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Biology and Biochemistry

D-Index
61
Citations
14040
World Ranking
11302
National Ranking
354

Overview

Zhihai Qin is affiliated with the Chinese Academy of Sciences in China and has an extensive publication record in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their research spans key subfields including Molecular Biology, Immunology, Oncology, Cancer Research, and Pulmonary and Respiratory Medicine.

Their recent published papers cover a range of topics relevant to cancer biology, immune response, and cellular processes. Selected papers include:

  • Metabolic reprogramming of cancer-associated fibroblasts and its effect on cancer cell reprogramming (2021, Theranostics)
  • S100A4 enhances protumor macrophage polarization by control of PPAR-γ-dependent induction of fatty acid oxidation (2021, Journal for ImmunoTherapy of Cancer)
  • Tight junctions in the blood-brain barrier promote edema formation and infarct size in stroke - Ambivalent effects of sealing proteins (2020, Journal of Cerebral Blood Flow & Metabolism)
  • Tumor-derived exosomes drive pre-metastatic niche formation in lung via modulating CCL1+ fibroblast and CCR8+ Treg cell interactions (2022, Cancer Immunology Immunotherapy)
  • Inhibiting collagen I production and tumor cell colonization in the lung via miR-29a-3p loading of exosome-/liposome-based nanovesicles (2021, Acta Pharmaceutica Sinica B)

Zhihai Qin has frequently published in the following venues:

  • Cell Biochemistry and Function
  • PubMed
  • arXiv (Cornell University)
  • Journal of Cellular and Molecular Medicine
  • International Journal of Biological Sciences

The scientist collaborates with multiple coauthors regularly, with the most frequent including:

  • Xiaohan Yao
  • Jiajia Wan
  • Xixi Duan
  • Ming Wang
  • Xiaohan Lou

Their main research topics involve:

  • Immune cells in cancer
  • Immunotherapy and Immune Responses
  • Cancer, Hypoxia, and Metabolism
  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • RNA Interference and Gene Delivery
  • Cancer Immunotherapy and Biomarkers

Best Publications

  • CD4+ T Cell–Mediated Tumor Rejection Involves Inhibition of Angiogenesis that Is Dependent on IFNγ Receptor Expression by Nonhematopoietic Cells

    Zhihai Qin;Thomas Blankenstein

  • B cells inhibit induction of T cell-dependent tumor immunity.

    Zhihai Qin;Günther Richter;Thomas Schüler;Sabrina Ibe

  • Activation of STAT6 by STING Is Critical for Antiviral Innate Immunity

    Huihui Chen;Hui Sun;Fuping You;Wenxiang Sun

  • TNF signaling drives myeloid-derived suppressor cell accumulation

    Xueqiang Zhao;Lijie Rong;Xiaopu Zhao;Xiao Li

  • A Critical Requirement of Interferon γ-mediated Angiostasis for Tumor Rejection by CD8+ T Cells

    Zhihai Qin;Johannes Schwartzkopff;Felicia Pradera;Thomas Kammertoens

  • Lipid droplet-dependent fatty acid metabolism controls the immune suppressive phenotype of tumor-associated macrophages.

    Hao Wu;Hao Wu;Hao Wu;Yijie Han;Yasmina Rodriguez Sillke;Yasmina Rodriguez Sillke;Hongzhang Deng

  • Involvement of ERK, p38 and NF‐κB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells

    Huazhang An;Yizhi Yu;Minghui Zhang;Hongmei Xu

  • Mechanisms of rejection induced by tumor cell-targeted gene transfer of interleukin 2, interleukin 4, interleukin 7, tumor necrosis factor, or interferon gamma

    Hanno Hock;Marion Dorsch;Ulrich Kunzendorf;Zhihai Qin

  • Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells.

    Z Qin;G Noffz;M Mohaupt;T Blankenstein

  • Peripheral Nerve Injury Leads to Working Memory Deficits and Dysfunction of the Hippocampus by Upregulation of TNF-α in Rodents

    Wen-Jie Ren;Yong Liu;Li-Jun Zhou;Wei Li

  • T Helper Cell Type 1–associated and Cytotoxic T Lymphocyte–mediated Tumor Immunity Is Impaired in Interleukin 4–deficient Mice

    Thomas Schüler;Zhihai Qin;Sabrina Ibe;Nancy Noben-Trauth

  • TNF-α contributes to up-regulation of Nav1.3 and Nav1.8 in DRG neurons following motor fiber injury.

    Xin-Hua He;Ying Zang;Xi Chen;Rui-Ping Pang

  • Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF

    Xusheng Wang;Haiyan Chen;Ruiyun Tian;Yiling Zhang

  • Tumor Rejection by Disturbing Tumor Stroma Cell Interactions

    Sabrina Ibe;Zhihai Qin;Thomas Schüler;Susanne Preiss

  • Loss of conformational stability in calmodulin upon methionine oxidation.

    Jun Gao;Daniel H. Yin;Yihong Yao;Hongye Sun

  • Designing Liposomes To Suppress Extracellular Matrix Expression To Enhance Drug Penetration and Pancreatic Tumor Therapy.

    Tianjiao Ji;Jiayan Lang;Jing Wang;Rong Cai

  • Transmembrane TNF-α Promotes Suppressive Activities of Myeloid-Derived Suppressor Cells via TNFR2

    Xin Hu;Baihua Li;Xiaoyan Li;Xianxian Zhao

  • Transformable Peptide Nanocarriers for Expeditious Drug Release and Effective Cancer Therapy via Cancer‐Associated Fibroblast Activation

    Tianjiao Ji;Ying Zhao;Yanping Ding;Jing Wang

  • Paradoxical Roles of IL-4 in Tumor Immunity

    Zhiguang Li;Lin Chen;Zhihai Qin

  • Peptide Assembly Integration of Fibroblast‐Targeting and Cell‐Penetration Features for Enhanced Antitumor Drug Delivery

    Tianjiao Ji;Yanping Ding;Ying Zhao;Jing Wang

Frequent Co-Authors

Thomas Blankenstein
Thomas Blankenstein Max Delbrück Center for Molecular Medicine
Xuetao Cao
Xuetao Cao Chinese Academy of Medical Sciences & Peking Union Medical College
Tibor Diamantstein
Tibor Diamantstein Freie Universität Berlin
Guangjun Nie
Guangjun Nie Ministry of Science and Technology
Sergei A. Nedospasov
Sergei A. Nedospasov Lomonosov Moscow State University
Xiyun Yan
Xiyun Yan Chinese Academy of Sciences
Anjie Dong
Anjie Dong Tianjin University
Xian-Guo Liu
Xian-Guo Liu Sun Yat-sen University
Liandong Deng
Liandong Deng Tianjin University

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