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Chemistry

D-Index
52
Citations
8337
World Ranking
13656
National Ranking
1006

Overview

Uwe Linne is affiliated with Philipp University of Marburg in Germany. Their research spans multiple fields within biochemistry, genetics, molecular biology, and medicine, with a significant focus on molecular biology and infectious diseases.

The scientist has contributed extensively to the understanding of interferon and immune responses, microbial metabolic engineering and bioproduction, viral gastroenteritis research and epidemiology, NF-κB signaling pathways, SARS-CoV-2 and COVID-19 research, RNA research and splicing, and animal virus infection studies.

Among the recent publications attributed to Uwe Linne are:

  • Coronavirus replication-transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit, 2021, Proceedings of the National Academy of Sciences
  • Multi-level inhibition of coronavirus replication by chemical ER stress, 2021, Nature Communications
  • Correction to: Using a marine microalga as a chassis for polyethylene terephthalate (PET) degradation, 2020, Microbial Cell Factories
  • Dietary cellulose induces anti-inflammatory immunity and transcriptional programs via maturation of the intestinal microbiota, 2020, Gut Microbes
  • Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway, 2020, Proceedings of the National Academy of Sciences

Uwe Linne frequently collaborates with several researchers including Michael Kracht, Axel Weber, M. Lienhard Schmitz, Christin Mayr-Buro, and Johanna Meier-Soelch. These collaborations are reflected in multiple joint publications.

The scientist's work appears predominantly in journals such as Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), mBio, Proceedings of the National Academy of Sciences, and Cancers.

Uwe Linne has published 46 papers overall in biochemistry, genetics, and molecular biology, and 22 papers in the field of medicine. Subfield expertise includes molecular biology with 30 publications, infectious diseases with 11 publications, cancer research and immunology each with 6 publications, and cell biology with 4 publications.

Best Publications

  • Temperature: The “Ignored” Factor at the NanoBio Interface

    Morteza Mahmoudi;Abuelmagd M. Abdelmonem;Shahed Behzadi;Joachim H. Clement

  • Using a marine microalga as a chassis for polyethylene terephthalate (PET) degradation.

    Daniel Moog;Johanna Schmitt;Jana Senger;Jan Zarzycki

  • Isolation and structural characterization of capistruin, a lasso peptide predicted from the genome sequence of Burkholderia thailandensis E264.

    Thomas A Knappe;Uwe Linne;Séverine Zirah;Sylvie Rebuffat

  • Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases

    Dirk Schwarzer;Henning D. Mootz;Uwe Linne;Mohamed A. Marahiel

  • Microalgae as bioreactors for bioplastic production.

    Franziska Hempel;Andrew S Bozarth;Nicole Lindenkamp;Andreas Klingl

  • The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A

    Leif Flühe;Thomas A Knappe;Michael J Gattner;Michael J Gattner;Antje Schäfer

  • Ferri-bacillibactin uptake and hydrolysis in Bacillus subtilis

    Marcus Miethke;Oliver Klotz;Uwe Linne;Jürgen J. May

  • A biosynthetic gene cluster for a secreted cellobiose lipid with antifungal activity from Ustilago maydis.

    Beate Teichmann;Uwe Linne;Sandra Hewald;Mohamed A. Marahiel

  • Identification of a Gene Cluster for Biosynthesis of Mannosylerythritol Lipids in the Basidiomycetous Fungus Ustilago maydis

    Sandra Hewald;Uwe Linne;Mario Scherer;Mohamed A. Marahiel

  • Functional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxin

    Holger Webert;Sven-Andreas Freibert;Angelo Gallo;Torsten Heidenreich

  • Control of directionality in nonribosomal peptide synthesis: role of the condensation domain in preventing misinitiation and timing of epimerization.

    Uwe Linne;Mohamed A. Marahiel

  • Insights into the Biosynthesis and Stability of the Lasso Peptide Capistruin

    Thomas A. Knappe;Uwe Linne;Lars Robbel;Mohamed A. Marahiel

  • Physical‐chemical plant‐derived signals induce differentiation in Ustilago maydis

    Artemio Mendoza-Mendoza;Patrick Berndt;Armin Djamei;Carolin Weise

  • Synthesis and Derivatization of Daptomycin: A Chemoenzymatic Route to Acidic Lipopeptide Antibiotics

    Jan Grünewald;Stephan A Sieber;Christoph Mahlert;Uwe Linne

  • Mutational analysis of the C‐domain in nonribosomal peptide synthesis

    Veit Bergendahl;Uwe Linne;Mohamed A. Marahiel

  • Insights into the Unique Phosphorylation of the Lasso Peptide Paeninodin

    Shaozhou Zhu;Julian D. Hegemann;Christopher D. Fage;Marcel Zimmermann

  • Introducing Lasso Peptides as Molecular Scaffolds for Drug Design: Engineering of an Integrin Antagonist

    Thomas A. Knappe;Florian Manzenrieder;Carlos Mas-Moruno;Uwe Linne

  • The Linear Pentadecapeptide Gramicidin Is Assembled by Four Multimodular Nonribosomal Peptide Synthetases That Comprise 16 Modules with 56 Catalytic Domains

    Nadine Kessler;Holger Schuhmann;Sabrina Morneweg;Uwe Linne

  • Covalent inhibition of SUMO and ubiquitin-specific cysteine proteases by an in situ thiol–alkyne addition

    Stefanie Sommer;Nadine D. Weikart;Uwe Linne;Henning D. Mootz

  • Portability of epimerization domain and role of peptidyl carrier protein on epimerization activity in nonribosomal peptide synthetases.

    Uwe Linne;Sascha Doekel;Mohamed A. Marahiel

Frequent Co-Authors

Mohamed A. Marahiel
Mohamed A. Marahiel Philipp University of Marburg
Xiulan Xie
Xiulan Xie Philipp University of Marburg
Dirk Schwarzer
Dirk Schwarzer Max Planck Society
Lars-Oliver Essen
Lars-Oliver Essen Philipp University of Marburg
Michael Bölker
Michael Bölker Philipp University of Marburg
Sylvie Rebuffat
Sylvie Rebuffat Centre national de la recherche scientifique, CNRS
Uwe G. Maier
Uwe G. Maier Philipp University of Marburg
Gerhard Klebe
Gerhard Klebe Philipp University of Marburg
Stephan A. Sieber
Stephan A. Sieber Technical University of Munich
Morteza Mahmoudi
Morteza Mahmoudi Michigan State University

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