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Biology and Biochemistry

D-Index
64
Citations
22885
World Ranking
9466
National Ranking
4178

Overview

Stephan Ladisch is affiliated with the Children's National Health System in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with contributions to several specialized subfields including Immunology, Hematology, Infectious Diseases, Clinical Psychology, and Physiology.

The scientist's work focuses on multiple main topics, reflecting a broad engagement with immune-related disorders and interactions. These include:

  • Autoimmune and Inflammatory Disorders Research
  • Immune Cell Function and Interaction
  • Parvovirus B19 Infection Studies
  • Family and Disability Support Research
  • Histiocytic Disorders and Treatments
  • Mast cells and histamine
  • Viral-associated cancers and disorders

Among their recent scholarly publications are several papers addressing critical issues in hematology and immunology:

  • "T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsis" (2020, Blood)
  • "Stem cell transplantation for children with hemophagocytic lymphohistiocytosis: results from the HLH-2004 study" (2020, Blood Advances)
  • "IFN-γ signature in the plasma proteome distinguishes pediatric hemophagocytic lymphohistiocytosis from sepsis and SIRS" (2021, Blood Advances)
  • "Langerhans cell histiocytosis: NACHO update on progress, chaos, and opportunity on the path to rational cures" (2024, Cancer)
  • "Assessment of intrathecal therapy in the treatment of familial haemophagocytic lymphohistiocytosis" (2025, British Journal of Haematology)

Ladisch's frequent co-authors, each with multiple joint publications, include M M Henry, Michelle L. Hermiston, Michael Jeng, Carl E. Allen, and Kenneth L. McClain. This group collaboration suggests a close network in the fields of hematology and immunology research.

Their publications are commonly found in well-regarded peer-reviewed journals such as Blood Advances, Blood, Cancer, and the British Journal of Haematology, reflecting a focus on clinical and translational immunology and hematologic diseases.

This scientist's research addresses key topics in immune cell function and pathology related to blood disorders, infections, and immune dysregulation, with particular attention to pediatric conditions such as hemophagocytic lymphohistiocytosis and Langerhans cell histiocytosis.

Best Publications

  • HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis.

    Jan-Inge Henter;Annacarin Horne;Maurizio Aricó;R Maarten Egeler

  • Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation.

    Jan-Inge Henter;AnnaCarin Samuelsson-Horne;Maurizio Aricò;R Maarten Egeler

  • Contemporary classification of histiocytic disorders

    Blaise E. Favara;Alfred C. Feller;Macro Pauli;Elaine S. Jaffe

  • Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol.

    Helena Trottestam;AnnaCarin Horne;Maurizio Aricò;R. Maarten Egeler

  • Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study

    Elisabet Bergsten;Elisabet Bergsten;AnnaCarin Horne;AnnaCarin Horne;Maurizio Aricó;Itziar Astigarraga

  • HISTTOCYTOSIS SYNDROMES IN CHILDREN

    Tony Chu;G.J. D'Angio;S. Ladisch;M. Nesbit

  • HLH‐94: A treatment protocol for hemophagocytic lymphohistiocytosis

    J I Henter;M Aricò;R M Egeler;G Elinder

  • A randomized trial of treatment for multisystem Langerhans' cell histiocytosis.

    Helmut Gadner;Nicole Grois;Maurizio Arico;Valerie Broadbent

  • Therapy prolongation improves outcome in multisystem Langerhans cell histiocytosis

    Helmut Gadner;Milen Minkov;Nicole Grois;Ulrike Pötschger

  • Construction of long DNA molecules using long PCR‐based fusion of several fragments simultaneously

    Nikolai A. Shevchuk;Anton V. Bryksin;Yevgeniya A. Nusinovich;Felipe C. Cabello

  • Improved outcome in multisystem Langerhans cell histiocytosis is associated with therapy intensification.

    Helmut Gadner;Nicole Grois;Ulrike Pötschger;Milen Minkov

  • Treatment strategy for disseminated langerhans cell histiocytosis

    Helmut Gadner;Andreas Heitger;Nicole Grois;Irmgard Gatterer-Menz

  • Risk factors for diabetes insipidus in langerhans cell histiocytosis.

    N. Grois;U. Pötschger;H. Prosch;M. Minkov

  • Challenges in the diagnosis of hemophagocytic lymphohistiocytosis: Recommendations from the North American Consortium for Histiocytosis (NACHO).

    Michael B. Jordan;Carl E. Allen;Jay Greenberg;Michael Henry

  • Haematopoietic stem cell transplantation in haemophagocytic lymphohistiocytosis.

    AnnaCarin Horne;Gritta Janka;R. Maarten Egeler;Helmut Gadner

  • Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosis.

    AnnaCarin Horne;Helena Trottestam;Maurizio Aricò;R. Maarten Egeler

  • Shedding and immunoregulatory activity of YAC-1 lymphoma cell gangliosides.

    Stephan Ladisch;Baiba K. Gillard;Clifford Wong;Lisa Ulsh

  • Expression of GD2 ganglioside by untreated primary human neuroblastomas.

    Zi-Liang Wu;Eileen Schwartz;Robert Seeger;Stephan Ladisch

  • How I treat Langerhans cell histiocytosis

    Carl E. Allen;Stephan Ladisch;Kenneth L. McClain

  • Tumor gangliosides inhibit the tumor-specific immune response.

    Robert McKallip;Ruixiang Li;Stephan Ladisch

Frequent Co-Authors

Helmut Gadner
Helmut Gadner St Anna Children's Hospital
Jan-Inge Henter
Jan-Inge Henter Karolinska University Hospital
Maurizio Aricò
Maurizio Aricò Azienda USL di Pescara
Alexandra H. Filipovich
Alexandra H. Filipovich Cincinnati Children's Hospital Medical Center
Jean Donadieu
Jean Donadieu University of Paris-Saclay
David G. Poplack
David G. Poplack Baylor College of Medicine
Scott Montgomery
Scott Montgomery Örebro University
Douglas A. Gage
Douglas A. Gage Michigan State University
R. Michael Blaese
R. Michael Blaese National Institutes of Health
Philip A. Pizzo
Philip A. Pizzo Stanford University

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