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Tamotsu Takahashi

Tamotsu Takahashi

D-Index & Metrics

Chemistry

D-Index
66
Citations
14905
World Ranking
7313
National Ranking
480

Overview

Tamotsu Takahashi is a researcher affiliated with Hokkaido University in Japan. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with an emphasis on subfields such as Molecular Medicine, Pharmacology, Endocrinology, and Applied Microbiology and Biotechnology.

The main topics of Takahashi's research include:

  • Antibiotic Resistance in Bacteria
  • Antibiotics Pharmacokinetics and Efficacy
  • Enterobacteriaceae and Cronobacter Research
  • Antibiotic Use and Resistance

Takahashi has contributed to recent scientific literature with publications focusing on bacterial resistance and treatment responses. Notable papers include:

  • "The Clinical Evaluation of Third-generation Cephalosporins As Definitive Therapy for Enterobacter spp. and Klebsiella aerogenes Bacteremia," published in 2022 in Internal Medicine
  • "Evaluation of predictors of third-generation cephalosporin non-susceptibility and factors affecting recurrence or death in bacteremia caused by Citrobacter freundii complex, Enterobacter cloacae complex, and Klebsiella aerogenes," published in 2024 in the Journal of Chemotherapy

The frequent publication venues for Takahashi's works include:

  • Internal Medicine
  • Journal of Chemotherapy

Collaboration with peers is a significant aspect of Takahashi's research activities. Frequent coauthors include:

  • Kazuhiro Kobayashi
  • Atsuko Hata
  • Waki Imoto
  • Shigeki Kakuno
  • Wataru Shibata

Best Publications

  • Reaction of zirconocene dichloride with alkyllithiums or alkyl grignard reagents as a convenient method for generating a “zirconocene” equivalant and its use in zirconium-promoted cyclization of alkenes, alkynes, dienes, enynes, and diynes☆

    Ei-ichi Negishi;Fredrik E Cederbaum;Tamotsu Takahashi

  • Metal-promoted cyclization. 19. Novel bicyclization of enynes and diynes promoted by zirconocene derivatives and conversion of zirconabicycles into bicyclic enones via carbonylation

    Eiichi Negishi;Steven J. Holmes;James M. Tour;Joseph A. Miller

  • Patterns of Stoichiometric and Catalytic Reactions of Organozirconium and Related Complexes of Synthetic Interest

    Ei-Ichi Negishi;Tamotsu Takahashi

  • Palladium- or nickel-catalyzed reactions of alkenylmetals with unsaturated organic halides as a selective route to arylated alkenes and conjugated dienes: scope, limitations, and mechanism

    E. Negishi;T. Takahashi;S. Baba;D.E. Van Horn

  • Cycloaddition Reaction of Zirconacyclopentadienes to Alkynes: Highly Selective Formation of Benzene Derivatives from Three Different Alkynes

    Tamotsu Takahashi;Zhenfeng Xi;Akiko Yamazaki;Yuanhong Liu

  • Selective preparation of pyridines, pyridones, and iminopyridines from two different alkynes via azazirconacycles.

    Tamotsu Takahashi;Fu-Yu Tsai;Yanzhong Li;Hui Wang

  • Facile cleavage of the CβCβ′ bond of zirconacyclopentenes. Convenient method for selectively coupling alkynes with alkynes, nitriles, and aldehydes

    Tamotsu Takahashi;Motohiro Kageyama;Victor Denisov;Ryuichiro Hara

  • Remarkably pair- and regioselective carbon-carbon bond-forming reaction of zirconacyclopentane derivatives with Grignard reagents

    Tamotsu Takahashi;Takashi Seki;Yu Nitto;Masahiko Saburi

  • Alkene and Alkyne Complexes of Zirconocene. Their Preparation, Structure, and Novel Transformations.

    Ei-ichi Negishi;Tamotsu Takahashi

  • Copper-Mediated Coupling of Zirconacyclopentadienes with Dihalo Aromatic Compounds. Formation of Fused Aromatic Rings

    Tamotsu Takahashi;Ryuichiro Hara;Yasushi Nishihara;Martin Kotora

  • Straightforward Method for Synthesis of Highly Alkyl-Substituted Naphthacene and Pentacene Derivatives by Homologation

    Tamotsu Takahashi;Masanori Kitamura;and Baojian Shen;Kiyohiko Nakajima

  • Multiple Mechanistic Pathways for Zirconium-Catalyzed Carboalumination of Alkynes. Requirements for Cyclic Carbometalation Processes Involving C−H Activation

    Ei-ichi Negishi;Denis Y. Kondakov;Danièle Choueiry;Kayoko Kasai

  • Organozirconium Compounds in Organic Synthesis

    Ei-ichi Negishi;Tamotsu Takahashi

  • Carbon−Carbon Bond Formation Reaction of Zirconacyclopentadienes with Alkynes in the Presence of Ni(II)-complexes

    Tamotsu Takahashi;Fu-Yu Tsai;Yanzhong Li;Kiyohiko Nakajima

  • Zirconium-catalyzed, highly regioselective hydrosilation reaction of alkenes and X-ray structures of silyl(hydrido)zirconocene derivatives

    Tamotsu Takahashi;Maki Hasegawa;Noriyuki Suzuki;Masahiko Saburi

  • Coupling reaction of zirconacyclopentadienes with dihalonaphthalenes and dihalopyridines: a new procedure for the preparation of substituted anthracenes, quinolines, and isoquinolines.

    Tamotsu Takahashi;Yanzhong Li;Petr Stepnicka;Masanori Kitamura

  • Carbon-Carbon Bond Cleavage and Selective Transformation of Zirconacycles

    Tamotsu Takahashi;Martin Kotora;Ryuichiro Hara;Zhenfeng Xi

  • Highly Selective and Practical Alkyne-Alkyne Cross-Coupling Using Cp2ZrBu2 and Ethylene

    Zhenfeng Xi;Ryuichiro Hara;Tamotsu Takahashi

  • Selective Formation of Substituted Pyridines from Two Different Alkynes and a Nitrile: Novel Coupling Reaction of Azazirconacyclopentadienes with Alkynes

    Tamotsu Takahashi;and Fu-Yu Tsai;Martin Kotora

  • Metal-promoted cyclization. 28. Regioselective and diastereoselective alkyl-alkene and alkene-alkene coupling promoted by zirconocene and hafnocene

    Douglas R. Swanson;Christophe J. Rousset;Eiichi Negishi;Tamotsu Takahashi

Frequent Co-Authors

Masamichi Ogasawara
Masamichi Ogasawara University of Tokushima
Martin Kotora
Martin Kotora Charles University
Kiyohiko Nakajima
Kiyohiko Nakajima Aichi University of Education
Ei-ichi Negishi
Ei-ichi Negishi Purdue University West Lafayette
Noriyuki Suzuki
Noriyuki Suzuki National Institute for Environmental Studies
Chanjuan Xi
Chanjuan Xi Tsinghua University
Wen-Hua Sun
Wen-Hua Sun Chinese Academy of Sciences
Yasushi Nishihara
Yasushi Nishihara Okayama University
Masanobu Hidai
Masanobu Hidai University of Tokyo
Zhenfeng Xi
Zhenfeng Xi Peking University

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