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12730
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Overview

Philip S. Insel is affiliated with the University of California, San Francisco in the United States. Their research predominantly focuses on medicine, with significant contributions in psychiatry and mental health, physiology, and cognitive neuroscience. They have also engaged in work related to statistics and probability as well as experimental and cognitive psychology.

The main topics of Insel's work encompass dementia and cognitive impairment research, Alzheimer's disease research and treatments, and functional brain connectivity studies. Additional areas of study include advanced neuroimaging techniques and applications, anxiety, depression, psychometrics, treatment, cognitive processes, obsessive-compulsive spectrum disorders, and statistical methods in clinical trials.

Insel has published frequently in several scientific journals. The primary venues for their work include:

  • Alzheimer s & Dementia
  • American Journal of Geriatric Psychiatry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the International Neuropsychological Society
  • Brain

The following recent papers exemplify Philip S. Insel's research contributions:

  • "Neuroanatomical spread of amyloid β and tau in Alzheimer's disease: implications for primary prevention" (2020) published in Brain Communications
  • "Association of Sleep and β-Amyloid Pathology Among Older Cognitively Unimpaired Adults" (2021) published in JAMA Network Open
  • "Aβ deposition is associated with increases in soluble and phosphorylated tau that precede a positive Tau PET in Alzheimer's disease" (2020) published in Science Advances
  • "Early stages of tau pathology and its associations with functional connectivity, atrophy and memory" (2021) published in Brain
  • "Mild behavioral impairment and its relation to tau pathology in preclinical Alzheimer's disease" (2021) published in Translational Psychiatry

Philip S. Insel has collaborated frequently with several researchers, including:

  • R. Scott Mackin
  • Niklas Mattsson
  • Oskar Hansson
  • Michelle T. Kassel
  • Michael Donohue

Best Publications

  • Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials.

    Lon S. Schneider;Karen S. Dagerman;Philip Insel

  • Efficacy and adverse effects of atypical antipsychotics for dementia: meta-analysis of randomized, placebo-controlled trials.

    Lon S. Schneider;Karen Dagerman;Philip S. Insel

  • Development and assessment of a composite score for memory in the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

    Paul K. Crane;Adam Carle;Laura E. Gibbons;Philip Insel

  • A composite score for executive functioning, validated in Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment

    Laura E. Gibbons;Adam C. Carle;R. Scott Mackin;Danielle J Harvey

  • Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease

    Jacob W. Vogel;Yasser Iturria-Medina;Olof T. Strandberg;Ruben Smith

  • Plasma tau in Alzheimer disease

    Niklas Mattsson;Henrik Zetterberg;Henrik Zetterberg;Henrik Zetterberg;Shorena Janelidze;Philip S. Insel

  • Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease

    Sebastian Palmqvist;Philip S Insel;Philip S Insel;Erik Stomrud;Shorena Janelidze

  • Aβ deposition is associated with increases in soluble and phosphorylated tau that precede a positive Tau PET in Alzheimer's disease.

    Niklas Mattsson-Carlgren;Emelie Andersson;Shorena Janelidze;Rik Ossenkoppele;Rik Ossenkoppele

  • Associations between tau, Aβ, and cortical thickness with cognition in Alzheimer disease.

    Rik Ossenkoppele;Ruben Smith;Tomas Ohlsson;Olof Strandberg

  • Cerebrospinal fluid tau, neurogranin, and neurofilament light in Alzheimer's disease.

    Niklas Mattsson;Philip S Insel;Philip S Insel;Sebastian Palmqvist;Erik Portelius

  • Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease.

    Niklas Mattsson;Niklas Mattsson;Niklas Mattsson;Philip S. Insel;Philip S. Insel;Michael Donohue;Susan Landau

  • Serum Neurofilament Light Chain for Prognosis of Outcome After Cardiac Arrest.

    Marion Moseby-Knappe;Niklas Mattsson;Niklas Nielsen;Henrik Zetterberg

  • Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2

    Clifford R. Jack;Josephine Barnes;Matt A. Bernstein;Bret J. Borowski

  • Association of brain amyloid-β with cerebral perfusion and structure in Alzheimer’s disease and mild cognitive impairment

    Niklas Mattsson;Niklas Mattsson;Niklas Mattsson;Duygu Tosun;Duygu Tosun;Philip S. Insel;Philip S. Insel;Alix Simonson;Alix Simonson

  • Early stages of tau pathology and its associations with functional connectivity, atrophy and memory.

    David Berron;Jacob W Vogel;Philip S Insel;Philip S Insel;Joana B Pereira

  • 18F-AV-1451 and CSF T-tau and P-tau as biomarkers in Alzheimer's disease

    Niklas Mattsson;Michael Schöll;Olof Strandberg;Ruben Smith

  • Treatment With Cholinesterase Inhibitors and Memantine of Patients in the Alzheimer’s Disease Neuroimaging Initiative

    Lon S. Schneider;Philip S. Insel;Michael W. Weiner

  • Cognitive reserve associated with FDG-PET in preclinical Alzheimer disease.

    Michael Ewers;Philip S. Insel;Yaakov Stern;Michael W. Weiner

  • The Brain Health Registry: An internet-based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies

    Michael W. Weiner;Rachel Nosheny;Rachel Nosheny;Monica Camacho;Monica Camacho;Diana Truran-Sacrey

  • Mild behavioral impairment and its relation to tau pathology in preclinical Alzheimer's disease.

    Maurits Johansson;Erik Stomrud;Philip S. Insel;Antoine Leuzy

  • Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects

    G. C. Chiang;G. C. Chiang;P. S. Insel;D. Tosun;D. Tosun;N. Schuff;N. Schuff

Frequent Co-Authors

Michael W. Weiner
Michael W. Weiner University of California, San Francisco
R. Scott Mackin
R. Scott Mackin University of California, San Francisco
Duygu Tosun
Duygu Tosun University of California, San Francisco
Henrik Zetterberg
Henrik Zetterberg University of Gothenburg
Kaj Blennow
Kaj Blennow University of Gothenburg
Sebastian Palmqvist
Sebastian Palmqvist Lund University
Clifford R. Jack
Clifford R. Jack Mayo Clinic
Erik Stomrud
Erik Stomrud Lund University
William J. Jagust
William J. Jagust University of California, Berkeley
John Q. Trojanowski
John Q. Trojanowski University of Pennsylvania

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