse practitioner in Michigan. This career path requires rigorous training and education, but offers a rewarding opportunity to make a significant impact in patient lives. To learn more about this career path and the steps you need to take, visit how to become a nurse practitioner in Michigan, which provides a comprehensive guide on the subject. This vital knowledge and skillset make clinical pharmacology and therapeutics an integral part of training centered towards patient-focused care delivery. Thus, understanding the research topics in these fields can significantly enhance the practical skills of healthcare professionals and their understanding of patient care.