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Chemistry

D-Index
45
Citations
7048
World Ranking
16494
National Ranking
4099

Overview

William B. Weglicki is affiliated with George Washington University in the United States. Their research spans various fields and subfields within medicine, focusing particularly on the interactions of trace elements and their impacts on health and disease.

The main areas of study include Medicine and Nursing, with subfields covering Nutrition and Dietetics, Oncology, Physiology, Pathology and Forensic Medicine, and Nephrology. This multidisciplinary approach underscores their work on both clinical and biological aspects of health.

Weglicki's research topics involve several key biomedical and clinical issues:

  • Trace Elements in Health
  • Nitric Oxide and Endothelin Effects
  • Cardiac Ischemia and Reperfusion
  • Magnesium in Health and Disease
  • Vitamin K Research Studies
  • Parathyroid Disorders and Treatments
  • Colorectal Cancer Treatments and Studies

The scientist has contributed to at least three recent papers published between 2020 and 2024. These papers include:

  • Deficiency in gp91Phox (NOX2) Protects against Oxidative Stress and Cardiac Dysfunction in Iron Overloaded Mice, 2020, published in Hearts
  • Experimental Hypomagnesemia Induces Neurogenic Inflammation and Cardiac Dysfunction, 2020, published in Hearts
  • Topical Application of Aprepitant Inhibits Erlotinib-induced Facial Dermatitis/Hair Loss, 2024, published in Journal of Dermatology and Skin Science

Weglicki frequently collaborates with other researchers, including Jay H. Kramer, Joanna J. Chmielinska, I. Tong Mak, Christopher F. Spurney, and Micaela Iantorno. Collaboration frequency indicates ongoing research partnerships, which enhance the scope and depth of investigations.

Publication venues where Weglicki often publishes include:

  • Hearts
  • Journal of Dermatology and Skin Science

The focus of Weglicki's work frequently relates to cardiovascular function and disorders, with particular attention to the roles of oxidative stress, magnesium deficiency, and inflammatory processes in cardiac health. Additionally, the intersection with dermatological applications in the recent study highlights a broader biomedical interest.

Best Publications

  • Identification of free radicals in myocardial ischemia/reperfusion by spin trapping with nitrone DMPO

    Carmen M. Arroyo;Jay H. Kramer;Benjamin F. Dickens;William B. Weglicki

  • Magnesium deficiency in vitro enhances free radical-induced intracellular oxidation and cytotoxicity in endothelial cells

    B.F. Dickens;W.B. Weglicki;Y.-S. Li;I.T. Mak

  • Magnesium-deficiency elevates circulating levels of inflammatory cytokines and endothelin.

    William B. Weglicki;Terry M. Phillips;Anthony M. Freedman;Marie M. Cassidy

  • Spin-trapping evidence that graded myocardial ischemia alters post-ischemic superoxide production

    Jay H. Kramer;Carmen M. Arroyo;Benjamin F. Dickens;William B. Weglicki

  • Antioxidant effects of calcium channel blockers against free radical injury in endothelial cells. Correlation of protection with preservation of glutathione levels.

    Unknown

  • Spin trapping of oxygen and carbon-centered free radicals in ischemic canine myocardium

    C.M. Arroyo;J.H. Kramer;R.H. Leiboff;G.W. Mergner

  • Protective effects of sulfhydryl-containing angiotensin converting enzyme inhibitors against free radical injury in endothelial cells.

    I.Tong Mak;Anthony M. Freedman;Ben F. Dickens;William B. Weglicki

  • Role of free radicals and substance P in magnesium deficiency

    W.B Weglicki;I.T. Mak;J.H. Kramer;B.F. Dickens

  • Protection by beta-blocking agents against free radical-mediated sarcolemmal lipid peroxidation.

    Unknown

  • Temporal relationship of free radical-induced lipid peroxidation and loss of latent enzyme activity in highly enriched hepatic lysosomes.

    I T Mak;H P Misra;W B Weglicki

  • Detection of alkoxyl and carbon-centered free radicals in coronary sinus blood from patients undergoing elective cardioplegia.

    Anthony J. Tortolani;Saul R. Powell;Vladimír Mišik;William B. Weglicki

  • Mechanisms of cardiovascular drugs as antioxidants.

    W.B. Weglicki;I.T. Mak;M.G. Simic

  • Magnesium-deficiency potentiates free radical production associated with postischemic injury to rat hearts: Vitamin E affords protection

    Jay H. Kramer;Vladimír Mišík;William B. Weglicki

  • Erythrocytes from magnesium-deficient hamsters display an enhanced susceptibility to oxidative stress.

    A. M. Freedman;I. T. Mak;R. E. Stafford;B. F. Dickens

  • Enhanced lysosomal phospholipid degradation and lysophospholipid production due to free radicals

    Unknown

  • Magnesium deficiency-induced cardiomyopathy: protection by vitamin E.

    Anthony M. Freedman;Aisar H. Atrakchi;Marie M. Cassidy;William B. Weglicki

  • Biochemical mechanisms for the inotropic effect of the cardiotonic drug milrinone.

    Craig Q. Earl;Joel Linden;William B. Weglicki

  • Enhanced NO production during Mg deficiency and its role in mediating red blood cell glutathione loss

    I. T. Mak;A. M. Komarov;T. L. Wagner;R. E. Stafford

  • Postischemic free radical production in the venous blood of the regionally ischemic swine heart. Effect of deferoxamine.

    G W Mergner;W B Weglicki;J H Kramer

  • Lipid Peroxidation‐Derived Free Radical Production and Postischemic Myocardial Reperfusion Injurya

    Jay H. Kramer;Vladimír. Mišík;William B. Weglicki

  • Dietary magnesium intake influences circulating pro-inflammatory neuropeptide levels and loss of myocardial tolerance to postischemic stress.

    Jay H. Kramer;I. Tong Mak;Terry M. Phillips;William B. Weglicki

  • Protective effects of dihydropyridine Ca-blockers against endothelial cell oxidative injury due to combined nitric oxide and superoxide.

    I. Tong Mak;Jingyun Zhang;William B. Weglicki

  • Neurogenic peptides and the cardiomyopathy of magnesium-deficiency: Effects of substance P-receptor inhibition

    W B Weglicki;I T Mak;R E Stafford;B F Dickens

Frequent Co-Authors

George V. Vahouny
George V. Vahouny George Washington University
Katherine L. Tucker
Katherine L. Tucker University of Massachusetts Lowell
Joel Linden
Joel Linden University of Virginia
Robert J. Siegel
Robert J. Siegel Cedars-Sinai Medical Center
Edward R. Laws
Edward R. Laws Brigham and Women's Hospital
Victor R. Gordeuk
Victor R. Gordeuk University of Illinois at Chicago
Roger S. Blumenthal
Roger S. Blumenthal Johns Hopkins University

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